Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(546 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(227 prodotti)
- HSP(180 prodotti)
- Integrina(269 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(126 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3904 prodotti di "Ciclo cellulare/Checkpoint"
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GPRP acetate (67869-62-9 free base)
CAS:GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.
Formula:C20H35N7O7Purezza:>99.99%Colore e forma:SolidPeso molecolare:485.53BS-181 dihydrochloride
CAS:BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.Formula:C22H34Cl2N6Colore e forma:SolidPeso molecolare:453.46Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Formula:C17H24ClNO4Purezza:99.75%Colore e forma:SolidPeso molecolare:341.83WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Formula:C21H24F3N7O2Purezza:>99.99% - ≥95%Colore e forma:SolidPeso molecolare:463.46TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Formula:C13H12Cl2N4Purezza:96.05% - 99.82%Colore e forma:SolidPeso molecolare:295.171,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Formula:C14H8O2Purezza:95.96% - 97.01%Colore e forma:Orange Brown SolidPeso molecolare:208.21CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Formula:C16H20FNO3Purezza:99.75%Colore e forma:SolidPeso molecolare:293.33Ref: TM-T9632
1mg56,00€5mg119,00€10mg187,00€25mg316,00€50mg472,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)114,00€Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Formula:C6H5N5O3Purezza:99.28%Colore e forma:SolidPeso molecolare:195.14PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Formula:C18H21Cl3N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:415.75DMT-2′Fluoro-dU Phosphoramidite
CAS:DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Formula:C39H46FN4O8PPurezza:99.5%Colore e forma:SolidPeso molecolare:748.78MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Formula:C24H25F3N6SPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:486.56Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Formula:C22H22FN5O7Purezza:99.82% - 99.93%Colore e forma:SolidPeso molecolare:487.44Ref: TM-TQ0063
1mg105,00€5mg245,00€10mg389,00€25mg645,00€50mg888,00€100mg1.234,00€500mg2.457,00€1mL*10mM (DMSO)264,00€TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Formula:C13H13Cl3N4Colore e forma:SolidPeso molecolare:331.63Ibezapolstat
CAS:Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Formula:C18H20Cl2N6O2Purezza:98% - 99.429%Colore e forma:SolidPeso molecolare:423.3Ref: TM-T10243
1mg54,00€5mg114,00€10mg185,00€25mg369,00€50mg594,00€100mg952,00€1mL*10mM (DMSO)127,00€5'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Formula:C9H12FN3O4Purezza:99.67%Colore e forma:White SolidPeso molecolare:245.21IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purezza:97.73%Colore e forma:SolidPeso molecolare:485.45Ref: TM-T9010
1mg40,00€5mg96,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€1mL*10mM (DMSO)131,00€Mitonafide
CAS:Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.
Formula:C16H15N3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:313.31Ref: TM-T25817
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg188,00€50mg311,00€100mg510,00€200mg728,00€500mg1.093,00€CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formula:C18H17F3N6O2Purezza:99.50%Colore e forma:SolidPeso molecolare:406.36Ref: TM-T9521
1mg60,00€5mg122,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)142,00€Apcin-A
CAS:Apcin-A is an anaphase-promoting complex (APC) inhibitor.Formula:C10H14Cl3N5O2Colore e forma:SolidPeso molecolare:342.61Palbociclib dihydrochloride
Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.Formula:C24H31Cl2N7O2Colore e forma:SolidPeso molecolare:520.45
