Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(545 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(249 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(124 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3859 prodotti di "Ciclo cellulare/Checkpoint"
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USP25/28 inhibitor AZ1
CAS:USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.Formula:C17H16BrF4NO2Purezza:99.79% - 99.86%Colore e forma:SolidPeso molecolare:422.21Ref: TM-T7685
1mg34,00€5mg66,00€10mg92,00€25mg200,00€50mg304,00€100mg447,00€500mg982,00€1mL*10mM (DMSO)73,00€Pyrintegrin
CAS:Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Formula:C23H25N5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:451.54Ref: TM-T16695
1mg78,00€2mg90,00€5mg150,00€10mg215,00€25mg385,00€50mg595,00€100mg858,00€1mL*10mM (DMSO)165,00€SBC-115076
CAS:SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.Formula:C31H33N3O5Purezza:97.07% - 99.89%Colore e forma:SolidPeso molecolare:527.61Ref: TM-T2626
1mg38,00€2mg50,00€5mg80,00€10mg94,00€25mg172,00€50mg309,00€100mg477,00€500mg1.063,00€1mL*10mM (DMSO)87,00€Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formula:C28H27N3O3Colore e forma:SolidPeso molecolare:453.53WR99210
CAS:WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.Formula:C14H18Cl3N5O2Purezza:98.8%Colore e forma:SolidPeso molecolare:394.68ID-8
CAS:ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.Formula:C16H14N2O4Purezza:99.32%Colore e forma:SolidPeso molecolare:298.29Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:543.61Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurezza:98.68% - 99.64%Colore e forma:SolidPeso molecolare:401.46TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formula:C11H10Cl2N4Purezza:97.73% - 99%Colore e forma:SolidPeso molecolare:269.13Ref: TM-T2069
1mg37,00€2mg48,00€5mg72,00€10mg96,00€25mg188,00€50mg366,00€100mg545,00€1mL*10mM (DMSO)79,00€AZ191
CAS:AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor.Formula:C24H27N7OPurezza:98.04% - 99.65%Colore e forma:SolidPeso molecolare:429.52Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Formula:C30H57N7O10Purezza:98.84%Colore e forma:SolidPeso molecolare:675.81GNF4877
CAS:GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.Formula:C25H27FN6O4Purezza:98.68% - 99.40%Colore e forma:SolidPeso molecolare:494.52Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€1mL*10mM (DMSO)69,00€SAR407899
CAS:SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Formula:C14H16N2O2Purezza:99.42%Colore e forma:SolidPeso molecolare:244.29Ref: TM-T7391
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg319,00€200mg474,00€1mL*10mM (DMSO)55,00€USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Formula:C18H11Cl2N3O3S3Purezza:98.5% - 98.71%Colore e forma:SolidPeso molecolare:484.4Ref: TM-T4338
1mg40,00€5mg96,00€10mg152,00€25mg268,00€50mg429,00€100mg703,00€200mg954,00€1mL*10mM (DMSO)94,00€BSJ-4-116
CAS:BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.Formula:C40H49ClN8O8SPurezza:99.09%Colore e forma:SolidPeso molecolare:837.38ML364
CAS:ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.Formula:C24H18F3N3O3S2Purezza:99.35% - >99.99%Colore e forma:SolidPeso molecolare:517.54CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Formula:C22H21ClN2O3Purezza:98.15% - ≥95%Colore e forma:SolidPeso molecolare:396.87Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formula:C9H12N2O5SPurezza:99.91%Colore e forma:SolidPeso molecolare:260.27GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Formula:C20H22N2O5Purezza:98.71%Colore e forma:SolidPeso molecolare:370.4Ref: TM-T8535
1mg54,00€5mg111,00€10mg177,00€25mg299,00€50mg430,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)128,00€
