Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(545 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(248 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(124 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3857 prodotti di "Ciclo cellulare/Checkpoint"
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AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formula:C24H26F3N7O2Purezza:99.59%Colore e forma:SolidPeso molecolare:501.5CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formula:C27H27N7O2SPurezza:95.44% - 99.4%Colore e forma:SolidPeso molecolare:513.61BVDV-IN-1
CAS:BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Formula:C20H22N4OPurezza:98.43%Colore e forma:SolidPeso molecolare:334.41Ref: TM-T9103
1mg38,00€5mg86,00€10mg124,00€25mg241,00€50mg355,00€100mg507,00€200mg687,00€1mL*10mM (DMSO)95,00€PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purezza:99.14% - 99.75%Colore e forma:SolidPeso molecolare:501.5OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurezza:98.69%Colore e forma:SolidPeso molecolare:533.59Ref: TM-T5485
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€1mL*10mM (DMSO)220,00€HMN-176
CAS:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Formula:C20H18N2O4SPurezza:98.92% - 98.99%Colore e forma:SolidPeso molecolare:382.43Ref: TM-T3643
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg178,00€50mg333,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)74,00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purezza:98.2%Colore e forma:SolidPeso molecolare:501.62Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purezza:98.95%Colore e forma:SolidPeso molecolare:432.9Ref: TM-T7167
1mg34,00€2mg46,00€5mg67,00€10mg90,00€25mg130,00€50mg203,00€100mg305,00€200mg447,00€1mL*10mM (DMSO)75,00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purezza:97.01% - 98.38%Colore e forma:SolidPeso molecolare:552.43Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases
Formula:C24H29N7O2·HClPurezza:99.73% - >99.99%Colore e forma:SolidPeso molecolare:483.99Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurezza:97.53%Colore e forma:SolidPeso molecolare:284.34Ref: TM-T4228
1mg39,00€2mg52,00€5mg86,00€10mg140,00€25mg226,00€50mg408,00€100mg600,00€1mL*10mM (DMSO)90,00€Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFormula:C76H121N19O25SPurezza:98.96%Colore e forma:SolidPeso molecolare:1732.95CVT-313
CAS:CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Formula:C20H28N6O3Purezza:97.46% - 97.97%Colore e forma:SolidPeso molecolare:400.47GW779439X
CAS:GW779439X is an inhibitor of CDK.Formula:C22H21F3N8Purezza:97.87%Colore e forma:SolidPeso molecolare:454.45Ref: TM-T8866
1mg58,00€2mg82,00€5mg113,00€10mg178,00€25mg404,00€50mg592,00€100mg845,00€1mL*10mM (DMSO)124,00€Raltitrexed
CAS:Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.Formula:C21H22N4O6SPurezza:98.99% - 99.29%Colore e forma:Yellow Crystalline PowderPeso molecolare:458.49AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurezza:98.4% - 99.51%Colore e forma:SolidPeso molecolare:503.58Ref: TM-T6380
1mg49,00€5mg92,00€10mg158,00€25mg286,00€50mg442,00€100mg645,00€500mg1.341,00€1mL*10mM (DMSO)100,00€MKC3946
CAS:MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.Formula:C21H20N2O3SPurezza:99.65%Colore e forma:SolidPeso molecolare:380.46Ref: TM-TQ0101
1mg52,00€2mg73,00€5mg97,00€10mg160,00€25mg311,00€50mg472,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)110,00€2′-O-Methylcytidine
CAS:2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.Formula:C10H15N3O5Purezza:99.72%Colore e forma:SolidPeso molecolare:257.24Palbociclib Isethionate
CAS:Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。
Formula:C24H29N7O2·C2H6O4SPurezza:99.01% - 99.27%Colore e forma:SolidPeso molecolare:573.66ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formula:C17H21ClN2O4SPurezza:99.33% - 99.45%Colore e forma:SolidPeso molecolare:384.88
