Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(544 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(47 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(230 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(272 prodotti)
- PKC(120 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3835 prodotti di "Ciclo cellulare/Checkpoint"
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NSC23005
CAS:NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).Formula:C13H17NO4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:283.34Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formula:C29H24Cl2N2O7SPurezza:99.39% - 99.66%Colore e forma:SolidPeso molecolare:615.48TH287 hydrochloride
CAS:TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Formula:C11H11Cl3N4Purezza:>99.99%Colore e forma:SolidPeso molecolare:305.59ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formula:C10H12N6OPurezza:99.69%Colore e forma:SolidPeso molecolare:232.24Trilaciclib
CAS:Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Formula:C24H30N8OPurezza:99.624%Colore e forma:SolidPeso molecolare:446.55Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formula:C26H30FN7O3Purezza:98.43% - 99.29%Colore e forma:SolidPeso molecolare:507.56N6,N6-Dimethyladenosine
CAS:N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
Formula:C12H17N5O4Purezza:98.79%Colore e forma:White PowderPeso molecolare:295.29Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purezza:99.6%Colore e forma:SolidPeso molecolare:253.735-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formula:C15H17BrN2O9Purezza:99%Colore e forma:SolidPeso molecolare:449.212'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Formula:C10H14N2O5SPurezza:99.89%Colore e forma:SolidPeso molecolare:274.29CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formula:C18H15F5N8OPurezza:99.37%Colore e forma:SolidPeso molecolare:454.36Ref: TM-T40290
1mg157,00€5mg378,00€10mg612,00€25mg1.251,00€50mg1.972,00€100mg2.673,00€1mL*10mM (DMSO)416,00€O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Formula:C11H15N5O4Purezza:99.57%Colore e forma:SolidPeso molecolare:281.275-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purezza:99.89%Colore e forma:White PowderPeso molecolare:323.12'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formula:C10H12IN5O3Purezza:99.37%Colore e forma:SolidPeso molecolare:377.14P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Formula:C11H15N3O5Purezza:99.71%Colore e forma:SolidPeso molecolare:269.25Ref: TM-TNU1281
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€2',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.Formula:C21H40N2O6Si2Purezza:99.88%Colore e forma:SolidPeso molecolare:472.722'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Formula:C11H15N5O4Purezza:99.79%Colore e forma:SolidPeso molecolare:281.27Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurezza:98.28%Colore e forma:SolidPeso molecolare:415.46Ref: TM-T37113
1mg38,00€5mg80,00€10mg111,00€25mg183,00€50mg269,00€100mg393,00€200mg560,00€1mL*10mM (DMSO)92,00€Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formula:C15H27N7O8Purezza:98.29%Colore e forma:SolidPeso molecolare:433.42DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purezza:99.13%Colore e forma:SolidPeso molecolare:349.34Ref: TM-T37655
1mg73,00€5mg160,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€1mL*10mM (DMSO)170,00€
