Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(542 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(48 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(180 prodotti)
- Integrina(238 prodotti)
- Chinesina(88 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(275 prodotti)
- PKC(117 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(5 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3828 prodotti di "Ciclo cellulare/Checkpoint"
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Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formula:C20H22N4O5SPurezza:99.39% - 99.39%Colore e forma:SolidPeso molecolare:430.48Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Colore e forma:SolidPeso molecolare:435.86Cdc7-IN-17
CAS:Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Formula:C13H15N5OSColore e forma:SolidPeso molecolare:289.36KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formula:C28H38N4O5S2Purezza:98.45%Colore e forma:SolidPeso molecolare:574.76CDK8/19-IN-51
CAS:CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formula:C23H22N6O2Purezza:98.65% - 99.62%Colore e forma:SoildPeso molecolare:414.46BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purezza:98.87%Colore e forma:SolidPeso molecolare:536.37Ref: TM-T14676
1mg108,00€5mg264,00€10mg371,00€25mg665,00€50mg874,00€100mg1.063,00€200mg1.423,00€1mL*10mM (DMSO)311,00€LSN 3213128
CAS:LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.Formula:C17H16FN3O4S2Colore e forma:SolidPeso molecolare:409.45Myt1-IN-1
CAS:Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].Formula:C16H15ClN4O2Colore e forma:SolidPeso molecolare:330.773'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formula:C9H15N2O14P3Colore e forma:SolidPeso molecolare:468.14CDK8-IN-7
CAS:CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Formula:C30H40N2Colore e forma:SolidPeso molecolare:428.65XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formula:C25H21Cl2N3O8Purezza:99.94%Colore e forma:SolidPeso molecolare:562.36HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Formula:C24H19ClFN5O3Colore e forma:SolidPeso molecolare:479.89MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Formula:C15H12I2O4Colore e forma:SolidPeso molecolare:510.06Cdc7-IN-15
CAS:Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].Formula:C12H14N4OSColore e forma:SolidPeso molecolare:262.33CP681301
CAS:CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.Formula:C17H22N4OColore e forma:SolidPeso molecolare:298.38DNA Gyrase-IN-2
CAS:DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.Formula:C24H24N8OS2Colore e forma:SolidPeso molecolare:504.63CDK7-IN-15
CAS:CDK7-IN-15 (Compound 8) is an effective CDK7 inhibitor for studying cancers associated with transcriptional dysregulation.Formula:C21H24F4N6OSPurezza:99.27%Colore e forma:SolidPeso molecolare:484.51CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Formula:C24H26N2O2Purezza:98.18% - 98.86%Colore e forma:SolidPeso molecolare:374.48APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purezza:99.8%Colore e forma:SolidPeso molecolare:440.5Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Formula:C7H4O3S2Purezza:98.50%Colore e forma:White To Off-White PowderPeso molecolare:200.23
