Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(112 prodotti)
- CDK(541 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(47 prodotti)
- DYRK(48 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(180 prodotti)
- Integrina(240 prodotti)
- Chinesina(88 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(276 prodotti)
- PKC(117 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(5 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3824 prodotti di "Ciclo cellulare/Checkpoint"
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10-Formyl-5,8-dideazafolic acid
CAS:10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.Formula:C22H21N5O7Purezza:96.04%Colore e forma:SolidPeso molecolare:467.43CH-1504
CAS:CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.Formula:C23H23N5O5Colore e forma:SolidPeso molecolare:449.46MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Formula:C23H25ClN4O2Colore e forma:SolidPeso molecolare:424.92BSJ-01-175
CAS:BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.Formula:C30H33ClN6O2Colore e forma:SolidPeso molecolare:545.08DENV-IN-7
CAS:DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.Formula:C24H22O8Colore e forma:SolidPeso molecolare:438.43USP28-IN-3
CAS:USP28-IN-3 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Formula:C23H20Cl2N2O3SPurezza:99.92%Colore e forma:SolidPeso molecolare:475.39CDK7-IN-10
CAS:CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)Formula:C29H35N7O3Colore e forma:SolidPeso molecolare:529.63CDK7-IN-16
CAS:CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Formula:C19H21F3N6O2SColore e forma:SolidPeso molecolare:454.47DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Formula:C21H21F2N5O3SColore e forma:SolidPeso molecolare:461.49Ref: TM-T82569
1mg205,00€5mg528,00€10mg782,00€25mg1.161,00€50mg1.558,00€100mg2.322,00€1mL*10mM (DMSO)537,00€P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Formula:C15H17NO3Colore e forma:SolidPeso molecolare:259.3Antibacterial agent 89
CAS:Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.Formula:C21H10Cl2F3NO5SColore e forma:SolidPeso molecolare:516.27CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formula:C16H18N2O7SPurezza:99.95%Colore e forma:SolidPeso molecolare:382.39WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Formula:C13H15BrCl2N2O4SPurezza:98.09%Colore e forma:SolidPeso molecolare:446.14Ref: TM-T73295
1mg71,00€5mg152,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€1mL*10mM (DMSO)167,00€BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Formula:C17H16FN5O3SPurezza:98%Colore e forma:SolidPeso molecolare:389.4Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purezza:98%Colore e forma:SolidPeso molecolare:641.41KIRA-7
CAS:KIRA-7: imidazopyrazine, anti-fibrotic, inhibits IRE1α RNase (IC50: 110 nM) allosterically.Formula:C27H23FN6OColore e forma:SolidPeso molecolare:466.51DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Formula:C28H32N4O4SiColore e forma:SolidPeso molecolare:516.66ROCK2-IN-5
ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.Formula:C23H25N3O5SColore e forma:SolidPeso molecolare:455.53HBV-IN-22
CAS:HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).Formula:C26H29N3O2S2Colore e forma:SolidPeso molecolare:479.66CDK9-IN-14
CAS:CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Formula:C21H23F2N3O4Colore e forma:SolidPeso molecolare:419.42
