Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(112 prodotti)
- CDK(527 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(259 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(284 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(77 prodotti)
Mostrare 10 più sottocategorie
Trovati 3766 prodotti di "Ciclo cellulare/Checkpoint"
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5-Aminouridine
CAS:5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Formula:C9H13N3O6Purezza:99.53%Colore e forma:SolidPeso molecolare:259.22Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formula:C18H17N7O2SColore e forma:SolidPeso molecolare:395.44Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Formula:C32H33F3N8O5Purezza:98.27%Colore e forma:SolidPeso molecolare:666.65Cdc7-IN-4
CAS:Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Formula:C22H24F3N5O4Purezza:98%Colore e forma:SolidPeso molecolare:479.45Valategrast
CAS:Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.Formula:C30H32Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:604.95CM03
CAS:CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.Formula:C34H44N6O6Purezza:98.65%Colore e forma:SolidPeso molecolare:632.75R-82913
CAS:R-82913 blocks RNA-polymerase, lowers mouse DOI-head-shakes, halts 13 HIV-1 strains with 0.15µM IC50, beats AZT-TP by 20x; ineffective on HIV-2.Formula:C16H20ClN3SColore e forma:SolidPeso molecolare:321.87UCK2 Inhibitor-1
CAS:UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 µM .Formula:C27H21N3O4SColore e forma:SolidPeso molecolare:483.54RTC14
CAS:RTC14 induces PTC readthrough, restoring dystrophin and aiding muscle function in Duchenne model mice.Formula:C17H18N2O3Colore e forma:SolidPeso molecolare:298.34Epiroprim
CAS:Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor with antibacterial activity, inhibiting Staphylococcus and Streptococcus.Formula:C19H23N5O2Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:353.42Cdc7-IN-5
CAS:Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.Formula:C25H23N3O5Purezza:98.4%Colore e forma:SolidPeso molecolare:445.47Ref: TM-T10727
1mg96,00€5mg227,00€10mg376,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)250,00€12(S)-HpETE
CAS:12(S)-HpETE activates human blood leukocyte 5-LOE and mediates induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.Formula:C20H32O4Colore e forma:SolidPeso molecolare:336.47DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Formula:C21H21F2N5O3SColore e forma:SolidPeso molecolare:461.49Ref: TM-T82569
1mg216,00€5mg557,00€10mg825,00€25mg1.225,00€50mg1.644,00€100mg2.452,00€1mL*10mM (DMSO)567,00€MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Formula:C23H25ClN4O2Colore e forma:SolidPeso molecolare:424.92BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C16H17N3Colore e forma:SolidPeso molecolare:251.33CDK8-IN-10
CAS:CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.Formula:C25H15ClF3N5O3Colore e forma:SolidPeso molecolare:525.87CDK12-IN-E9
CAS:CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Formula:C24H30N6O2Colore e forma:SolidPeso molecolare:434.53β-catenin-IN-3
CAS:β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces theFormula:C19H20Br2N2OSColore e forma:SolidPeso molecolare:484.25PD-1/PD-L1-IN-NP19
CAS:PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.Formula:C33H31ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:555.06BMVC2
CAS:BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.Formula:C28H25I2N3Colore e forma:SolidPeso molecolare:657.33
