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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3764 prodotti di "Ciclo cellulare/Checkpoint"

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  • BSJ-01-175
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    BSJ-01-175

    CAS:
    BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.
    Formula:C30H33ClN6O2
    Colore e forma:Solid
    Peso molecolare:545.08

    Ref: TM-T63841

  • Tenofovir exalidex
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    Tenofovir exalidex

    CAS:
    Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant
    Formula:C28H52N5O5P
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:569.72

    Ref: TM-T28946

  • DNA Gyrase-IN-5
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    DNA Gyrase-IN-5

    CAS:
    DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.
    Formula:C25H15BrClN5
    Colore e forma:Solid
    Peso molecolare:500.78

    Ref: TM-T63395

  • Syntelin
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    Syntelin

    CAS:
    Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.
    Formula:C21H20N6O2S3
    Colore e forma:Solid
    Peso molecolare:484.62

    Ref: TM-T71828

  • BPIC
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    BPIC

    CAS:
    BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.
    Formula:C27H20N2O5
    Colore e forma:Solid
    Peso molecolare:452.46

    Ref: TM-T23816

  • Zalunfiban
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    Zalunfiban

    CAS:
    RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.
    Formula:C16H18N8O2S
    Colore e forma:Solid
    Peso molecolare:386.43

    Ref: TM-T24746

  • MDK6204
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    MDK6204

    CAS:
    MDK6204 is a selective inhibitor of CLK1 and CLK2.
    Formula:C20H20N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:360.41

    Ref: TM-T24439

  • CLK1-IN-2
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    CLK1-IN-2

    CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.
    Formula:C16H12Cl2N2O2S
    Colore e forma:Solid
    Peso molecolare:367.25

    Ref: TM-T73321

  • Cylindrospermopsin
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    Cylindrospermopsin

    CAS:
    Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.
    Formula:C15H21N5O7S
    Colore e forma:Solid
    Peso molecolare:415.42

    Ref: TM-T35770

  • TDRL-X80
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    TDRL-X80

    CAS:
    TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).
    Formula:C23H15ClN2O6
    Colore e forma:Solid
    Peso molecolare:450.83

    Ref: TM-T62730

  • Digeranyl bisphosphonate
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    Digeranyl bisphosphonate

    CAS:
    Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl
    Formula:C21H34Na4O6P2
    Purezza:98.5%
    Colore e forma:Solid
    Peso molecolare:536.4

    Ref: TM-T12452

  • PF-2771
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    PF-2771

    CAS:
    PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
    Formula:C29H36ClN5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:554.08

    Ref: TM-T12434

  • Binucleine 2
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    Binucleine 2

    CAS:
    Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.
    Formula:C13H11ClFN5
    Colore e forma:Solid
    Peso molecolare:291.71

    Ref: TM-T36801

  • BPKDi
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    BPKDi

    CAS:
    BPKDi is a potent and selective inhibitor of PKD (protein kinase D).
    Formula:C21H28N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:380.49

    Ref: TM-T25172

  • IRE1α kinase-IN-7
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    IRE1α kinase-IN-7

    CAS:
    IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic
    Formula:C28H25F3N6O
    Colore e forma:Solid
    Peso molecolare:518.53

    Ref: TM-T72641

  • WF-536 Hydrochloride
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    WF-536 Hydrochloride

    CAS:
    WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.
    Formula:C14H16ClN3O
    Colore e forma:Solid
    Peso molecolare:277.75

    Ref: TM-T29156

  • BA-1049
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    BA-1049

    CAS:
    BA-1049 is a selective ROCK2 inhibitor.
    Formula:C16H21N3O2S
    Colore e forma:Solid
    Peso molecolare:319.42

    Ref: TM-T70024

  • Cyclapolin 9
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    Cyclapolin 9

    CAS:
    Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.
    Formula:C9H4F3N3O4S
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:307.21

    Ref: TM-T22700

  • Aloisine A
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    Aloisine A

    CAS:
    Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.
    Formula:C16H17N3O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:267.33

    Ref: TM-T21377

  • XIE18-6
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    XIE18-6

    CAS:
    XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.
    Formula:C18H15NO6S
    Purezza:99.712%
    Colore e forma:Solid
    Peso molecolare:373.38

    Ref: TM-T29166