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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3756 prodotti di "Ciclo cellulare/Checkpoint"

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  • BI-1950
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    BI-1950

    CAS:
    BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.
    Formula:C32H26Cl2FN7O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:646.5

    Ref: TM-T14558

  • (2S,3R)-Voruciclib
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    (2S,3R)-Voruciclib

    CAS:
    (2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
    Formula:C22H19ClF3NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.84

    Ref: TM-T10096

  • Logo CymitQuimica
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    Teclistamab

    CAS:
    Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.
    Purezza:95%
    Colore e forma:Liquid

    Ref: TM-T76881

  • DDD85646
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    DDD85646

    CAS:
    DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
    Formula:C21H24Cl2N6O2S
    Purezza:97.8% - 99.76%
    Colore e forma:Solid
    Peso molecolare:495.43

    Ref: TM-T27135

  • Sovesudil
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    Sovesudil

    CAS:
    Sovesudil (PHP-201) is a potent ROCK inhibitor with IC50 of 3.7 nM/2.3 nM for ROCK-I/II; lowers IOP without hyperemia.
    Formula:C23H22FN3O3
    Colore e forma:Solid
    Peso molecolare:407.44

    Ref: TM-T62036

  • 5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
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    5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt N-Bzm5 C Phosphoramidite is a strong modified nucleic acid analog for antisense oligos.
    Formula:C49H56N5O9P
    Colore e forma:Solid
    Peso molecolare:889.97

    Ref: TM-T74704

  • ROCK-IN-9
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    ROCK-IN-9

    CAS:
    <p>ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.</p>
    Formula:C20H20FN5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:381.4

    Ref: TM-T79833

  • L-739758
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    L-739758

    CAS:
    L-739758 is a glycoprotein IIb/IIIa inhibitor.
    Formula:C22H26N4O5S3
    Colore e forma:Solid
    Peso molecolare:522.66

    Ref: TM-T70281

  • Kif15-IN-2
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    Kif15-IN-2

    CAS:
    Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.
    Formula:C20H20N6O4S
    Purezza:98.17%
    Colore e forma:Solid
    Peso molecolare:440.48

    Ref: TM-T11759

  • VER-00158411
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    VER-00158411

    CAS:
    VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).
    Formula:C31H34N6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:538.64

    Ref: TM-T17223

  • CDK9-IN-29
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    CDK9-IN-29

    CAS:
    <p>CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.</p>
    Formula:C29H33F2N5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:553.6

    Ref: TM-T82757

  • GGTI 2147
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    GGTI 2147

    CAS:
    GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
    Formula:C28H30N4O3
    Purezza:98.24%
    Colore e forma:Solid
    Peso molecolare:470.56

    Ref: TM-T25450

  • WRN inhibitor 4
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    WRN inhibitor 4

    CAS:
    <p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>
    Formula:C16H14N2O5S
    Colore e forma:Solid
    Peso molecolare:346.36

    Ref: TM-T80773

  • WRN inhibitor 3
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    WRN inhibitor 3

    CAS:
    WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).
    Formula:C20H20N2O5S
    Colore e forma:Solid
    Peso molecolare:400.45

    Ref: TM-T80774

  • CDK-IN-11
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    CDK-IN-11

    CAS:
    CDK-IN-11, a heterocyclic compound, promotes cardiomyocyte maturation [1].
    Formula:C25H21BrN4O2
    Colore e forma:Solid
    Peso molecolare:489.36

    Ref: TM-T84917

  • αvβ1 integrin-IN-2
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    αvβ1 integrin-IN-2

    CAS:
    <p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>
    Formula:C29H38N4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:506.64

    Ref: TM-T79792

  • USP1-IN-3
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    USP1-IN-3

    CAS:
    USP1-IN-3 is a selective inhibitor of USPI that inhibits USPI-UAFI (IC50<30 nM). USP1-IN-3 can be used to study cancer.
    Formula:C27H24F3N7O
    Colore e forma:Solid
    Peso molecolare:519.52

    Ref: TM-T63625

  • CCT251455
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    CCT251455

    CAS:
    <p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>
    Formula:C26H26ClN7O2
    Purezza:99.1% - 99.1%
    Colore e forma:Solid
    Peso molecolare:503.98

    Ref: TM-T14906

  • DNA polymerase-IN-3
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    DNA polymerase-IN-3

    CAS:
    DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in
    Formula:C13H12O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:232.23

    Ref: TM-T79308

  • c-Myc inhibitor 8
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    c-Myc inhibitor 8

    CAS:
    c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.
    Formula:C19H12BrClF3NO3S2
    Colore e forma:Solid
    Peso molecolare:538.79

    Ref: TM-T72619