CymitQuimica logo
Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

Mostrare 10 più sottocategorie

Trovati 3756 prodotti di "Ciclo cellulare/Checkpoint"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • PD-1/PD-L1-IN-34
    Targetmol
    + Info

    PD-1/PD-L1-IN-34

    CAS:
    PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) effectively inhibits the PD-1/PD-L1 interaction (IC 50 = 0.029 μM) and demonstrates selective binding affinity to PD-L1
    Formula:C35H33ClN2O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:565.1

    Ref: TM-T79205

  • Aurora Kinases-IN-4
    Targetmol
    + Info

    Aurora Kinases-IN-4

    CAS:
    Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.
    Formula:C26H28N8O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:468.55

    Ref: TM-T78753

  • PD-1/PD-L1-IN-26
    Targetmol
    + Info

    PD-1/PD-L1-IN-26

    CAS:
    PD-1/PD-L1-IN-26 is a strong inhibitor with IC50 of 0.0380 μM that may boost immune response in cancer by aiding CD4+ T cell entry to tumors.
    Formula:C43H52N4O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:752.89

    Ref: TM-T72668

  • PD-1/PD-L1-IN-27
    Targetmol
    + Info

    PD-1/PD-L1-IN-27

    CAS:
    PD-1/PD-L1-IN-27: potent anti-cancer, IC50 134nM, minimal T cell harm, boosts CD8+ T cells, reduces fatigue.
    Formula:C44H35NO6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:673.75

    Ref: TM-T72680

  • BVDU 5′-Triphosphate
    Targetmol
    + Info

    BVDU 5′-Triphosphate

    CAS:
    BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.
    Formula:C11H16BrN2O14P3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:573.08

    Ref: TM-T80655

  • ASC-69
    Targetmol
    + Info

    ASC-69

    CAS:
    ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].
    Formula:C19H19N7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:345.4

    Ref: TM-T82960

  • KSP-IA
    Targetmol
    + Info

    KSP-IA

    CAS:
    KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.
    Formula:C21H22F2N2O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:356.41

    Ref: TM-T24271

  • Cdc7-IN-7
    Targetmol
    + Info

    Cdc7-IN-7

    CAS:
    <p>Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.</p>
    Formula:C21H22N4O5
    Purezza:98.78%
    Colore e forma:Solid
    Peso molecolare:410.42

    Ref: TM-T10729

  • 8-Azahypoxanthine
    Targetmol
    + Info

    8-Azahypoxanthine

    CAS:
    8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
    Formula:C4H3N5O
    Purezza:99.66%
    Colore e forma:Light Yellow To Light Beige Fine Crystalline
    Peso molecolare:137.1

    Ref: TM-T20102

  • m-Se3
    Targetmol
    + Info

    m-Se3

    CAS:
    m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
    Formula:C29H23IN2Se
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:605.37

    Ref: TM-T79872

  • αvβ6 integrin inhibitor 2
    Targetmol
    + Info

    αvβ6 integrin inhibitor 2

    CAS:
    αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.
    Formula:C21H30N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:386.49

    Ref: TM-T79140

  • PVZB1194
    Targetmol
    + Info

    PVZB1194

    CAS:
    PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through
    Formula:C13H9F4NO2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:319.28

    Ref: TM-T78125

  • Trovafloxacin mesylate
    Targetmol
    + Info

    Trovafloxacin mesylate

    CAS:
    Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
    Formula:C21H19F3N4O6S
    Purezza:99.18%
    Colore e forma:Solid
    Peso molecolare:512.46

    Ref: TM-T13231L

  • Synstatin (92-119)
    Targetmol
    + Info

    Synstatin (92-119)

    CAS:
    Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and
    Formula:C133H207N35O46
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3032.27

    Ref: TM-T78064

  • Litronesib
    Targetmol
    + Info

    Litronesib

    CAS:
    Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
    Formula:C23H37N5O4S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:511.7

    Ref: TM-T11859L

  • PD-L1-IN-2
    Targetmol
    + Info

    PD-L1-IN-2

    CAS:
    PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.
    Formula:C33H38N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:586.68

    Ref: TM-T78053

  • WRN inhibitor 1
    Targetmol
    + Info

    WRN inhibitor 1

    CAS:
    WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.
    Formula:C16H13FN2O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:348.35

    Ref: TM-T79107

  • ON 108600
    Targetmol
    + Info

    ON 108600

    CAS:
    ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.
    Formula:C22H14Cl2N2O6S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:537.39

    Ref: TM-T79908

  • ICAM-1-IN-1
    Targetmol
    + Info

    ICAM-1-IN-1

    CAS:
    <p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>
    Formula:C15H11BrN2O2S
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:363.23

    Ref: TM-T13147

  • COH1
    Targetmol
    + Info

    COH1

    CAS:
    COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].
    Formula:C11H10N2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:250.27

    Ref: TM-T78814