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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3756 prodotti di "Ciclo cellulare/Checkpoint"

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  • TC-A 2317 hydrochloride
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    TC-A 2317 hydrochloride

    CAS:
    <p>TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.</p>
    Formula:C19H29ClN6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:392.93

    Ref: TM-T23426

  • Logo CymitQuimica
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    CDK7-IN-25

    CAS:
    CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].
    Formula:C33H32N6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:560.65

    Ref: TM-T79881

  • T521
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    T521

    CAS:
    T521 is a selective inhibitor of the PBD of Plk1 and shows no inhibitory effect on Plk2 and Plk3.
    Formula:C17H14FNO5S2
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:395.43

    Ref: TM-T28904

  • Homouridine
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    Homouridine

    CAS:
    Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).
    Formula:C10H14N2O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:258.23

    Ref: TM-T79190

  • ML-099
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    ML-099

    CAS:
    ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
    Formula:C14H13NO2S
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:259.32

    Ref: TM-T22991

  • Cdc7-IN-12
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    Cdc7-IN-12

    CAS:
    Cdc7-IN-12, a sub-1 nM CDC7 inhibitor, may aid cancer research; hinders COLO205 cell growth (IC50: 100-1000 nM).
    Formula:C16H14N2O2S
    Colore e forma:Solid
    Peso molecolare:298.36

    Ref: TM-T60659

  • Myt1-IN-3
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    Myt1-IN-3

    CAS:
    Myt1-IN-3 is a potent inhibitor of Myt1 (IC50 <10 nM) [1].
    Formula:C18H19N5O2
    Colore e forma:Solid
    Peso molecolare:337.38

    Ref: TM-T61056

  • CDK4/6-IN-15
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    CDK4/6-IN-15

    CAS:
    CDK4/6-IN-15: Oral, selective CDK4/6 inhibitor, halts cancer cell growth, G1 arrest, suppresses Rb phosphorylation.
    Formula:C21H27FN8S
    Colore e forma:Solid
    Peso molecolare:442.56

    Ref: TM-T72928

  • Xylocydine
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    Xylocydine

    CAS:
    Xylocydine is a novel Cdk inhibitor that induces apoptosis in HCC, suppresses tumor growth, and is non-toxic to other tissues.
    Formula:C12H14BrN5O5
    Colore e forma:Solid
    Peso molecolare:388.17

    Ref: TM-T68875

  • SZ-015268
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    SZ-015268

    CAS:
    SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.
    Formula:C25H38N8O3
    Colore e forma:Solid
    Peso molecolare:498.62

    Ref: TM-T63383

  • CI 972 anhydrous
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    CI 972 anhydrous

    CAS:
    CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
    Formula:C11H12ClN5OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:297.76

    Ref: TM-T14964

  • Inixaciclib
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    Inixaciclib

    CAS:
    Inixaciclib is a potent CDK inhibitor, can be used to research anticancer.
    Formula:C26H30F2N6O
    Colore e forma:Solid
    Peso molecolare:480.55

    Ref: TM-T69662

  • Myt1-IN-2
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    Myt1-IN-2

    CAS:
    Myt1-IN-2, a highly potent Myt1 inhibitor, exhibits remarkable anticancer properties with an IC50 value below 10 nM (WO2021195782A1; compound 28) [1].
    Formula:C18H16N6O2S
    Colore e forma:Solid
    Peso molecolare:380.42

    Ref: TM-T61615

  • 2'-Deoxypseudoisocytidine
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    2'-Deoxypseudoisocytidine

    CAS:
    2'-Deoxypseudoisocytidine is a nucleoside analogue.
    Formula:C9H13N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:227.22

    Ref: TM-T10099

  • SHP2/CDK4-IN-1
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    SHP2/CDK4-IN-1

    CAS:
    SHP2/CDK4-IN-1: dual inhibitor, oral, potent (IC50: SHP2 4.3 nM, CDK4 18.2 nM), hinders TNBC growth, strong antitumor effects in mice.
    Formula:C33H35ClF2N10OS
    Colore e forma:Solid
    Peso molecolare:693.21

    Ref: TM-T72836

  • Alatrofloxacin
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    Alatrofloxacin

    CAS:
    Alatrofloxacin is a prodrug of trovafloxacin.
    Formula:C26H25F3N6O5
    Colore e forma:Solid
    Peso molecolare:558.51

    Ref: TM-T23703

  • Raluridine
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    Raluridine

    CAS:
    Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.
    Formula:C9H10ClFN2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:264.64

    Ref: TM-T19689

  • NITD008
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    NITD008

    CAS:
    <p>NITD008 (7-Deaza-2'-C-acetylene-adenosine) is an adenosine nucleoside inhibitor with antiviral activity that inhibits dengue and Zika viruses.</p>
    Formula:C13H14N4O4
    Purezza:98.04%
    Colore e forma:Solid
    Peso molecolare:290.27

    Ref: TM-T16325

  • USP7-IN-12
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    USP7-IN-12

    CAS:
    USP7-IN-12 (compound 1) is a potent, orally active inhibitor of Usp7, exhibiting an IC50 of 3.67 nM and demonstrating antiproliferative activity [1].
    Formula:C29H28ClFN4O2S
    Colore e forma:Solid
    Peso molecolare:551.07

    Ref: TM-T79164

  • G4/HDAC-IN-1
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    G4/HDAC-IN-1

    G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.
    Formula:C36H49ClFN7O4
    Colore e forma:Solid
    Peso molecolare:698.27

    Ref: TM-T72946