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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"

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  • Diguanosine 5′-triphosphate
    Targetmol
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    Diguanosine 5′-triphosphate

    CAS:
    Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.
    Formula:C20H27N10O18P3
    Colore e forma:Solid
    Peso molecolare:788.409

    Ref: TM-T40776

  • CDK7/9-IN-1
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    CDK7/9-IN-1

    CAS:
    CDK7/9-IN-1 inhibits CDK7/9 with IC50: 0.0656 μM (no pre-incubation), 0.00574 μM (3h pre-inc.), and CDK9: 2.14 μM (3h pre-inc.) for cancer research.
    Formula:C24H32F3N5O2
    Colore e forma:Solid
    Peso molecolare:479.548

    Ref: TM-T40353

  • Logo CymitQuimica
    Targetmol
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    Anti-c-myc Antibody (9E10)

    Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-960

  • 5'-O-DMT-rI
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    5'-O-DMT-rI

    CAS:
    5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].
    Formula:C31H30N4O7
    Colore e forma:Solid
    Peso molecolare:570.59

    Ref: TM-T37140

  • Psammaplin A
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    Psammaplin A

    CAS:
    <p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>
    Formula:C22H24Br2N4O6S2
    Colore e forma:Solid
    Peso molecolare:664.38

    Ref: TM-T36303

  • 16,16-dimethyl Prostaglandin A1
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    16,16-dimethyl Prostaglandin A1

    CAS:
    16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.
    Formula:C22H36O4
    Colore e forma:Solid
    Peso molecolare:364.526

    Ref: TM-T36040

  • Logo CymitQuimica
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    DSPE-PEG3000-iRGD

    DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.
    Colore e forma:Odour Solid

    Ref: TM-TCL-01149

  • 5'-O-DMT-N4-Ac-2'-F-dC
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    5'-O-DMT-N4-Ac-2'-F-dC

    CAS:
    5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.
    Formula:C32H32FN3O7
    Colore e forma:Solid
    Peso molecolare:589.61

    Ref: TM-T37136

  • Viquidacin
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    Viquidacin

    CAS:
    NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.
    Formula:C25H29FN2O4S2
    Colore e forma:Solid
    Peso molecolare:504.64

    Ref: TM-T35064

  • Logo CymitQuimica
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    Deoxythymidine-5'-triphosphate sodium hydrate

    dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.
    Formula:C10H17N2O14P3·xNa·xH2O
    Colore e forma:Solid
    Peso molecolare:C10H17N2O14P3.xNa.xH2O

    Ref: TM-T74122

  • α-Methyl-DL-aspartic acid
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    α-Methyl-DL-aspartic acid

    CAS:
    α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.
    Formula:C5H9NO4
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:147.13

    Ref: TM-T78044

  • 5'-O-DMT-Bz-rC
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    5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C37H35N3O8
    Colore e forma:Solid
    Peso molecolare:649.69

    Ref: TM-T37135

  • CDK2-IN-7
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    CDK2-IN-7

    CAS:
    CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).
    Formula:C24H30N6O4S
    Colore e forma:Solid
    Peso molecolare:498.6

    Ref: TM-T40160

  • [pThr3]-CDK5 Substrate
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    [pThr3]-CDK5 Substrate

    CAS:
    [pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].
    Formula:C53H100N15O15P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1218.43

    Ref: TM-TP1602

  • Logo CymitQuimica
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    2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium

    2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog with extensive antitumor properties, particularly effective
    Formula:C22H43FN7O6P
    Colore e forma:Solid
    Peso molecolare:551.59

    Ref: TM-T75195

  • CDK7-IN-21
    Targetmol
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    CDK7-IN-21

    CAS:
    <p>CDK7-IN-21 (compound A22) is a potent CDK7 inhibitor [1] .</p>
    Formula:C33H36FN9O2
    Colore e forma:Solid
    Peso molecolare:609.7

    Ref: TM-T75121

  • PROTAC CDK9 degrader-11
    Targetmol
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    PROTAC CDK9 degrader-11

    CAS:
    PROTAC CDK9 degrader-11 (Compound C3) is an orally active PROTAC CDK9 degrader with a DC50 of 1.09 nM. This compound exhibits cytotoxicity in small cell lung cancer (SCLC) cells, with IC50 values in the nanomolar range. It induces cell cycle arrest at the G0/G1 phase and inhibits cell invasion in DMS114 and DMS53 cells. In addition, PROTAC CDK9 degrader-11 shows antitumor activity in an NCI-H446 xenograft mouse model. (Pink: ligand for target protein CDK9 ligand 3; Black: linker; Blue: ligand for E3 ligase Cereblon E3 ligase Ligand 56)
    Formula:C39H48Cl2N10O5
    Colore e forma:Solid
    Peso molecolare:807.768

    Ref: TM-T205652

  • Logo CymitQuimica
    Targetmol
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    TC113

    TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.
    Formula:C37H50F2N12O13
    Colore e forma:Solid
    Peso molecolare:908.86

    Ref: TM-T74400

  • Chk1-IN-6
    Targetmol
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    Chk1-IN-6

    CAS:
    <p>Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.</p>
    Formula:C16H18F3N7
    Colore e forma:Solid
    Peso molecolare:365.364

    Ref: TM-T40091

  • WAY-230563
    Targetmol
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    WAY-230563

    CAS:
    <p>WAY-230563 is a serine/threonine kinase inhibitor that blocks CHK1/CHK2-mediated cell cycle checkpoints, leading to G2/M phase arrest in tumour cells</p>
    Formula:C17H12N2O2S
    Purezza:98.40%
    Colore e forma:Solid
    Peso molecolare:308.35

    Ref: TM-T202246