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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3739 prodotti di "Ciclo cellulare/Checkpoint"

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  • WRN inhibitor 17
    Targetmol
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    WRN inhibitor 17

    CAS:
    <p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>
    Formula:C33H34F4N4O6S
    Colore e forma:Solid
    Peso molecolare:690.71

    Ref: TM-T203305

  • MRK-952
    Targetmol
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    MRK-952

    MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.
    Formula:C20H20ClF3N6
    Colore e forma:Solid
    Peso molecolare:436.861

    Ref: TM-T205743

  • Logo CymitQuimica
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    DHFR-IN-8

    DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.
    Formula:C18H14N6S
    Colore e forma:Solid
    Peso molecolare:346.41

    Ref: TM-T79734

  • Logo CymitQuimica
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    PAT-LM1

    PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-1103

  • Logo CymitQuimica
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    GK13S

    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Colore e forma:Solid
    Peso molecolare:390.44

    Ref: TM-T75182

  • Logo CymitQuimica
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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Colore e forma:Solid
    Peso molecolare:563.13

    Ref: TM-T74585

  • Logo CymitQuimica
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    N7-Methyl-2'-O-(2-methoxyethyl) guanosine

    N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.
    Formula:C14H21N5O6
    Colore e forma:Solid
    Peso molecolare:355.35

    Ref: TM-T75060

  • CDK7-IN-5
    Targetmol
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    CDK7-IN-5

    CAS:
    CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).
    Formula:C34H45N9O2
    Colore e forma:Solid
    Peso molecolare:611.795

    Ref: TM-T39247

  • Logo CymitQuimica
    Targetmol
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    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Formula:C36H39ClN4O9S
    Colore e forma:Solid
    Peso molecolare:738.21263

    Ref: TM-T207280

  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
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    HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.
    Formula:C57H62N8O10S
    Colore e forma:Solid
    Peso molecolare:1051.21

    Ref: TM-T74244

  • Clofarabine-5'-diphosphate
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    Clofarabine-5'-diphosphate

    CAS:
    Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.
    Formula:C10H13ClFN5O9P2
    Colore e forma:Solid
    Peso molecolare:463.64

    Ref: TM-T203181

  • Echistatin
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    Echistatin

    CAS:
    Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).
    Formula:C217H341N71O74S9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:5417.1

    Ref: TM-TP2098

  • αVβ8-IN-1
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    αVβ8-IN-1

    CAS:
    <p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>
    Formula:C25H32ClN5O4
    Colore e forma:Solid
    Peso molecolare:502.01

    Ref: TM-T200044

  • Carboxy pyridostatin trifluoroacetate salt
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    Carboxy pyridostatin trifluoroacetate salt

    Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.
    Formula:C37H35F3N10O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:820.73

    Ref: TM-T13595

  • TAS-119
    Targetmol
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    TAS-119

    CAS:
    TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95
    Formula:C23H22Cl2FN5O3
    Purezza:99.65%
    Colore e forma:Solid
    Peso molecolare:506.36

    Ref: TM-T34787

  • CTP Synthetase-IN-1 Ammonium salt
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    CTP Synthetase-IN-1 Ammonium salt

    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:529.56

    Ref: TM-T72505L

  • Stigmatellin
    Targetmol
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    Stigmatellin

    CAS:
    <p>Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.</p>
    Formula:C30H42O7
    Colore e forma:Solid
    Peso molecolare:514.65

    Ref: TM-TN8168

  • SMS 121
    Targetmol
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    SMS 121

    CAS:
    SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.
    Formula:C20H21NO5
    Purezza:98.29%
    Colore e forma:Soild
    Peso molecolare:355.38

    Ref: TM-T205876

  • Logo CymitQuimica
    Targetmol
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    Anti-EMMPRIN/CD147 Antibody

    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-803

  • 11H-Benzo[a]carbazole
    Targetmol
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    11H-Benzo[a]carbazole

    CAS:
    11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.
    Formula:C16H11N
    Purezza:99.14%
    Colore e forma:Solid
    Peso molecolare:217.27

    Ref: TM-TN9686