Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(545 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(249 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(124 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3858 prodotti di "Ciclo cellulare/Checkpoint"
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SJB2-043
CAS:SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).Formula:C17H9NO3Purezza:98.44%Colore e forma:SolidPeso molecolare:275.26HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purezza:99.96%Colore e forma:SolidPeso molecolare:263.29WEE1-IN-3
CAS:WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.Formula:C28H31N7O2Purezza:98.33%Colore e forma:SolidPeso molecolare:497.59Ref: TM-T8916
1mg70,00€5mg156,00€10mg239,00€25mg419,00€50mg562,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€5'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Formula:C9H12FN3O4Purezza:99.67%Colore e forma:White SolidPeso molecolare:245.21TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purezza:98.98%Colore e forma:SolidPeso molecolare:474.33Ref: TM-T5310
1mg50,00€5mg99,00€10mg152,00€25mg245,00€50mg353,00€100mg492,00€200mg700,00€1mL*10mM (DMSO)102,00€Protein kinase inhibitors 1
CAS:Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.Formula:C18H17N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:383.42NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formula:C17H19Cl2N5O4SPurezza:99.56% - 99.85%Colore e forma:SolidPeso molecolare:460.33Ref: TM-TQ0068
1mg46,00€5mg92,00€10mg138,00€25mg255,00€50mg374,00€100mg533,00€200mg705,00€1mL*10mM (DMSO)94,00€AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purezza:97.84% - >99.99%Colore e forma:SolidPeso molecolare:452.55GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Formula:C24H30Cl3N3OColore e forma:SolidPeso molecolare:482.87CeMMEC13
CAS:CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).Formula:C19H16N2O4Purezza:98.52%Colore e forma:SolidPeso molecolare:336.34Ref: TM-T6801
1mg34,00€2mg44,00€5mg66,00€10mg105,00€25mg230,00€50mg334,00€100mg447,00€1mL*10mM (DMSO)73,00€L189
CAS:L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).Formula:C11H10N4OSPurezza:97.37%Colore e forma:SolidPeso molecolare:246.29Bredinin aglycone
CAS:Bredinin aglycone (SM-108) is a purine nucleotide analog.Formula:C4H5N3O2Purezza:99.06%Colore e forma:SolidPeso molecolare:127.1Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.
Formula:C18H22BrN5O3Purezza:98.86% - 99.87%Colore e forma:SolidPeso molecolare:436.3Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.
Formula:C10H14N2Na3O14P3Purezza:99.78%Colore e forma:White Amorphous PowderPeso molecolare:548.11LDN-192960
CAS:LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).Formula:C18H20N2O2SPurezza:99.01% - 99.51%Colore e forma:SolidPeso molecolare:328.43Ref: TM-TQ0111
1mg49,00€2mg64,00€5mg92,00€10mg152,00€25mg295,00€50mg477,00€100mg763,00€200mg1.018,00€1mL*10mM (DMSO)104,00€IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purezza:98.26% - 99.83%Colore e forma:SolidPeso molecolare:473.88Ref: TM-T8842
1mg138,00€5mg295,00€10mg505,00€25mg733,00€50mg888,00€100mg1.251,00€1mL*10mM (DMSO)309,00€TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formula:C9H2Cl4O2Purezza:99.34%Colore e forma:SolidPeso molecolare:283.92Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formula:C27H26N6OPurezza:99.67%Colore e forma:SolidPeso molecolare:450.53Ref: TM-T8430
1mg92,00€5mg178,00€10mg260,00€25mg401,00€50mg532,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)203,00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurezza:>99.99%Colore e forma:SolidPeso molecolare:405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€1mL*10mM (DMSO)286,00€CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:358.67Ref: TM-T19913
1mg73,00€5mg128,00€10mg185,00€25mg299,00€50mg405,00€100mg545,00€1mL*10mM (DMSO)140,00€
