Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(543 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(47 prodotti)
- DYRK(48 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(229 prodotti)
- Chinesina(88 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(119 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
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Trovati 3828 prodotti di "Ciclo cellulare/Checkpoint"
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5-Methyl-5,6-dihydrouridine
CAS:5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.Formula:C10H16N2O6Purezza:98%Colore e forma:SolidPeso molecolare:260.24VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurezza:99.24% - 99.93%Colore e forma:SoildPeso molecolare:437.46Ref: TM-T85309
1mg69,00€5mg147,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€1mL*10mM (DMSO)164,00€GSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formula:C31H30F4N4O5SPurezza:99.141%Colore e forma:SoildPeso molecolare:646.65Vatelizumab
CAS:Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Purezza:95%Colore e forma:LiquidPOSH-IN-1
CAS:POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Formula:C14H8FNO3SPurezza:99.29%Colore e forma:SolidPeso molecolare:289.28Metribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Formula:C8H14N4OSPurezza:99.07%Colore e forma:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecolare:214.29Anti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationPurezza:99%Colore e forma:Odour LiquidViltolarsen
CAS:Viltolarsen targets exon 53 in the dystrophin gene for Duchenne muscular dystrophy research.Colore e forma:SolidN6-Etheno 2'-deoxyadenosine
CAS:N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.Formula:C12H13N5O3Purezza:98%Colore e forma:SolidPeso molecolare:275.26Locked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Formula:C32H32N2O8Purezza:98%Colore e forma:SolidPeso molecolare:572.61DHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].
Formula:C18H16N2O3S2Colore e forma:SolidPeso molecolare:372.46RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Colore e forma:SolidPeso molecolare:287.36hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formula:C19H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:304.349Adenosine 2'-PEG-Biotin
CAS:Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.Formula:C26H40N8O8SColore e forma:SolidPeso molecolare:624.71E-982
CAS:E-982 is derived from the reference compound.Formula:C25H31NO6SPurezza:98%Colore e forma:SolidPeso molecolare:473.58MC-1-F2
CAS:MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity and inhibits cancer stem cell (CSC) properties and can be used to study prostate cancer.Formula:C37H46N16O2Purezza:97.31% - 98.44%Colore e forma:SolidPeso molecolare:746.872'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Formula:C9H11N5O5Purezza:98%Colore e forma:SolidPeso molecolare:269.21(R)-(+)-O-Demethylbuchenavianine
CAS:(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.40L-Threonolactone
CAS:L-Threonolactone is a Carbohydrate Derivative.Formula:C4H6O4Colore e forma:SolidPeso molecolare:118.09SB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Formula:C22H24F3N3O4Purezza:99.58%Colore e forma:SolidPeso molecolare:451.44
