Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(112 prodotti)
- CDK(528 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(260 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(283 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(77 prodotti)
Mostrare 10 più sottocategorie
Trovati 3768 prodotti di "Ciclo cellulare/Checkpoint"
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ERCC1-XPF-IN-2
CAS:<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formula:C15H13Cl2NO3Purezza:98.21%Colore e forma:SolidPeso molecolare:326.17Ref: TM-T60904
2mg40,00€5mg60,00€10mg96,00€25mg187,00€50mg311,00€100mg472,00€200mg658,00€500mg1.026,00€Cytembena
CAS:Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Formula:C11H8BrNaO4Purezza:99.7%Colore e forma:White PowderPeso molecolare:307.07D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formula:C23H36N6SPurezza:99.65%Colore e forma:SolidPeso molecolare:428.64Ref: TM-T10936
1mg37,00€5mg77,00€10mg126,00€25mg250,00€50mg373,00€100mg547,00€200mg777,00€1mL*10mM (DMSO)85,00€Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formula:C22H32N4O4Purezza:98.76%Colore e forma:SolidPeso molecolare:416.51SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purezza:99.54%Colore e forma:SolidPeso molecolare:378.38Ref: TM-T23321
1mg42,00€5mg87,00€10mg130,00€25mg264,00€50mg416,00€100mg652,00€200mg924,00€1mL*10mM (DMSO)72,00€DIF-3
CAS:DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Formula:C13H17ClO4Purezza:99.57%Colore e forma:SolidPeso molecolare:272.72Ref: TM-T60485
1mg92,00€5mg235,00€10mg350,00€25mg588,00€50mg838,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)215,00€9-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formula:C17H22N6OPurezza:99.82%Colore e forma:SolidPeso molecolare:326.4Ref: TM-T23589
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)642,00€Abemaciclib metabolite M20
CAS:Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。Formula:C27H32F2N8OPurezza:98.1% - 99.08%Colore e forma:SolidPeso molecolare:522.59PS423
CAS:PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.Formula:C25H23F3O9Purezza:98.81% - 99.26%Colore e forma:SolidPeso molecolare:524.44ITX3
CAS:ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Formula:C22H17N3OSPurezza:97.28%Colore e forma:SolidPeso molecolare:371.45GS-6620 PM
CAS:GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.Formula:C13H15N5O4Purezza:98.52% - 98.7%Colore e forma:SolidPeso molecolare:305.29L82
CAS:L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.Formula:C11H8ClN5O4Purezza:98.06% - 98.91%Colore e forma:SolidPeso molecolare:309.67Ref: TM-T60753
5mg70,00€10mg103,00€25mg187,00€50mg298,00€100mg472,00€500mg1.026,00€1mL*10mM (DMSO)77,00€CF-1743
CAS:<p>CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.</p>Formula:C22H26N2O5Purezza:99.6% - 99.79%Colore e forma:SolidPeso molecolare:398.45CHK1-IN-3
CAS:CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Formula:C20H23N9OPurezza:98.78%Colore e forma:SolidPeso molecolare:405.46Ref: TM-T10791
1mg172,00€2mg245,00€5mg393,00€10mg590,00€25mg917,00€50mg1.216,00€100mg1.663,00€200mg2.242,00€1mL*10mM (DMSO)445,00€Ryuvidine
CAS:Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.Formula:C15H12N2O2SPurezza:98.6%Colore e forma:SolidPeso molecolare:284.33SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formula:C24H27N5O2Purezza:99.14%Colore e forma:SolidPeso molecolare:417.5Ref: TM-T73475
1mg111,00€5mg264,00€10mg424,00€25mg838,00€50mg1.035,00€100mg1.396,00€1mL*10mM (DMSO)283,00€CDK4/6/1 Inhibitor
CAS:CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).Formula:C28H30F2N6Purezza:97.25% - 99.72%Colore e forma:SolidPeso molecolare:488.576RK73
CAS:6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).Formula:C13H17N5O2SPurezza:99.91%Colore e forma:SolidPeso molecolare:307.37Ref: TM-T10188
1mg144,00€5mg298,00€10mg510,00€25mg825,00€50mg1.130,00€100mg1.510,00€500mg3.060,00€1mL*10mM (DMSO)328,00€ZIM
CAS:ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Formula:C20H19N3O3Purezza:99.85%Colore e forma:SolidPeso molecolare:349.3810-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Formula:C20H19N7O7Purezza:99.97%Colore e forma:SolidPeso molecolare:469.41
