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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3726 prodotti di "Ciclo cellulare/Checkpoint"

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  • NRTT-IN-1
    Targetmol
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    NRTT-IN-1

    CAS:
    <p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>
    Formula:C28H24FN5O5
    Colore e forma:Solid
    Peso molecolare:529.519

    Ref: TM-T205482

  • Aurora A inhibitor 1
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    Aurora A inhibitor 1

    CAS:
    Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)
    Formula:C25H28ClF2N5O2
    Colore e forma:Solid
    Peso molecolare:503.97

    Ref: TM-T63436

  • Logo CymitQuimica
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    Sovesudil hydrochloride

    Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.
    Formula:C23H23ClFN3O3
    Colore e forma:Solid
    Peso molecolare:443.9

    Ref: TM-T62608

  • Zeltociclib
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    Zeltociclib

    CAS:
    <p>Zeltociclib is an inhibitor of cyclin-dependent kinases (CDKs) with anti-tumor properties.</p>
    Formula:C18H20F3N4O2P
    Colore e forma:Solid
    Peso molecolare:412.346

    Ref: TM-T205641

  • Logo CymitQuimica
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    Anticancer agent 29

    <p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>
    Formula:C22H15ClFNO
    Colore e forma:Solid
    Peso molecolare:363.81

    Ref: TM-T61378

  • LNA-AMP
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    LNA-AMP

    CAS:
    LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.
    Formula:C11H14N5O7P
    Colore e forma:Solid
    Peso molecolare:359.23

    Ref: TM-TSW-00964

  • CDK2 degrader 4
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    CDK2 degrader 4

    CAS:
    <p>CDK2 degrader4 (compound 104) is a potent degrader of CDK2, showing promise for cancer research applications.</p>
    Formula:C23H26ClN3O5
    Colore e forma:Solid
    Peso molecolare:459.923

    Ref: TM-T204856

  • WRN inhibitor 13
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    WRN inhibitor 13

    CAS:
    WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.
    Formula:C16H20N2O5S
    Colore e forma:Solid
    Peso molecolare:352.405

    Ref: TM-T204389

  • Logo CymitQuimica
    Targetmol
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    Dyrk1A/B-IN-1

    Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.
    Formula:C21H17N3O2S2
    Colore e forma:Solid
    Peso molecolare:407.51

    Ref: TM-T62043

  • PLK1-IN-5
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    PLK1-IN-5

    CAS:
    PLK1-IN-5, a potent PLK1 inhibitor, has an IC50 of less than 500 nM and demonstrates anticancer effects (WO2008113711A1; compound I-4) [1].
    Formula:C28H39N7O3
    Colore e forma:Solid
    Peso molecolare:521.65

    Ref: TM-T87222

  • GR 122222X
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    GR 122222X

    CAS:
    GR 122222X is an inhibitor of topoisomerase II.
    Formula:C26H35N5O11S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:625.65

    Ref: TM-T24100

  • Z4P
    Targetmol
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    Z4P

    CAS:
    Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.
    Formula:C19H24N2O2
    Purezza:98.99%
    Colore e forma:Solid
    Peso molecolare:312.41

    Ref: TM-T87658

  • CDK2-IN-31
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    CDK2-IN-31

    CAS:
    CDK2-IN-31 (compound I-125A) is an inhibitor of CDK2 and is utilized in cancer research.
    Formula:C37H52N6O5
    Colore e forma:Solid
    Peso molecolare:660.85

    Ref: TM-T201156

  • BRD-7880
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    BRD-7880

    CAS:
    BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.
    Formula:C32H38N4O7
    Colore e forma:Solid
    Peso molecolare:590.67

    Ref: TM-T70600

  • Logo CymitQuimica
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    Antibacterial agent 110

    Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).
    Formula:C22H21N5O4S
    Colore e forma:Solid
    Peso molecolare:451.5

    Ref: TM-T62740

  • Dyrk1A-IN-8
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    Dyrk1A-IN-8

    CAS:
    Dyrk1A-IN-8 is an active molecule that can be used in life science related research. The CAS number of Dyrk1A-IN-8 is 101578-13-6.
    Formula:C17H21N3O
    Colore e forma:Solid
    Peso molecolare:283.37

    Ref: TM-T87614

  • Cdc7-IN-11
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    Cdc7-IN-11

    CAS:
    Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
    Formula:C20H22F2N4O2S
    Colore e forma:Solid
    Peso molecolare:420.48

    Ref: TM-T62231

  • Logo CymitQuimica
    Targetmol
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    MtTMPK-IN-7

    MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.
    Formula:C27H29ClN6O3
    Colore e forma:Solid
    Peso molecolare:521.01

    Ref: TM-T63639

  • DYRK1-IN-1
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    DYRK1-IN-1

    CAS:
    DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.
    Formula:C12H12N6
    Colore e forma:Solid
    Peso molecolare:240.26

    Ref: TM-T60334

  • Elacytarabine
    Targetmol
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    Elacytarabine

    CAS:
    Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
    Formula:C27H45N3O6
    Purezza:97.69%
    Colore e forma:Solid
    Peso molecolare:507.66

    Ref: TM-T15009