Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(541 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(48 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(180 prodotti)
- Integrina(239 prodotti)
- Chinesina(88 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(275 prodotti)
- PKC(117 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(5 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3827 prodotti di "Ciclo cellulare/Checkpoint"
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CDK9 autophagic degrader 1
CAS:CDK9 autophagic degrader 1 (Compound 28) is an ATTEC degrader used to target and degrade CDK9, also impacting the levels of its associated Cyclin T1. At a concentration of 100 nM, it exhibits over 80% inhibition of CDK9.Formula:C34H39N7O4S2Colore e forma:SolidPeso molecolare:673.848(Rac)-Plevitrexed
CAS:(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).Formula:C26H25FN8O4Purezza:98%Colore e forma:SolidPeso molecolare:532.53UM-C162
CAS:UM-C162, a benzimidazole derivative, offers protection to nematodes from Staphylococcus aureus infections. It inhibits biofilm formation without impairing bacterial viability. Additionally, UM-C162 disrupts the production of Staphylococcus aureus hemolysins, proteases, and coagulases. This compound holds potential as an antivirulence agent for managing Staphylococcus aureus infections.Formula:C30H25N3O4Colore e forma:SolidPeso molecolare:491.54Ascofuranone
CAS:Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFormula:C23H29ClO5Colore e forma:SolidPeso molecolare:420.93Aurora inhibitor 1
CAS:Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).Formula:C23H25N9SPurezza:98%Colore e forma:SolidPeso molecolare:459.57GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Formula:C26H35N5O11SPurezza:98%Colore e forma:SolidPeso molecolare:625.6512(S)-HETE
CAS:Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.
Formula:C20H32O3Colore e forma:SolidPeso molecolare:320.47L 734217
CAS:L 734217 is an antagonist of the fibrinogen receptor.Formula:C18H31N3O4Purezza:98%Colore e forma:SolidPeso molecolare:353.462'-O-MOE-GTP
CAS:2'-O-MOE-GTP is a nucleotide analog utilized in the synthesis of oligonucleotides.Formula:C13H22N5O15P3Colore e forma:SolidPeso molecolare:581.26ART615
ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).Formula:C21H21F3N4O2Colore e forma:SolidPeso molecolare:418.41Sovesudil hydrochloride
Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.Formula:C23H23ClFN3O3Colore e forma:SolidPeso molecolare:443.9Dyrk1A-IN-11
CAS:Dyrk1A-IN-11 (compound 166) is an effective inhibitor targeting dual-specificity tyrosine phosphorylation-regulated 1A (DYRK1A) with an EC50 of 0.0021 µM. Additionally, this compound inhibits the phosphorylation of Tau (Thr212) with an EC50 of 0.0361 µM.Formula:C23H23F5N8OColore e forma:SolidPeso molecolare:522.47ROCK-IN-11
CAS:ROCK-IN-11 (example 94) is an effective inhibitor of ROCK1 and ROCK2, with an IC50 of ≤ 5 μM, and plays a significant role in cancer research.Formula:C22H20N4O4SColore e forma:SolidPeso molecolare:436.484Dyrk1A/B-IN-1
Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.Formula:C21H17N3O2S2Colore e forma:SolidPeso molecolare:407.51BRD-7880
CAS:BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.Formula:C32H38N4O7Colore e forma:SolidPeso molecolare:590.672′-F-UDP
CAS:2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.Formula:C9H13FN2O11P2Colore e forma:SolidPeso molecolare:406.15Anti-neuroinflammation agent 3
CAS:Compound A.10.3 (Anti-neuroinflammation agent 3) exhibits inhibitory activity against various Ser/Thr kinases or receptor/non-receptor tyrosine kinases.Formula:C22H23FN6O2Peso molecolare:422.455Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formula:C9H20N2O8Colore e forma:SolidPeso molecolare:284.26MtTMPK-IN-7
MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.Formula:C27H29ClN6O3Colore e forma:SolidPeso molecolare:521.01VCPIP1-IN-1
CAS:VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.Formula:C13H15ClN2O2Purezza:99.3%Colore e forma:SolidPeso molecolare:266.72Ref: TM-T88664
1mg49,00€5mg97,00€10mg154,00€25mg298,00€50mg472,00€100mg755,00€200mg1.017,00€1mL*10mM (DMSO)106,00€
