Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(525 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(180 prodotti)
- Integrina(256 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(283 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(75 prodotti)
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Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"
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(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Formula:C25H34O10Colore e forma:SolidPeso molecolare:494.537MS7131
MS7131 is a DUBTAC inhibitor that recruits USP1. It effectively reduces histone H3 lysine 27 trimethylation and significantly inhibits the proliferation and colony-forming ability of cancer cells.Colore e forma:Odour SolidDNA Gyrase-IN-6
Agent 138: soluble benzothiazole, inhibits DNA gyrase/topoisomerase IV, targets Gram+ & Gram- bacteria, binds plasma proteins.Formula:C18H16Cl2N4O4SColore e forma:SolidPeso molecolare:455.325'-DMTr-3'dA(Bz)-methylphosphonami dite
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoidFormula:C45H51N6O6PColore e forma:SolidPeso molecolare:802.9NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C24H30N6OColore e forma:SolidPeso molecolare:418.535LSN3106729 hydrochloride
CAS:LSN3106729 hydrochloride, an Abemaciclib metabolite, is a CDK-inhibiting antitumor PROTAC CDK4/6 degrader.Formula:C25H29ClF2N8OColore e forma:SoildPeso molecolare:531.00Bz-rC Phosphoramidite
CAS:<p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formula:C52H66N5O9PSiColore e forma:SolidPeso molecolare:964.185WRN inhibitor 17
CAS:WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.Formula:C33H34F4N4O6SColore e forma:SolidPeso molecolare:690.71BIO5192 hydrate
BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.Colore e forma:SolidCarboxy pyridostatin trifluoroacetate salt
Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.Formula:C37H35F3N10O9Purezza:98%Colore e forma:SolidPeso molecolare:820.735'-O-DMT-ibu-dC
CAS:5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.Formula:C34H37N3O7Colore e forma:SolidPeso molecolare:599.67Uridine triphosphate 13C9,15N2 sodium
CAS:Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formula:C9H1415N2NaO15P3Colore e forma:SolidPeso molecolare:517.045'-O-DMT-rU
CAS:5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.Formula:C30H30N2O8Colore e forma:SolidPeso molecolare:546.57WAY-322243
CAS:WAY-322243 has antibacterial and anti-inflammatory activity and has an inhibitory effect on CLK-1, which can be used to study Alzheimer's disease.Formula:C18H18N2O2SPurezza:99.88%Colore e forma:SoildPeso molecolare:326.41m7GpppCpG
CAS:<p>m7GpppCpG, a trinucleotide cap analogue, is used for synthesizing RNA with cap 0 or cap 1 structures.</p>Formula:C30H41N13O25P4Colore e forma:SolidPeso molecolare:1107.61CDK2/PIM1-IN-1
<p>CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.</p>Colore e forma:Odour Solidwrwyar-NH2 TFA
<p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>Colore e forma:Odour Solid5'-O-DMT-2'-O-TBDMS-Bz-rC
CAS:5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is utilized in the synthesis of DNA or RNA.Formula:C43H49N3O8SiColore e forma:SolidPeso molecolare:763.95N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
<p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>Formula:C41H43N3O9Colore e forma:SolidPeso molecolare:721.79Nitrosofolic acid
CAS:<p>Nitrosofolic acid is a folic acid derivaive.</p>Formula:C19H18N8O7Colore e forma:SolidPeso molecolare:470.40
