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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"

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  • Logo CymitQuimica
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    GK13S

    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Colore e forma:Solid
    Peso molecolare:390.44

    Ref: TM-T75182

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    3'-β-C-ethynyl-N6-iso-pentenyl adenosine

    <p>3’-Beta-C-ethynyl-N6-iso-pentenyl adenosine is an adenosine analog.</p>
    Formula:C17H21N5O4
    Colore e forma:Solid
    Peso molecolare:359.38

    Ref: TM-T75049

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    N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine

    <p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H22N2O7
    Colore e forma:Solid
    Peso molecolare:330.33

    Ref: TM-T75214

  • MRK-952
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    MRK-952

    MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.
    Formula:C20H20ClF3N6
    Colore e forma:Solid
    Peso molecolare:436.861

    Ref: TM-T205743

  • Stigmatellin
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    Stigmatellin

    CAS:
    <p>Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.</p>
    Formula:C30H42O7
    Colore e forma:Solid
    Peso molecolare:514.65

    Ref: TM-TN8168

  • c-Myc inhibitor 10
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    c-Myc inhibitor 10

    CAS:
    c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.
    Formula:C28H38N6O3
    Colore e forma:Solid
    Peso molecolare:506.64

    Ref: TM-T75239

  • CDK5-IN-1
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    CDK5-IN-1

    CAS:
    <p>CDK5-IN-1: Potent CDK5 inhibitor (&lt;10 nM) used in kidney disease research.</p>
    Formula:C24H25FN6O3S
    Colore e forma:Solid
    Peso molecolare:496.56

    Ref: TM-T40263

  • Sarecycline hydrochloride
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    Sarecycline hydrochloride

    CAS:
    Sarecycline hydrochloride is a narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity.
    Formula:C24H30ClN3O8
    Purezza:99.23%
    Colore e forma:Solid
    Peso molecolare:523.96

    Ref: TM-T21394

  • SR15006
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    SR15006

    CAS:
    SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
    Formula:C16H20ClN3O4S
    Purezza:99.87%
    Colore e forma:Soild
    Peso molecolare:385.87

    Ref: TM-T60037

  • Remdesivir nucleoside monophosphate
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    Remdesivir nucleoside monophosphate

    CAS:
    Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.
    Formula:C12H14N5O7P
    Colore e forma:Solid
    Peso molecolare:371.24

    Ref: TM-T39334

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    Etrolizumab

    CAS:
    MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.
    Purezza:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)
    Colore e forma:Liquid

    Ref: TM-T77154

  • UCK2 Inhibitor-3
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    UCK2 Inhibitor-3

    CAS:
    UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.
    Formula:C19H13BrFN5O2S
    Colore e forma:Solid
    Peso molecolare:474.31

    Ref: TM-T72696

  • CDK9 inhibitor HH1
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    CDK9 inhibitor HH1

    CAS:
    <p>CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.</p>
    Formula:C13H15N3OS
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:261.34

    Ref: TM-T118066

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    CBP-501 acetate

    CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a candidate G2 phase checkpoint abrogator. It inhibits several Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2, with IC50 values of 0.9 μM, 1.4 μM, 3.4 μM, and 6.5 μM, respectively. CBP-501 acetate is applicable to various cancer research studies.
    Colore e forma:Odour Solid

    Ref: TM-TP3244

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    PKMYT1-IN-3

    PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.
    Formula:C24H26FN5O2
    Colore e forma:Solid
    Peso molecolare:435.49

    Ref: TM-T200211

  • Rifalazil
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    Rifalazil

    CAS:
    Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.
    Formula:C51H64N4O13
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:941.07

    Ref: TM-T16749

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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Colore e forma:Solid
    Peso molecolare:563.13

    Ref: TM-T74585

  • Purine riboside triphosphate
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    Purine riboside triphosphate

    CAS:
    Purine riboside triphosphate resembles adenosine; inhibits cancer cell growth by blocking RNA/DNA synthesis.
    Formula:C10H15N4O13P3
    Colore e forma:Solid
    Peso molecolare:492.17

    Ref: TM-T39856

  • AB-3PRGD2
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    AB-3PRGD2

    CAS:
    <p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>
    Formula:C137H215IN30O45S
    Colore e forma:Solid
    Peso molecolare:3161.32

    Ref: TM-T206427

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    UnyLinker 12 TEA

    UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.
    Formula:C39H35NO10C6H15N
    Colore e forma:Solid
    Peso molecolare:778.34655

    Ref: TM-TSW-00947