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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3739 prodotti di "Ciclo cellulare/Checkpoint"

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  • 3'-β-C-Methyl-2-thiouridine


    3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.
    Formula:C10H14N2O5S
    Colore e forma:Solid
    Peso molecolare:274.29
  • USP7-IN-15


    USP7-IN-15 (compound J21) is an inhibitor of USP7, exhibiting an IC50 value of 41.35 ± 2.16 nM.
    Colore e forma:Odour Solid
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Colore e forma:Solid
    Peso molecolare:687.74
  • 6-Thioguanosine

    CAS:
    6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.
    Formula:C10H13N5O4S
    Purezza:97.05%
    Colore e forma:Yellow-Green Powder
    Peso molecolare:299.31
  • ROCK-IN-32

    CAS:
    ROCK-IN-32 is an effective Rho-kinase inhibitor.
    Formula:C20H17Cl2N3O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:402.27
  • Thailanstatin C

    CAS:
    Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.
    Formula:C30H46ClNO9
    Colore e forma:Solid
    Peso molecolare:600.15
  • CDK12-IN-6

    CAS:
    CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).
    Formula:C20H21F2N9
    Colore e forma:Solid
    Peso molecolare:425.448
  • Hemsloside Ma 1

    CAS:
    Hemsloside Ma 1 is a useful organic compound for research related to life sciences. The catalog number is T123850 and the CAS number is 95851-41-5.
    Formula:C47H74O18
    Colore e forma:Solid
    Peso molecolare:927.091
  • Chk1-IN-6

    CAS:
    <p>Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.</p>
    Formula:C16H18F3N7
    Colore e forma:Solid
    Peso molecolare:365.364
  • Uridine triphosphate 13C9,15N2 sodium

    CAS:
    Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.
    Formula:C9H1415N2NaO15P3
    Colore e forma:Solid
    Peso molecolare:517.04
  • CBR-2092

    CAS:
    CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.
    Formula:C65H81FN6O15
    Colore e forma:Solid
    Peso molecolare:1205.388
  • Etrolizumab

    CAS:
    MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.
    Purezza:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)
    Colore e forma:Liquid
  • Centaureidin

    CAS:
    <p>Centaureidin is a useful organic compound for research related to life sciences. The catalog number is T125588 and the CAS number is 17313-52-9.</p>
    Formula:C18H16O8
    Colore e forma:Solid
    Peso molecolare:360.318
  • Psammaplin A

    CAS:
    <p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>
    Formula:C22H24Br2N4O6S2
    Colore e forma:Solid
    Peso molecolare:664.38
  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.
    Formula:C10H14N5Na2O8P
    Colore e forma:Solid
    Peso molecolare:409.202
  • DSPE-PEG1000-cRGD


    DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.
    Colore e forma:Odour Solid
  • CDK9-IN-25


    <p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>
    Formula:C15H16FN5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:285.32
  • AG2034

    CAS:
    AG2034 is an inhibitor of the glycinamide ribonucleotide formyltransferase (GARFT).
    Formula:C18H21N5O6S2
    Colore e forma:Solid
    Peso molecolare:467.52
  • Ficellomycin

    CAS:
    Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.
    Formula:C13H24N6O3
    Colore e forma:Solid
    Peso molecolare:312.37
  • 5'-O-DMT-rI

    CAS:
    5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].
    Formula:C31H30N4O7
    Colore e forma:Solid
    Peso molecolare:570.59