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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3730 prodotti di "Ciclo cellulare/Checkpoint"

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  • Logo CymitQuimica
    Targetmol
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    CD532 hydrochloride

    CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.
    Colore e forma:Solid

    Ref: TM-T36932

  • Remdesivir nucleoside monophosphate
    Targetmol
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    Remdesivir nucleoside monophosphate

    CAS:
    Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.
    Formula:C12H14N5O7P
    Colore e forma:Solid
    Peso molecolare:371.24

    Ref: TM-T39334

  • JAMM protein inhibitor 2 
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    JAMM protein inhibitor 2 

    CAS:
    JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.
    Formula:C21H26N2O2
    Purezza:98.57%
    Colore e forma:Solid
    Peso molecolare:338.44

    Ref: TM-T9892

  • CDK5-IN-1
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    CDK5-IN-1

    CAS:
    <p>CDK5-IN-1: Potent CDK5 inhibitor (&lt;10 nM) used in kidney disease research.</p>
    Formula:C24H25FN6O3S
    Colore e forma:Solid
    Peso molecolare:496.56

    Ref: TM-T40263

  • SNX7
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    SNX7

    CAS:
    SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.
    Formula:C15H14N2O
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:238.28

    Ref: TM-T77613

  • Heliquinomycin
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    Heliquinomycin

    CAS:
    Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.
    Formula:C33H30O17
    Colore e forma:Solid
    Peso molecolare:698.586

    Ref: TM-T36748

  • (S)-DI-87
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    (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purezza:99.42%
    Colore e forma:Soild
    Peso molecolare:502.65

    Ref: TM-T39550L

  • (E/Z)-THZ1 2HCl
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    (E/Z)-THZ1 2HCl

    CAS:
    <p>THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.</p>
    Formula:C31H30Cl3N7O2
    Purezza:99.51%
    Colore e forma:Solid
    Peso molecolare:638.98

    Ref: TM-T35332

  • MRK-952
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    MRK-952

    MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.
    Formula:C20H20ClF3N6
    Colore e forma:Solid
    Peso molecolare:436.861

    Ref: TM-T205743

  • Gantofiban
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    Gantofiban

    CAS:
    Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
    Formula:C21H29N5O6
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:447.48

    Ref: TM-T68078

  • Logo CymitQuimica
    Targetmol
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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Colore e forma:Solid
    Peso molecolare:563.13

    Ref: TM-T74585

  • Logo CymitQuimica
    Targetmol
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    Antibacterial agent 144

    Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.
    Formula:C26H23N7O3
    Colore e forma:Solid
    Peso molecolare:481.51

    Ref: TM-T79282

  • AB-3PRGD2
    Targetmol
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    AB-3PRGD2

    CAS:
    <p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>
    Formula:C137H215IN30O45S
    Colore e forma:Solid
    Peso molecolare:3161.32

    Ref: TM-T206427

  • Logo CymitQuimica
    Targetmol
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    STX-100

    PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.
    Purezza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-062

  • Logo CymitQuimica
    Targetmol
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    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Formula:C36H39ClN4O9S
    Colore e forma:Solid
    Peso molecolare:738.21263

    Ref: TM-T207280

  • Logo CymitQuimica
    Targetmol
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    Chrexanthomycin C

    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Colore e forma:Solid
    Peso molecolare:636.51

    Ref: TM-T75527

  • CDK6/9-IN-1
    Targetmol
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    CDK6/9-IN-1

    CAS:
    <p>CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).</p>
    Formula:C22H25ClN8O
    Colore e forma:Solid
    Peso molecolare:452.95

    Ref: TM-T40047

  • α2β1 Integrin Ligand Peptide
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    α2β1 Integrin Ligand Peptide

    CAS:
    The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular
    Formula:C14H22N4O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:390.35

    Ref: TM-TP1484

  • Logo CymitQuimica
    Targetmol
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    N7-Methyl-2'-O-(2-methoxyethyl) guanosine

    N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.
    Formula:C14H21N5O6
    Colore e forma:Solid
    Peso molecolare:355.35

    Ref: TM-T75060

  • Barasertib
    Targetmol
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    Barasertib

    CAS:
    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
    Formula:C26H31FN7O6P
    Purezza:99.92% - 99.97%
    Colore e forma:Solid
    Peso molecolare:587.54

    Ref: TM-T14371