Trasportatore di membrana/canale ionico
Gli inibitori dei trasportatori di membrana e dei canali ionici sono composti che bloccano la funzione delle proteine responsabili del trasporto di ioni, nutrienti e altre molecole attraverso le membrane cellulari. Questi inibitori sono cruciali per studiare la regolazione dell'omeostasi cellulare, la trasduzione del segnale e la neurotrasmissione. Gli inibitori dei trasportatori di membrana e dei canali ionici sono anche importanti per sviluppare trattamenti per disturbi come l'epilessia, le malattie cardiovascolari e le sindromi metaboliche. Presso CymitQuimica, offriamo una vasta selezione di inibitori di alta qualità dei trasportatori di membrana e dei canali ionici per supportare la tua ricerca in fisiologia, neuroscienze e farmacologia.
Sottocategorie di "Trasportatore di membrana/canale ionico"
- ABC(3 prodotti)
- ATPasi(101 prodotti)
- Recettore dell'adiponectina(5 prodotti)
- CFTR(65 prodotti)
- Ricettore CGRP(54 prodotti)
- Canale del calcio(541 prodotti)
- Canale del cloruro(53 prodotti)
- Ricettore GABA(365 prodotti)
- Trasportatore di monoammine(30 prodotti)
- Trasportatore di monocarbossilato(18 prodotti)
- NKCC(2 prodotti)
- NPC1L1(3 prodotti)
- Cotrasportatore Na-K-Cl(10 prodotti)
- OAT(32 prodotti)
- OCT(7 prodotti)
- P-gp(55 prodotti)
- Canale del potassio(280 prodotti)
- Pompa protonica(42 prodotti)
- SGLT(31 prodotti)
- Canale del sodio(209 prodotti)
- Canale TRP/TRPV(96 prodotti)
Mostrare 13 più sottocategorie
Trovati 2521 prodotti di "Trasportatore di membrana/canale ionico"
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Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formula:C29H32N2O6SPurezza:98.58% - 99.01%Colore e forma:SolidPeso molecolare:536.64Caged MK801
CAS:Caged MK801 (cMK801) is a selective, noncompetitive, and irreversible blocker of the NMDA receptor open channel. The NVOC cage is compatible in neuropharmacology and does not alter the intrinsic activity of the molecule.Formula:C26H24N2O6Colore e forma:SolidPeso molecolare:460.48S 0960
CAS:S 0960 is a dimeric bile acid analogue, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.Formula:C48H79NO8Purezza:99.32% - >99.99%Colore e forma:SolidPeso molecolare:798.14ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Formula:C29H25N3O4SColore e forma:SolidPeso molecolare:511.59IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Formula:C16H13F6NO2Colore e forma:SolidPeso molecolare:365.27CRM1-IN-3
CAS:<p>CRM1-IN-3 (B28), a noncovalent inhibitor of CRM1, is utilized in the research of protein localization and tumor studies [1].</p>Formula:C26H26ClN3O3Colore e forma:SolidPeso molecolare:463.96Blixeprodil
CAS:Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.Formula:C13H16FNOColore e forma:SolidPeso molecolare:221.271Sp-8-Br-cGMPS
CAS:Sp-8-Br-cGMPS, an analogue of cGMP, acts as an agonist for cGMP gated cation channels (CNG channels) with an EC50 of 106.5 μM. While Sp-8-Br-cGMPS can induce currents, it does not stabilize channel open states as effectively as a full agonist.Formula:C10H11BrN5O6PSColore e forma:SolidPeso molecolare:440.17P2X4-IN-1
CAS:P2X4-IN-1 is an orally active P2X4 inhibitor. P2X4-IN-1 is applicable in research focused on disease prevention.Formula:C18H14ClN5O3SColore e forma:SolidPeso molecolare:415.85PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formula:C18H23N3O3Purezza:98%Colore e forma:SolidPeso molecolare:329.39CFTR corrector 18
CAS:CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).Formula:C38H40N6O5SColore e forma:SolidPeso molecolare:692.8262-PPA
CAS:2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.Formula:C11H10N2Colore e forma:SolidPeso molecolare:170.21BMS-986163
CAS:BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).Formula:C23H28FN2O5PPurezza:98%Colore e forma:SolidPeso molecolare:462.45264W94
CAS:264W94 robustly inhibits IBAT, induces CYP7A1, and significantly reduces cholesterol.Formula:C23H31NO4SPurezza:98%Colore e forma:SolidPeso molecolare:417.56ATP synthase inhibitor 2
CAS:ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.Formula:C21H22N2O3SColore e forma:SolidPeso molecolare:382.48TRPV1 antagonist 10
CAS:TRPV1 antagonist 10 is a potent, orally active TRPV1 antagonist with an IC50 of 33.06 nM and serves as a moderate to weak inhibitor of URAT1 (IC50 = 22.51 μM) and GLUT9 (inhibition of 60.25% at 50 μM). It exhibits analgesic and urate-lowering properties and is applicable for research in hyperuricemia and inflammatory pain.Formula:C16H14N2O5Colore e forma:SolidPeso molecolare:314.293NMDA receptor antagonist-3
NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.Formula:C13H19N3O6Colore e forma:SolidPeso molecolare:313.31T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColore e forma:SolidPeso molecolare:594.788-Prenylchrysin
CAS:8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.Formula:C20H18O4Colore e forma:SolidPeso molecolare:322.354SR 33805 oxalate
CAS:Ca2+ channel antagonistFormula:C34H42N2O9SPurezza:98%Colore e forma:SolidPeso molecolare:654.77
