Adattatori Tirosin-chinasi
Gli inibitori delle tirosine chinasi e degli adattatori sono composti che bersagliano le tirosine chinasi e le loro proteine adattatrici associate, che svolgono ruoli cruciali nella segnalazione cellulare, nella crescita e nella differenziazione. Questi inibitori sono strumenti essenziali nella ricerca sul cancro, poiché molte tirosine chinasi sono coinvolte nelle vie di segnalazione che promuovono la crescita e la metastasi tumorale. Inibendo le tirosine chinasi, questi composti possono bloccare cascate di segnalazione critiche, offrendo potenziali strategie terapeutiche per vari tipi di cancro e altre malattie che coinvolgono una segnalazione cellulare anomala. Presso CymitQuimica, offriamo una vasta gamma di inibitori di tirosine chinasi e adattatori di alta qualità per supportare la tua ricerca in oncologia, biologia molecolare e sviluppo di terapie mirate.
Sottocategorie di "Adattatori Tirosin-chinasi"
- ALK(133 prodotti)
- CSF-1R(42 prodotti)
- EGFR(591 prodotti)
- Recettore di Ephrin(25 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(182 prodotti)
- HER(3 prodotti)
- Hck(3 prodotti)
- IGF-1R(104 prodotti)
- PDGFR(129 prodotti)
- PYK2(7 prodotti)
- Src(82 prodotti)
- Ricettore TAM(34 prodotti)
- Tie-2(20 prodotti)
- Recettore Trk(57 prodotti)
- Tirosin-chinasi(24 prodotti)
- VEGFR(245 prodotti)
- c-Fms(112 prodotti)
- c-Kit(116 prodotti)
- c-Met/HGFR(139 prodotti)
- c-RET(61 prodotti)
Mostrare 13 più sottocategorie
Trovati 1135 prodotti di "Adattatori Tirosin-chinasi"
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MerTK-IN-3
CAS:MerTK-IN-3 (compound 11) is an orally active, selective inhibitor of MerTK, exhibiting IC50 values of 21.5 nM for MerTK and 991.3 nM for Tyro3. It is applicable in colon cancer research.Formula:C36H31FN8O4Colore e forma:SolidPeso molecolare:658.68EGFR-IN-48
EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants & BaF3/PC-9 cell proliferation.Colore e forma:SolidLSD1/EGFR-IN-1
CAS:LSD1/EGFR-IN-1 (compound L-1) is an effective inhibitor of LSD1, EGFRT790M/L858R, and EGFRL858R/T790M/C797S, with IC50 values of 6.24, 2.06, and 5.01 μM, respectively. This compound plays a significant role in cancer research.
Formula:C21H20ClN3O4Colore e forma:SolidPeso molecolare:413.854EGFR/HER2-IN-7
EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.Formula:C19H21N3O2SColore e forma:SolidPeso molecolare:355.45EGFR/HER2-IN-5
EGFR/HER2-IN-5: Irreversible, oral dual EGFR inhibitor, IC50 0.6 nM, targets L858R/T790M mutations, anti-tumor in vivo for lung cancer study.Colore e forma:SolidITK inhibitor 2
CAS:ITK inhibitor 2 (compound 4) is a potent and selective ITK inhibitor with an IC50= 2 nM.Formula:C25H33N5O2Purezza:99.67%Colore e forma:SolidPeso molecolare:435.56HER2-IN-7
CAS:HER2-IN-7 is a potent HER2 inhibitor with potential for researching ErbB-related diseases, especially cancer.Formula:C28H26F3N7O3Colore e forma:SolidPeso molecolare:565.55EGFR-IN-58
EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.Formula:C31H30FN7OColore e forma:SolidPeso molecolare:535.61EGFR-IN-125
CAS:EGFR-IN-125 (example 37) is a potent EGFR inhibitor with IC50 values of <0.3 nM for EGFR(d746-750/T790M/C797S), 0.52 nM for EGFR(L858R/T790M/C797S), 0.5 nM for EGFR(d746-750/C797S), 0.69 nM for EGFR(L858R/C797S), and 0.92 nM for EGFR (wild type).Formula:C30H26N8OColore e forma:SolidPeso molecolare:514.58EGFR-IN-38
CAS:EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.Formula:C25H24ClN7O2Colore e forma:SolidPeso molecolare:489.96AZ12601011
CAS:AZ12601011 is a TGFBR1 kinase inhibitor that inhibits the growth of breast tumors.Formula:C19H15N5Purezza:98.81%Colore e forma:SolidPeso molecolare:313.36Ref: TM-T10426
1mg99,00€5mg235,00€10mg376,00€25mg728,00€50mg1.093,00€100mg1.510,00€1mL*10mM (DMSO)259,00€Vecabrutinib
CAS:Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.
Formula:C22H24ClF4N7O2Purezza:99.74%Colore e forma:SolidPeso molecolare:529.92Zotizalkib
CAS:TPX-0131: potent, selective, CNS-ready, oral ALK inhibitor (WT IC50: 1.4nM, G1202R/L1196M IC50: 0.3nM) with robust antitumor effects.Formula:C21H20F3N5O3Purezza:98.7%Colore e forma:SolidPeso molecolare:447.41Ref: TM-T9414
1mg120,00€5mg283,00€10mg464,00€25mg929,00€50mg1.473,00€100mg1.977,00€200mg2.802,00€1mL*10mM (DMSO)319,00€AGL-2263
CAS:AGL-2263 is a blocker of insulin receptor (IR)Formula:C17H10N2O5Colore e forma:SolidPeso molecolare:322.27EGFR-IN-7
CAS:EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.
Formula:C32H41BrN9O2PPurezza:95.32% - 99.64%Colore e forma:SolidPeso molecolare:694.6Nimotuzumab (powder)
CAS:Nimotuzumab (powder) is a humanized IgG1 monoclonal antibody that specifically targets the epidermal growth factor receptor (EGFR), possessing a dissociation constant (KD) of 0.21 nM. It blocks the binding to its ligand by targeting the extracellular domain of EGFR. Nimotuzumab exhibits strong antitumor activity by inducing both antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), exerting cytolytic effects on target tumors.
Colore e forma:LiquidHMBD-001
HMBD-001 is a humanized IgG1 monoclonal antibody inhibitor that targets HER3. By inhibiting the dimerization of HER3, HMBD-001 suppresses the growth and proliferation of tumor cells. It holds potential for research in cancer treatments, specifically for pancreatic cancer and non-small cell lung cancer.
Colore e forma:Odour LiquidImbotolimod
Imbotolimod, a humanized monoclonal antibody of the immunoglobulin G1-kappa class, exhibits both anti-ERBB2 and antineoplastic activities.Colore e forma:Odour LiquidTLC9995-0188
CAS:Tyrosine-protein kinase ABL, IC50: 1500 nMFormula:C16H15N5Colore e forma:Yellow SolidPeso molecolare:277.331Tyrosine kinase inhibitor
CAS:Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents.Formula:C31H31FN6O5Purezza:98%Colore e forma:SolidPeso molecolare:586.61
