Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.003 prodotti)
- Recettore dell'adenosina(247 prodotti)
- Recettore adrenergico(3.010 prodotti)
- Recettore della bombesina(33 prodotti)
- Recettore della bradichinina(60 prodotti)
- CXCR(153 prodotti)
- CaSR(33 prodotti)
- Recettore dei cannabinoidi(215 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(435 prodotti)
- Recettore dell'endotelina(83 prodotti)
- Recettore GNRH(82 prodotti)
- GPCR19(33 prodotti)
- GRK(32 prodotti)
- GTPase(22 prodotti)
- Recettore del glucagone(190 prodotti)
- Proteina Hedgehog/Smoothened(48 prodotti)
- Recettore dell'istamina(381 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(321 prodotti)
- PAFR(13 prodotti)
- PKA(51 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 19 più sottocategorie
Trovati 5838 prodotti di "Proteina G/GPCR"
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Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColore e forma:SolidPeso molecolare:303.83Bevantolol hydrochloride
CAS:Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.Formula:C20H28ClNO4Purezza:99.49%Colore e forma:SolidPeso molecolare:381.9Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Formula:C20H25FN4OPurezza:99.56%Colore e forma:SolidPeso molecolare:356.44Dobutamine tartrate
CAS:Dobutamine tartrate is a cardiotonic.Formula:C22H29NO9Colore e forma:SolidPeso molecolare:451.472Bimatoprost
CAS:<p>Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular</p>Formula:C25H37NO4Purezza:98% - >99.99%Colore e forma:Crystalline SolidPeso molecolare:415.57Fluorogestone acetate
CAS:FGA (Fluorogestone Acetate, SC9880) is 20-25x more potent than progesterone with high potency and short activity duration.Formula:C23H31FO5Purezza:99.47%Colore e forma:CoaPeso molecolare:406.49Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Formula:C8H10N4O2Purezza:98.37%Colore e forma:SolidPeso molecolare:194.19Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Formula:C22H28FNO3Purezza:98.94% - 99.95%Colore e forma:SolidPeso molecolare:373.46Obestatin (rat) acetate
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39).Formula:C114H174N34O31Purezza:99.05%Colore e forma:SolidPeso molecolare:2516.81Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Formula:C27H34ClNO4Colore e forma:SolidPeso molecolare:472.02Relugolix
CAS:Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, withFormula:C29H27F2N7O5SPurezza:98.64% - 99.97%Colore e forma:SolidPeso molecolare:623.63PF-06882961 Tris
CAS:PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.Formula:C35H41FN6O7Purezza:98.74% - 99.79%Colore e forma:SolidPeso molecolare:676.7Olcegepant
CAS:Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Formula:C38H47Br2N9O5Purezza:96.08% - 97.24%Colore e forma:SolidPeso molecolare:869.65Eprazinone
CAS:Erazinone is a mucus dissolver and bronchospasm reliever.Formula:C24H32N2O2Colore e forma:SolidPeso molecolare:380.52Laropiprant sodium
<p>Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM for TP receptors and 2.95 nM for DP receptors.</p>Colore e forma:SolidBupranolol
CAS:Bupranolol blocks β2-adrenergic receptor; treats angina, hypertension, glaucoma, arrhythmia, and prevents clots.Formula:C14H22ClNO2Purezza:97.63%Colore e forma:SolidPeso molecolare:271.78Elagolix sodium
CAS:<p>Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).</p>Formula:C32H29F5N3NaO5Purezza:99.71%Colore e forma:SolidPeso molecolare:653.57Pasireotide Acetate
CAS:The pKi of Pasireotide (SOM230) acetate for sst1, 2, 3, 4, and 5 were 8.2, 9.0, 9.1, less than 7.0, and 9.9, respectively.Cost-effective and quality-assured.Formula:C60H70N10O11Purezza:98.64% - 99.92%Colore e forma:SolidPeso molecolare:1107.26H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFormula:C21H12N2O7Purezza:98.25% - 99.47%Colore e forma:SolidPeso molecolare:404.33Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Formula:C24H30N2O2SPurezza:99.9% - 99.92%Colore e forma:SolidPeso molecolare:410.57Quipazine maleate
CAS:Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.Formula:C17H19N3O4Colore e forma:SolidPeso molecolare:329.356Fluoroclebopride
CAS:Fluoroclebopride is a dopamine (DA) D2 receptor ligand.Formula:C20H23ClFN3O2Purezza:99.68% - 99.91%Colore e forma:SolidPeso molecolare:391.87Carbazochrome
CAS:<p>Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.</p>Formula:C10H12N4O3Purezza:98.36%Colore e forma:Nacarat Crystalline PowderPeso molecolare:236.23RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purezza:98.64% - 99.62%Colore e forma:SolidPeso molecolare:417.5PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purezza:98.85% - 99.47%Colore e forma:SolidPeso molecolare:568.59Ciliobrevin A
CAS:<p>Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.</p>Formula:C17H9Cl2N3O2Purezza:98.54% - 99.57%Colore e forma:SolidPeso molecolare:358.18SANT-1
CAS:SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).Formula:C23H27N5Purezza:99.93% - >99.99%Colore e forma:SolidPeso molecolare:373.49ML221
CAS:<p>ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in</p>Formula:C17H11N3O6SPurezza:97.74%Colore e forma:SolidPeso molecolare:385.35NPS ALX Compound 4a
CAS:NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Formula:C25H25N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:431.55Benorilate
CAS:Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.Formula:C17H15NO5Purezza:98.39% - 99.85%Colore e forma:SolidPeso molecolare:313.3Vortioxetine
CAS:Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.Formula:C18H22N2SPurezza:99.34% - 99.34%Colore e forma:SolidPeso molecolare:298.45Decloxizine dihydrochloride
CAS:<p>Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist.</p>Formula:C21H28N2O2·2ClHPurezza:99.73%Colore e forma:SolidPeso molecolare:413.39Lodoxamide
CAS:<p>Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.</p>Formula:C11H6ClN3O6Purezza:99.13% - 99.81%Colore e forma:SolidPeso molecolare:311.63Atipamezole hydrochloride
CAS:<p>Atipamezole is a synthetic α2 adrenergic receptor antagonist.</p>Formula:C14H16N2·HClPurezza:99.74%Colore e forma:SolidPeso molecolare:248.75Irdabisant hydrochloride
CAS:<p>Irdabisant (CEP-26401) is a selective H3R inverse agonist, BBB-penetrable, with cognition-enhancing effects.</p>Formula:C18H24ClN3O2Colore e forma:SolidPeso molecolare:349.86Bevantolol
CAS:Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].Formula:C20H27NO4Colore e forma:SolidPeso molecolare:345.43SB-200646
CAS:SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptorFormula:C15H14N4OPurezza:99.61%Colore e forma:SolidPeso molecolare:266.35-HT1A modulator 2 hydrochloride
CAS:5-HT1A modulator 2 hydrochloride is a modulator of 5-HT1A showing an affinity of 53 nM for 5-HT1A binding.Formula:C11H16ClNOPurezza:98.5%Colore e forma:SolidPeso molecolare:213.7Picotamide
CAS:<p>Picotamide has anticoagulant and fibrinolytic properties.</p>Formula:C21H20N4O3Purezza:98.90%Colore e forma:SolidPeso molecolare:376.41Batefenterol Succinate
CAS:Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.Formula:C44H48ClN5O11Colore e forma:SolidPeso molecolare:858.34Fenspiride
CAS:<p>Fenspiride: oral non-steroidal anti-inflammatory, treats respiratory infections/otitis, inhibits H1-histamine receptors and PDE 3, 4, 5.</p>Formula:C15H20N2O2Colore e forma:SolidPeso molecolare:260.33CRT0273750
CAS:CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.Formula:C25H22ClF3N4O2Purezza:99.91%Colore e forma:SolidPeso molecolare:502.92Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Colore e forma:SolidPeso molecolare:533.63Rimcazole
CAS:Rimcazole is a sigma receptor antagonist. It also binds to the dopamine transporter and inhibiting dopamine uptake.Formula:C21H27N3Purezza:98%Colore e forma:SolidPeso molecolare:321.46A-582941 dihydrochloride
CAS:<p>A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial</p>Formula:C17H22Cl2N4Purezza:99.55%Colore e forma:SolidPeso molecolare:353.29Tesmilifene fumarate
CAS:Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。Formula:C23H29NO5Purezza:99.86%Colore e forma:SolidPeso molecolare:399.48DSP 4
CAS:DSP 4: neurotoxin targeting locus coeruleus, crosses blood-brain barrier, forms aziridinium, enters nerves via noradrenaline transporter.Formula:C11H15BrClNColore e forma:SolidPeso molecolare:276.6Milveterol
CAS:Milveterol is a long-acting β(2)-adrenoceptor agonist.Formula:C25H29N3O4Colore e forma:SolidPeso molecolare:435.52Zacopride
CAS:Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias.Formula:C15H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:309.79BAY 41-2272
CAS:<p>BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.</p>Formula:C20H17FN6Purezza:99.54%Colore e forma:SolidPeso molecolare:360.39
