Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Formula:C20H24N2OSColore e forma:SolidPeso molecolare:340.48PF-06882961 Tris
CAS:<p>PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>Formula:C35H41FN6O7Purezza:98.74% - 99.79%Colore e forma:SolidPeso molecolare:676.7CPI-444
CAS:<p>CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.</p>Formula:C20H21N7O3Purezza:98.78%Colore e forma:SolidPeso molecolare:407.43Dimemorfan phosphate
CAS:<p>Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.</p>Formula:C18H25N·H3O4PPurezza:99.65%Colore e forma:SolidPeso molecolare:353.4Neuropeptide SF(mouse,rat) acetate
<p>Neuropeptide SF (mouse,rat) acetate is a NPFF receptor agonist with Ki of 48.4 nM (NPFF1) & 12.1 nM (NPFF2), enhancing ASIC3 current.</p>Formula:C42H69N13O12Purezza:98.37%Colore e forma:SolidPeso molecolare:948.08Neuropeptide EI, rat acetate
<p>Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.</p>Formula:C65H102N16O25Purezza:95.55%Colore e forma:SolidPeso molecolare:1507.6NIBR189
CAS:<p>NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)</p>Formula:C21H21BrN2O3Purezza:97%Colore e forma:ColourlessPeso molecolare:429.31Methiothepin mesylate
CAS:<p>Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.</p>Formula:C21H28N2O3S3Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:452.65Vortioxetine
CAS:<p>Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.</p>Formula:C18H22N2SPurezza:99.34% - 99.34%Colore e forma:SolidPeso molecolare:298.45Atipamezole hydrochloride
CAS:<p>Atipamezole is a synthetic α2 adrenergic receptor antagonist.</p>Formula:C14H16N2·HClPurezza:99.74%Colore e forma:SolidPeso molecolare:248.75Ipragliflozin
CAS:<p>Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.</p>Formula:C21H21FO5SPurezza:99.38% - 99.70%Colore e forma:SolidPeso molecolare:404.45Idalopirdine Hydrochloride
CAS:<p>Idalopirdine Hydrochloride (Lu AE58054 Hydrochloride) is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.</p>Formula:C20H20ClF5N2OPurezza:99.77%Colore e forma:SolidPeso molecolare:434.83Risperidone hydrochloride
CAS:<p>Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).</p>Formula:C23H28ClFN4O2Colore e forma:SolidPeso molecolare:446.95R 396 acetate
<p>R 396 acetate is an NK-2 Tachykinin Receptor <br>Antagonist.</p>Formula:C41H55N9O12Purezza:99.52%Colore e forma:SolidPeso molecolare:865.93Fexofenadine
CAS:<p>Fexofenadine, a non-sedating antihistamine, treats allergies like hay fever and urticaria.</p>Formula:C32H39NO4Purezza:99.35%Colore e forma:White To Off-White SolidPeso molecolare:501.66[Lys8, Lys9]-Neurotensin (8-13) acetate
<p>[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2</p>Formula:C40H68N8O10Purezza:99.31%Colore e forma:SolidPeso molecolare:821.02Mebhydrolin
CAS:<p>Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist.</p>Formula:C19H20N2Purezza:99.3% - ≥98%Colore e forma:SolidPeso molecolare:276.38SB-203186 hydrochloride
CAS:<p>SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist</p>Formula:C16H20N2O2·HClPurezza:99.64%Colore e forma:SolidPeso molecolare:308.81Zotepine
CAS:<p>Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,</p>Formula:C18H18ClNOSPurezza:99.78%Colore e forma:SolidPeso molecolare:331.86Cinaciguat hydrochloride
CAS:<p>Cinaciguat( BAY582667, BAY58-2667) is a soluble guanosine cyclase activator that can prevent cardiac dysfunction in rat models of type 1 diabetes.</p>Formula:C36H40ClNO5Colore e forma:SolidPeso molecolare:602.17Exo-1
CAS:<p>Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, as</p>Formula:C15H12FNO3Purezza:99.45%Colore e forma:SolidPeso molecolare:273.26CAY10526
CAS:<p>CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.</p>Formula:C12H7BrO3SPurezza:98.75%Colore e forma:SolidPeso molecolare:311.15Olodaterol hydrochloride
CAS:<p>Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist that exerts its pharmacological effect by binding and activating β2-AR.</p>Formula:C21H27ClN2O5Purezza:99.11%Colore e forma:SolidPeso molecolare:422.9Vortioxetine hydrobromide
CAS:<p>Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33</p>Formula:C18H22N2S·HBrPurezza:98.85% - 99.98%Colore e forma:SolidPeso molecolare:379.36ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purezza:99.12%Colore e forma:SolidPeso molecolare:307.1395-Iodotubercidin
CAS:<p>5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM.</p>Formula:C11H13IN4O4Purezza:99.98%Colore e forma:Tan SolidPeso molecolare:392.15Syk Inhibitor II dihydrochloride dihydrate
CAS:<p>Potent, selective ATP-competitive Syk Inhibitor II (IC50: 41 nM), with anti-allergic properties, in dihydrochloride dihydrate form.</p>Formula:C14H21Cl2F3N6O3Colore e forma:SolidPeso molecolare:449.26Ajmalicine hydrochloride
CAS:<p>Ajmalicine hydrochloride is a potent α1-adrenoceptor blocker, non-competitive nicotine receptor inhibitor, anti-hypertensive, and sedative. IC50: 72.3 μM.</p>Formula:C21H25ClN2O3Colore e forma:SolidPeso molecolare:388.89Zacopride hydrochloride
CAS:<p>Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.</p>Formula:C15H20ClN3O2·HClPurezza:98.32%Colore e forma:SolidPeso molecolare:346.26Bosentan
CAS:<p>Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.</p>Formula:C27H29N5O6SPurezza:99.74% - 99.84%Colore e forma:Pale Yellow To Off-White SolidPeso molecolare:551.614PRX-08066
CAS:<p>PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.</p>Formula:C19H17ClFN5SPurezza:97.79% - 98.07%Colore e forma:SolidPeso molecolare:401.89BisfluoroModafinil
CAS:<p>CRL-40940 is a selective dopaminergic reuptake inhibitor</p>Formula:C15H13F2NO2SPurezza:99.19%Colore e forma:SolidPeso molecolare:309.33Naftopidil dihydrochloride
CAS:<p>Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.</p>Formula:C24H28N2O3·2HClPurezza:99.76%Colore e forma:White SolidPeso molecolare:465.41Neuropeptide S (Rat) acetate
<p>Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor.</p>Formula:C97H164N34O29Purezza:95.36%Colore e forma:SolidPeso molecolare:2270.59α-MSH
CAS:<p>α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.</p>Formula:C77H109N21O19SPurezza:99.10% - 99.67%Colore e forma:White PowderPeso molecolare:1664.89BRL-15572 dihydrochloride
CAS:<p>BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.</p>Formula:C25H27ClN2O·2HClPurezza:99.74%Colore e forma:SolidPeso molecolare:479.87RS-127445 hydrochloride
CAS:<p>RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).</p>Formula:C17H17ClFN3Purezza:99.48%Colore e forma:SolidPeso molecolare:317.79GSK 789472 hydrochloride
CAS:<p>GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.</p>Formula:C15H22ClN3OPurezza:99.89%Colore e forma:SolidPeso molecolare:295.81Nifenalol
CAS:<p>Nifenalol is an adrenergic beta-blocker with good antiarrhythmic properties. It tends to lower blood pressure and provide protection against angina.</p>Formula:C11H16N2O3Purezza:98%Colore e forma:SolidPeso molecolare:224.26DOPEXAMINE
CAS:<p>Dopexamine is a dopaminergic agonist</p>Formula:C22H32N2O2Purezza:99.42%Colore e forma:SolidPeso molecolare:356.5GR-73632
CAS:<p>Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).</p>Formula:C40H59N7O6SPurezza:99.68%Colore e forma:SolidPeso molecolare:766Tianeptine
CAS:<p>Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H25ClN2O4SPurezza:99.04%Colore e forma:SolidPeso molecolare:436.95Bunazosin
CAS:<p>Bunazosin is a potent and selective α1-adrenoceptor antagonist that can be used for antihypertensive and ocular hypotensive research [1].</p>Formula:C19H27N5O3Colore e forma:SolidPeso molecolare:373.45TG4-155
CAS:<p>TG4-155: brain-penetrant EP2 inhibitor, KB 2.4 nM; >1000x weaker at EP4, KB 11.4 μM; selective over other receptors/channels.</p>Formula:C23H26N2O4Purezza:97.2%Colore e forma:SolidPeso molecolare:394.46Histrelin acetate
CAS:<p>Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency.</p>Formula:C68H90N18O14Purezza:99.92%Colore e forma:SolidPeso molecolare:1383.55Cotadutide acetate
<p>Cotadutide acetate is a potent GLP-1 and glucagon receptor dual agonist with EC50s of 6.9 pM and 10.2 pM.</p>Formula:C169H256N42O57Purezza:98.28%Colore e forma:SolidPeso molecolare:3788.14[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
<p>Broad-spectrum neuropeptide inverse agonist/antagonist; potent at ghrelin receptor (EC50 = 5.2 nM); inhibits cancer growth, induces apoptosis.</p>Formula:C81H113N19O14Purezza:97.68%Colore e forma:SolidPeso molecolare:1576.91Brompheniramine
CAS:<p>Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.</p>Formula:C16H19BrN2Colore e forma:SolidPeso molecolare:319.24R715 TFA(185052-09-9 free base)
<p>R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49).</p>Formula:C59H82F3N13O14Purezza:>99.99%Colore e forma:SolidPeso molecolare:1254.36Metoclopramide
CAS:<p>Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.</p>Formula:C14H22ClN3O2Purezza:99.75%Colore e forma:SolidPeso molecolare:299.80
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