OICR41114
Ref. TM-T203318
10mg
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50mg
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Product Information
Name:OICR41114
Brand:Targetmol
Description:OICR41114 (PROTAC4) is a PROTAC degrader targeting WDR5. It effectively degrades endogenous WDR5 with an EC50 of 40 nM and a Dmax of 49%. The degradation of HiBiT-tagged WDR5 by OICR41114 occurs in a proteasome-dependent manner. This compound is composed of a target protein ligand, Dimethyl-F-OICR-9429-COOH, an E3 ligase ligand, OICR-8268-acrylic acid, and a PROTAC linker, Amino-PEG9-amine. Notably, the conjugate of the E3 ligase ligand and the linker is OICR-8268-acrylic acid-amino-PEG9-amine.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1475.36
Formula:C70H83Cl2F6N9O15
Color/Form:Solid
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