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JAK1/STAT3-IN-1

Ref. TM-T205385

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Targetmol

Product Information

Name:JAK1/STAT3-IN-1
Brand:Targetmol
Description:JAK1/STAT3-IN-1 (compound 4f) functions as an anti-atopic dermatitis (AD) agent by inhibiting the JAK1/STAT3 signaling pathway. It has an IC50 value of 2.17 μM for inhibiting NO production. Additionally, JAK1/STAT3-IN-1 improves skin conditions in AD-like mice by reducing inflammatory infiltration, suppressing the expression of p-JAK1/JAK1 and p-STAT3/STAT3, and alleviating the hyperimmune response induced by MC903 (Calcipotriol).
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:548.67
Formula:C30H33FN4O3S
Color/Form:Solid

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