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GSK3β-IN-2

CAS:

Ref. TM-T205461

GSK3β-IN-2
Targetmol

Product Information

Name:GSK3β-IN-2
Brand:Targetmol
Description:GSK3β-IN-2 (Compound S01) is an inhibitor of GSK3β with an IC50 of 0.35 nM. It activates the Wnt/β-catenin signaling pathway, promoting neurogenesis and neurite outgrowth. GSK3β-IN-2 reduces tau protein phosphorylation induced by Aβ at the Ser396 site, thereby decreasing neurofibrillary tangles. Furthermore, GSK3β-IN-2 improves Alzheimer's disease symptoms in a zebrafish model.
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Chemical properties

Molecular weight:390.437
Formula:C25H18N4O
Color/Form:Solid

Technical inquiry about: GSK3β-IN-2

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