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PROTAC JAK2 degrader-1

Ref. TM-T210842

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Targetmol

Product Information

Name:PROTAC JAK2 degrader-1
Brand:Targetmol
Description:PROTAC JAK2 degrader-1 (Compound 10i) is a JAK2 PROTAC degrader with a DC50 of 27.35 nM against JAK2V617F. It facilitates the ubiquitination and degradation of JAK2. This compound also inhibits the phosphorylation of JAK2, STAT3, and STAT5, and is applicable in the study of myeloproliferative neoplasms.
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Chemical properties

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