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Pyridone 6
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Pyridone 6

CAS: 457081-03-7

Ref. TM-T3080

1mg
81.00 €
2mg
105.00 €
5mg
159.00 €
10mg
218.00 €
25mg
441.00 €
50mg
648.00 €
100mg
918.00 €
500mg
1,838.00 €
1mL*10mM (DMSO)
176.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024

Product Information

Name:
Pyridone 6
Synonyms:
  • Janus-Associated Kinase Inhibitor I
  • JAK Inhibitor I
  • JAK Inhibitor
  • CMP 6
  • (3E)-4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol
  • Merck-5
  • Merk-5
  • Jak Inhibitor I
  • Cmp 6
  • 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[H]imidazo[4,5-F]isoquinolin-7-one
  • See more synonyms
  • Jak inhibitor I (merck 5)
  • 2-tert-butyl-9-fluoro-3H-benzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one
Description:

Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
309.34
Formula:
C18H16FN3O
Purity:
97.10% - 98.74%
Color/Form:
Solid
InChI:
InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
InChI key:
InChIKey=VNDWQCSOSCCWIP-UHFFFAOYSA-N
SMILES:
CC(C)(C)c1nc2c3cc[nH]c(=O)c3c3cc(F)ccc3c2[nH]1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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