WHI-P97
CAS: 211555-05-4
Ref. TM-T4657
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 586.00 € | ||
| 500mg | 1,253.00 € | ||
| 1ml*10 (DMSO) | 103.00 € |
Product Information
- WHI-P-97
WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane and consequently 5-LO-dependent leukotriene (LT) synthesis after IgE receptor/FcepsilonRI crosslinking by >90% at low micromolar concentrations. WHI-P97 did not directly inhibit the enzymatic activity of 5-LO, but prevented its translocation to the nuclear membrane without affecting the requisite calcium signal.
Chemical properties
Technical inquiry about: TM-T4657 WHI-P97
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