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Protosappanin A

CAS: 102036-28-2

Ref. TM-TJS1779

1mg
143.00 €
5mg
423.00 €
10mg
624.00 €
25mg
984.00 €
50mg
1,327.00 €
100mg
1,782.00 €
1ml*10 (DMSO)
366.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Protosappanin A
Synonyms:
  • PTA
  • 3,10,11-Trihydroxy-6H-dibenz[b,d]oxocin-7(8H)-one
  • 3,10,11-trihydroxy-6H-dibenzo[b,d]oxocin-7(8H)-one
  • 6H-Dibenz(b,d)oxocin-7(8H)-one, 3,10,11-trihydroxy-
  • Sappanol B
Description:

Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
272.25
Formula:
C15H12O5
Purity:
100%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-TJS1779 Protosappanin A

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