Angiogénese
Os inibidores da angiogênese são compostos que interferem na formação de novos vasos sanguíneos, um processo crítico no crescimento e metástase do câncer. Ao inibir a angiogênese, esses compostos podem restringir o suprimento de sangue para os tumores, retardando ou interrompendo seu crescimento. Os inibidores da angiogênese são essenciais na pesquisa do câncer e no desenvolvimento terapêutico, fornecendo insights sobre os mecanismos de progressão tumoral e oferecendo potenciais tratamentos para o câncer e outras doenças relacionadas à angiogênese. Na CymitQuimica, oferecemos uma ampla gama de inibidores da angiogênese de alta qualidade para apoiar sua pesquisa em oncologia e biologia vascular.
Subcategorias de "Angiogénese"
- BTK(147 produtos)
- Bcr-Abl(103 produtos)
- EGFR(572 produtos)
- FAK(71 produtos)
- FLT(91 produtos)
- Receptor do Factor de Crescimento Fibroblasto (FGFR)(169 produtos)
- JAK(246 produtos)
- PDGFR(126 produtos)
- RAAS(88 produtos)
- Src(80 produtos)
- Syk(37 produtos)
- Trombina(47 produtos)
- VDA(2 produtos)
- VEGFR(267 produtos)
Exibir 6 mais subcategorias
Foram encontrados 1483 produtos de "Angiogénese"
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Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:487.53GluR6 antagonist-1
CAS:<p>GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.</p>Fórmula:C15H11ClN2OSPureza:99.89%Cor e Forma:SolidPeso molecular:302.78Cetuximab
CAS:<p>Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).</p>Fórmula:C107H179N35O36S7Pureza:95 - 98.60%Cor e Forma:LiquidPeso molecular:152 kDaBisindolylmaleimide I
CAS:<p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>Fórmula:C25H24N4O2Pureza:98.19% - 98.75%Cor e Forma:Orange SolidPeso molecular:412.48A 83-01 sodium salt
CAS:A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.Fórmula:C25H19N5NaSCor e Forma:SolidPeso molecular:444.51NCGC00262650
CAS:<p>NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.</p>Fórmula:C18H20N4OPureza:98%Cor e Forma:SolidPeso molecular:308.38Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Fórmula:C20H20N2OPureza:98.17% - 99.754%Cor e Forma:SolidPeso molecular:304.39Tranilast
CAS:<p>Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of</p>Fórmula:C18H17NO5Pureza:99.67% - >99.99%Cor e Forma:White With Light Yellow Crystalline PowderPeso molecular:327.33Takeda-6d
CAS:<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Fórmula:C27H19ClFN5O3SPureza:98.27%Cor e Forma:SolidPeso molecular:547.99Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Fórmula:C23H26FN5O3Pureza:97.35%Cor e Forma:SolidPeso molecular:439.48Regorafenib mesylate
CAS:<p>Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.</p>Fórmula:C22H19ClF4N4O6SCor e Forma:SolidPeso molecular:578.92Syk Inhibitor II dihydrochloride
CAS:<p>Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.</p>Fórmula:C14H17Cl2F3N6OPureza:98.53%Cor e Forma:SolidPeso molecular:413.22Vandetanib hydrochloride
CAS:<p>Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).</p>Fórmula:C22H25BrClFN4O2Cor e Forma:SolidPeso molecular:511.81BMS817378
CAS:<p>BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).</p>Fórmula:C24H18ClF2N4O7PPureza:>99.99%Cor e Forma:SolidPeso molecular:578.85Gefitinib dihydrochloride
CAS:<p>Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.</p>Fórmula:C22H26Cl3FN4O3Cor e Forma:SolidPeso molecular:519.82SPHINX31
CAS:<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Fórmula:C27H24F3N5O2Pureza:98.81% - 99.3%Cor e Forma:SolidPeso molecular:507.51Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C19H32N2O4Pureza:99.26%Cor e Forma:CoaPeso molecular:352.471-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Fórmula:C19H19N5Pureza:99.85%Cor e Forma:White Cyrstalline SolidPeso molecular:317.39Benidipine hydrochloride
CAS:<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Fórmula:C28H32ClN3O6Pureza:99.80%Cor e Forma:SolidPeso molecular:542.03Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:500.83AZD3759 hydrochloride
CAS:<p>AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.</p>Fórmula:C22H24Cl2FN5O3Pureza:99.62%Cor e Forma:SolidPeso molecular:496.36CEP-28122 mesylate salt
<p>CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.</p>Fórmula:C29H39ClN6O6SCor e Forma:SolidPeso molecular:635.17JK-P3
CAS:<p>JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.</p>Fórmula:C18H17N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:323.35KX2-361
CAS:<p>KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma</p>Fórmula:C24H24FN3O2Pureza:99.64% - 99.68%Cor e Forma:SolidPeso molecular:405.46Blu-782
CAS:<p>Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)</p>Fórmula:C31H42N6O4Pureza:99.51%Cor e Forma:SolidPeso molecular:562.7Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Fórmula:C21H23N5O3SPureza:98.03% - ≥95%Cor e Forma:SolidPeso molecular:425.5Gusacitinib HCl
CAS:<p>Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.</p>Fórmula:C24H29ClN8O2Cor e Forma:SolidPeso molecular:497HG-14-10-04
CAS:<p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>Fórmula:C29H34ClN7OPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:532.08Brigatinib
CAS:<p>Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.</p>Fórmula:C29H39ClN7O2PPureza:97.18% - >99.99%Cor e Forma:SolidPeso molecular:584.09DGY-06-116
CAS:<p>DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.</p>Fórmula:C32H33ClN8O2Pureza:97.65%Cor e Forma:SolidPeso molecular:597.11Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Fórmula:C21H21FN6OPureza:99.35% - 99.92%Cor e Forma:SolidPeso molecular:392.43Acriflavine Hydrochloride
CAS:Acriflavine HCl is a HIF-1α inhibitor reducing PGK1, VEGF, and HIF-1α levels both in vitro and in vivo.Fórmula:C14H14ClN3Pureza:99.8%Cor e Forma:SolidPeso molecular:259.73VEGFR2-IN-2
CAS:<p>VEGFR2-IN-2 has anti-inflammatory and analgesic activities.</p>Fórmula:C15H11BrN2OPureza:99.504%Cor e Forma:SolidPeso molecular:315.16Tesevatinib
CAS:<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Cor e Forma:SolidPeso molecular:491.39Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Fórmula:C13H9FN2SPureza:98.01%Cor e Forma:SolidPeso molecular:244.29Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Cor e Forma:SolidPeso molecular:530.5CA-4948
CAS:<p>CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.</p>Fórmula:C24H25N7O5Pureza:99.35% - 99.88%Cor e Forma:SolidPeso molecular:491.5Tivozanib
CAS:<p>Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.</p>Fórmula:C22H19ClN4O5Pureza:98.08% - 99.67%Cor e Forma:SolidPeso molecular:454.86Tropisetron
CAS:Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Fórmula:C17H20N2O2Pureza:99.68%Cor e Forma:White SolidPeso molecular:284.35Quizartinib HCl
CAS:<p>Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.</p>Fórmula:C29H34Cl2N6O4SCor e Forma:SolidPeso molecular:633.59(S)-Afatinib
CAS:<p>(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.</p>Fórmula:C24H25ClFN5O3Pureza:99.22% - >99.99%Cor e Forma:Off-White SolidPeso molecular:485.942-(1,8-naphthyridin-2-yl)phenol
CAS:<p>2-NP is a STAT1 enhancer.</p>Fórmula:C14H10N2OPureza:99.33% - 99.82%Cor e Forma:SolidPeso molecular:222.24Nastorazepide
CAS:<p>Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.</p>Fórmula:C29H36N4O5Pureza:99.83%Cor e Forma:SolidPeso molecular:520.622,4-DPD
CAS:<p>2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)</p>Fórmula:C11H13NO4Pureza:99.74%Cor e Forma:Yellow Solid CrystallinePeso molecular:223.23MELK-8a
CAS:<p>MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).</p>Fórmula:C25H32N6OCor e Forma:SolidPeso molecular:432.56PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Fórmula:C26H35Cl2N7OPureza:99.92%Cor e Forma:SolidPeso molecular:532.514SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Fórmula:C33H38N8O4SPureza:96.4% - 99.67%Cor e Forma:SolidPeso molecular:642.777BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Fórmula:C16H10BrN3O2Pureza:99.67%Cor e Forma:SolidPeso molecular:356.175-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:<p>5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.</p>Fórmula:C12H9N3SPureza:97%Cor e Forma:SolidPeso molecular:227.29
![5-phenylthieno[2,3-d]pyrimidin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT50042.webp&w=3840&q=75)