Angiogénese
Os inibidores da angiogênese são compostos que interferem na formação de novos vasos sanguíneos, um processo crítico no crescimento e metástase do câncer. Ao inibir a angiogênese, esses compostos podem restringir o suprimento de sangue para os tumores, retardando ou interrompendo seu crescimento. Os inibidores da angiogênese são essenciais na pesquisa do câncer e no desenvolvimento terapêutico, fornecendo insights sobre os mecanismos de progressão tumoral e oferecendo potenciais tratamentos para o câncer e outras doenças relacionadas à angiogênese. Na CymitQuimica, oferecemos uma ampla gama de inibidores da angiogênese de alta qualidade para apoiar sua pesquisa em oncologia e biologia vascular.
Subcategorias de "Angiogénese"
- BTK(165 produtos)
- Bcr-Abl(117 produtos)
- EGFR(562 produtos)
- FAK(72 produtos)
- FLT(89 produtos)
- Receptor do Factor de Crescimento Fibroblasto (FGFR)(177 produtos)
- JAK(245 produtos)
- PDGFR(127 produtos)
- RAAS(86 produtos)
- Src(82 produtos)
- Syk(37 produtos)
- Trombina(52 produtos)
- VDA(2 produtos)
- VEGFR(239 produtos)
Exibir 6 mais subcategorias
Foram encontrados 2243 produtos de "Angiogénese"
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CZY43
CZY43 is an HER3 degrader that effectively induces degradation of HER3 in breast cancer SKBR3 cells in a dose- and time-dependent manner. It efficiently inhibits HER3-dependent signaling and cancer cell growth, outperforming Bosutinib.Fórmula:C42H53Cl2N5O3Cor e Forma:SolidPeso molecular:746.808Bevasiranib sodium
CAS:Bevasiranib sodium, a siRNA, silences genes for VEGF, key in CNV pathogenesis and wet AMD precursor.Cor e Forma:SolidDSPE-PEG5000-GE11
DSPE-PEG5000-GE11 is a PEG compound composed of DSPE and the EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells with EGFR overexpression. DSPE-PEG5000-GE11 is utilized in drug delivery.Cor e Forma:Odour SolidhCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Fórmula:C24H28N6O6SPureza:98%Cor e Forma:SolidPeso molecular:528.58Tephrosin
CAS:Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.Fórmula:C23H22O7Pureza:98%Cor e Forma:SolidPeso molecular:410.42Simotinib hydrochloride
CAS:Simotinib hydrochloride: selective oral EGFR inhibitor, IC50 19.9 nM, potent anticancer agent.Fórmula:C25H27Cl2FN4O4Cor e Forma:SolidPeso molecular:537.41EGFR-IN-43
EGFR-IN-43 (17c) is a potent EGFR inhibitor with ER antagonist action, tamoxifen/endoxifen+gefitinib linkage, and strong anticancer activity.Fórmula:C50H55ClFN5O5Cor e Forma:SolidPeso molecular:860.45DP-C-4
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].Cor e Forma:LiquidSecretin, canine
CAS:Secretin: endocrine hormone, increases bicarbonate-rich pancreatic fluid, regulates canine gastric functions via Src kinase pathway.Fórmula:C131H222N44O41Pureza:98%Cor e Forma:SolidPeso molecular:3069.43Suvemcitug
CAS:Suvemcitug, an IgG1κ antibody, specifically targets vascular endothelial growth factor (VEGF) and is derived from the African hare (Oryctolagus cuniculus) [1].Pureza:98%Cor e Forma:LiquidLCK degrader-2
LCKdegrader-2 (Compound 17) is a Lck molecular glue degrader. It is applicable for research in cancers such as acute lymphoblastic leukemia (ALL).Cor e Forma:Odour SolidTyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
CAS:Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.Fórmula:C88H138N20O34P2Pureza:98%Cor e Forma:SolidPeso molecular:2082.1SOS1/EGFR-IN-2
SOS1/EGFR-IN-2 (Compound 4) functions as a dual inhibitor of SOS1 and EGFR, exhibiting IC50 values of 8.3 and 14.6 nM, respectively. It demonstrates significant antiproliferative effects on cancer cells harboring various KRAS mutations.Fórmula:C25H29F3N4O3Cor e Forma:SolidPeso molecular:490.52Bemarituzumab
CAS:Bemarituzumab: humanized IgG1 antibody inhibits FGFR2b, may be used in cancer research.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:144 kDaLewis y tetrasaccharide
CAS:Lewis Y tetrasaccharide, a derivative of Lewis X, is an antigen linked to ovarian cancer metastasis and bad prognosis.Fórmula:C26H45NO19Cor e Forma:SolidPeso molecular:675.63TL13-112
CAS:TL13-112 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.14 nM).Fórmula:C49H60ClN9O10SPureza:98%Cor e Forma:SolidPeso molecular:1002.57Modotuximab
CAS:Modotuximab (DS 1024) is a humanized antibody targeting EGFR with antitumor activity that accelerates the internalization and degradation of EGFR.Pureza:95.5% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 99.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.45 kDaNezutatug
CAS:Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].Pureza:98%Cor e Forma:LiquidMulti-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.Fórmula:C21H20ClFN2OSPureza:98%Cor e Forma:SolidPeso molecular:402.91VEGFR2/HDAC1-IN-1
VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC.Pureza:98%Cor e Forma:Odour Solid
