Angiogénese

Os inibidores da angiogênese são compostos que interferem na formação de novos vasos sanguíneos, um processo crítico no crescimento e metástase do câncer. Ao inibir a angiogênese, esses compostos podem restringir o suprimento de sangue para os tumores, retardando ou interrompendo seu crescimento. Os inibidores da angiogênese são essenciais na pesquisa do câncer e no desenvolvimento terapêutico, fornecendo insights sobre os mecanismos de progressão tumoral e oferecendo potenciais tratamentos para o câncer e outras doenças relacionadas à angiogênese. Na CymitQuimica, oferecemos uma ampla gama de inibidores da angiogênese de alta qualidade para apoiar sua pesquisa em oncologia e biologia vascular.

Subcategorias de "Angiogénese"

Exibir 6 mais subcategorias

Foram encontrados 1884 produtos de "Angiogénese"

Pureza (%)

100

produtos por página.

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PF-06672131
CAS:
- 1621002-27-4
PF-06672131 is a selective EGFR kinase inhibitor.
Fórmula:C₂₃H₂₁ClFN₅O₂
Cor e Forma:Solid
Peso molecular:453.9
Ref: TM-T70369
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Lanraplenib monosuccinate
CAS:
- 1800046-97-2
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
Fórmula:C₂₇H₃₁N₉O₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:561.59
Ref: TM-T11824L
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BTK-IN-24
CAS:
- 1370466-81-1
BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.
Fórmula:C₂₆H₁₉F₄N₅O₂
Pureza:99.61%
Cor e Forma:Solid
Peso molecular:509.46
Ref: TM-T14937
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TK4b
CAS:
- 2232890-81-0
TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).
Fórmula:C₂₁H₂₂N₂O₂
Cor e Forma:Solid
Peso molecular:334.41
Ref: TM-T61020
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TX-1918
CAS:
- 503473-32-3
<p>TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.</p>
Fórmula:C₁₄H₁₂O₃
Cor e Forma:Solid
Peso molecular:228.24
Ref: TM-T71815
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NAMI-A
CAS:
- 201653-76-1
NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.
Fórmula:C₈H₁₅Cl₄N₄ORuS
Pureza:98%
Cor e Forma:Solid
Peso molecular:458.18
Ref: TM-T16266
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Sovleplenib
CAS:
- 1415792-84-5
Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.
Fórmula:C₂₄H₃₀N₆O₃S
Pureza:99.71%
Cor e Forma:Solid
Peso molecular:482.6
Ref: TM-T32088
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ALK5-IN-26
CAS:
- 2785430-82-0
ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).
Fórmula:C₂₄H₂₅FN₈
Cor e Forma:Solid
Peso molecular:444.51
Ref: TM-T62613
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Cenisertib benzoate
CAS:
- 1145859-64-8
Cenisertib benzoate is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity.
Fórmula:C₃₁H₃₆FN₇O₃
Cor e Forma:Solid
Peso molecular:573.66
Ref: TM-T71384
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DMH4
CAS:
- 515880-75-8
DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.
Fórmula:C₂₄H₂₄N₄O₂
Pureza:99.58%
Cor e Forma:Solid
Peso molecular:400.47
Ref: TM-T22737
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EGFR-IN-73
CAS:
- 2857033-34-0
EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, exhibiting an IC50 value of 119 nM [1].
Fórmula:C₁₉H₁₇ClFN₃O₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:405.81
Ref: TM-T73165
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ER-27319
CAS:
- 201010-95-9
ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine
Fórmula:C₂₀H₂₂N₂O₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:370.4
Ref: TM-T78641
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A-420983
CAS:
- 330789-03-2
A-420983 is a novel potent Lck inhibitor, exhibiting oral efficacy in animal models of delayed-type hypersensitivity and organ transplant rejection.
Fórmula:C₃₃H₃₉N₉O₂
Cor e Forma:Solid
Peso molecular:593.72
Ref: TM-T69431
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JAK-IN-20
CAS:
- 1654776-91-6
JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.
Fórmula:C₂₈H₃₀FN₇O₂
Cor e Forma:Solid
Peso molecular:515.58
Ref: TM-T63581
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Peficitinib hydrochloride
CAS:
- 1353219-06-3
Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).
Fórmula:C₁₈H₂₃ClN₄O₂
Cor e Forma:Solid
Peso molecular:362.86
Ref: TM-T61365
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NSC114126
CAS:
- 24909-18-0
<p>NSC114126 is a potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.</p>
Fórmula:C₂₂H₂₀O₄
Cor e Forma:Solid
Peso molecular:348.39
Ref: TM-T61177
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RG 14921
CAS:
- 144909-21-7
RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.
Fórmula:C₁₁H₉NO₃
Cor e Forma:Solid
Peso molecular:203.19
Ref: TM-T34310
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Mutated EGFR-IN-3
CAS:
- 2375107-27-8
Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.
Fórmula:C₃₁H₂₉FN₄O₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:508.59
Ref: TM-T12131
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PF-719 free base
CAS:
- 1404454-02-9
PF-719 is a potent, selective Pyk2 inhibitor with IC50 of 17 nM.
Fórmula:C₂₂H₂₇F₃N₆O
Cor e Forma:Solid
Peso molecular:448.48
Ref: TM-T70751
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Thi-DPPY
CAS:
- 2307699-34-7
Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.
Fórmula:C₂₈H₂₈ClN₅O₄S
Cor e Forma:Solid
Peso molecular:566.07
Ref: TM-T64008