Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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2',5'-Dimethoxyacetophenone
CAS:Produto ControladoFórmula:C10H12O3Cor e Forma:NeatPeso molecular:180.24-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid
CAS:Produto Controlado<p>Applications Intermediate in the production of cell death regulators and apoptosis promoters.<br>References Park, C., et al.: J. Med. Chem., 51, 6902 (2008),<br></p>Fórmula:C26H31ClN2O2Cor e Forma:NeatPeso molecular:438.99Apogossypolone
CAS:Produto Controlado<p>Applications Apogossypolone is an anticancer agent that induces apoptosis in carcinoma cells. Antiproliferative.<br>References Zubair, H. et al.: Eur J. Pharm. Sci., 47, 280 (2012);<br></p>Fórmula:C28H26O8Cor e Forma:NeatPeso molecular:490.50Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Fórmula:C22H14Pureza:99.97%Cor e Forma:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Peso molecular:278.35SAR405838
CAS:<p>MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.</p>Fórmula:C29H34Cl2FN3O3Pureza:98.63%Cor e Forma:SolidPeso molecular:562.5NPB
CAS:<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Fórmula:C29H31Cl2N3O2Pureza:99.93%Cor e Forma:SolidPeso molecular:524.48Riviciclib hydrochloride
CAS:<p>Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.</p>Fórmula:C21H20ClNO5·HClPureza:99.51%Cor e Forma:SolidPeso molecular:438.3SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Cor e Forma:Orange PowderPeso molecular:568.09Cot inhibitor-2
CAS:<p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>Fórmula:C26H25Cl2FN8Pureza:98.87%Cor e Forma:SolidPeso molecular:539.43Flurochloridone
CAS:<p>Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.</p>Fórmula:C12H10Cl2F3NOPureza:99.86%Cor e Forma:SolidPeso molecular:312.12L-Cystathionine
CAS:<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Fórmula:C7H14N2O4SPureza:96.43% - >99.99%Cor e Forma:SolidPeso molecular:222.26Camptothecin
CAS:<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Fórmula:C20H16N2O4Pureza:99.52% - 99.88%Cor e Forma:Solid PowderPeso molecular:348.35EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Fórmula:C28H28Cl2N6OCor e Forma:SolidPeso molecular:535.47SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Fórmula:C31H22N2O2Cor e Forma:SolidPeso molecular:454.52CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Fórmula:C35H53N7O7Cor e Forma:SolidPeso molecular:683.84SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Fórmula:C20H25ClN6OCor e Forma:SolidPeso molecular:400.91Merck-22-6
CAS:<p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>Fórmula:C40H43N7O2Cor e Forma:SolidPeso molecular:653.82TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Fórmula:C20H21Cl2NO2Cor e Forma:SolidPeso molecular:378.29CDK/HDAC-IN-2
CAS:<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Fórmula:C25H20Cl2N6O3Cor e Forma:SolidPeso molecular:523.37Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Fórmula:C19H16Cl2N2O3Cor e Forma:SolidPeso molecular:391.25Filanesib
CAS:<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Fórmula:C20H22F2N4O2SPureza:99.8%Cor e Forma:SolidPeso molecular:420.48SKF1
CAS:<p>SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.</p>Fórmula:C23H37ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:409.01Ivaltinostat
CAS:<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Fórmula:C24H33N3O4Pureza:98%Cor e Forma:SolidPeso molecular:427.54AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49NSC745885
CAS:<p>NSC745885 decreases EZH2, has selective cancer cell toxicity, and is studied for bladder and OSCC.</p>Fórmula:C14H6N2O2SPureza:98%Cor e Forma:SolidPeso molecular:266.27bpV(phen)
CAS:<p>bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).</p>Fórmula:C12H8KN2O5VPureza:98%Cor e Forma:SolidPeso molecular:350.24RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H28N8O2Cor e Forma:SolidPeso molecular:496.56Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Fórmula:C18H13ClF3N5OCor e Forma:SolidPeso molecular:407.78PERK-IN-3
CAS:<p>PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).</p>Fórmula:C22H16F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:406.38PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Fórmula:C32H33NO5SCor e Forma:SolidPeso molecular:543.67PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Fórmula:C11H17N5O8Pureza:98%Cor e Forma:SolidPeso molecular:347.28CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Cor e Forma:SolidPeso molecular:392.47Anticancer agent 58
<p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>Fórmula:C39H55NO5Cor e Forma:SolidPeso molecular:617.86hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Fórmula:C23H21Cl2FN2O3Cor e Forma:SolidPeso molecular:463.33GZD856
CAS:<p>GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.</p>Fórmula:C29H27F3N6OPureza:98%Cor e Forma:SolidPeso molecular:532.56Propiomazine
CAS:<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Fórmula:C20H24N2OSPureza:98.5%Cor e Forma:SolidPeso molecular:340.48Jolkinolide B
CAS:<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Fórmula:C20H26O4Pureza:99.39% - 99.7%Cor e Forma:SolidPeso molecular:330.42VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Fórmula:C26H20Cl2F3N5O3S2Cor e Forma:SolidPeso molecular:642.5EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49Apoptotic agent-1
CAS:<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Fórmula:C12H6ClN5O2SCor e Forma:SolidPeso molecular:319.73BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Fórmula:C28H42O5Cor e Forma:SolidPeso molecular:458.63PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Cor e Forma:SolidPeso molecular:374.97TJ08
CAS:<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Fórmula:C22H16FN3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:405.38EP12
CAS:<p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>Fórmula:C26H22FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:427.47(R)-STU104
CAS:<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Fórmula:C18H18O4Pureza:98.91% - 99.42%Cor e Forma:SolidPeso molecular:298.33Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5L6H21
CAS:<p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>Fórmula:C18H18O4Pureza:99.26%Cor e Forma:SolidPeso molecular:298.33PD1-PDL1-IN 1
CAS:<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Fórmula:C14H23N7O6Pureza:98%Cor e Forma:SolidPeso molecular:385.38S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Fórmula:C27H21F3N6OPureza:98%Cor e Forma:SolidPeso molecular:502.49BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Fórmula:C20H21N5OPureza:99.71%Cor e Forma:SolidPeso molecular:347.41Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Fórmula:C22H19N3O5Cor e Forma:SolidPeso molecular:405.4RIP1 kinase inhibitor 7
CAS:<p>RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM.</p>Fórmula:C20H20FN3OPureza:98%Cor e Forma:SolidPeso molecular:337.39RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Fórmula:C20H22N4O3SCor e Forma:SolidPeso molecular:398.48Sibiriline
CAS:<p>Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.</p>Fórmula:C13H10N2OPureza:98%Cor e Forma:SolidPeso molecular:210.23GLUT4-IN-2
CAS:<p>GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.</p>Fórmula:C17H11N3O4S2Pureza:99.90%Cor e Forma:SolidPeso molecular:385.42Tubulin polymerization-IN-31
CAS:<p>Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.</p>Fórmula:C18H13ClFN3Cor e Forma:SolidPeso molecular:325.77CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Fórmula:C33H38F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:609.68Lexibulin dihydrochloride
CAS:<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Fórmula:C24H32Cl2N6O2Pureza:98%Cor e Forma:SolidPeso molecular:507.46DRI-C25441
CAS:<p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>Fórmula:C31H21N3O6Cor e Forma:SolidPeso molecular:531.51PD-1/PD-L1-IN 6
CAS:<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Fórmula:C25H26N2O3Cor e Forma:SolidPeso molecular:402.49CAY10789
CAS:<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Fórmula:C17H15NO2Cor e Forma:SolidPeso molecular:265.31GKK1032B
CAS:<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Fórmula:C32H39NO4Cor e Forma:SolidPeso molecular:501.66E64FC26
CAS:<p>E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.</p>Fórmula:C19H23F3O2Pureza:98.1% - 98.1%Cor e Forma:SolidPeso molecular:340.38NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Fórmula:C17H17ClN2SPureza:99.28%Cor e Forma:SolidPeso molecular:316.85Pim-1 kinase inhibitor 1
CAS:<p>Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.</p>Fórmula:C19H13N3O3Cor e Forma:SolidPeso molecular:331.32DAT-230
CAS:<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Fórmula:C20H21NO2SCor e Forma:SolidPeso molecular:339.45IDT
CAS:<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Fórmula:C8H5NS2Pureza:98%Cor e Forma:SolidPeso molecular:179.26PS121912
CAS:<p>PS121912 is a potent and selective inhibitor of VDR-coactivator.</p>Fórmula:C24H21F3N2OPureza:98%Cor e Forma:SolidPeso molecular:410.43DPQZ
CAS:<p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>Fórmula:C20H17N3OPureza:98%Cor e Forma:SolidPeso molecular:315.37SKLB70326
CAS:<p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>Fórmula:C15H13N3O2SPureza:98%Cor e Forma:SolidPeso molecular:299.35CPI-7c
CAS:<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39MDK-4204
CAS:<p>MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.</p>Fórmula:C31H29FN4OPureza:98%Cor e Forma:SolidPeso molecular:492.59Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Fórmula:C7H4Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:231.04MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Fórmula:C22H17NO4SPureza:98%Cor e Forma:SolidPeso molecular:391.44Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26BMS-242
CAS:<p>BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.</p>Fórmula:C28H35NO4Pureza:98%Cor e Forma:SolidPeso molecular:449.58(S)-Elobixibat
CAS:<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Fórmula:C36H45N3O7S2Cor e Forma:SolidPeso molecular:695.89GY1-22
CAS:<p>GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5AKCI
CAS:<p>AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.</p>Fórmula:C19H27N7OPureza:98%Cor e Forma:SolidPeso molecular:369.46Anti-inflammatory agent 55
CAS:<p>Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression</p>Fórmula:C17H15N3O7Cor e Forma:SolidPeso molecular:373.32PI3K/Akt/mTOR-IN-2
CAS:<p>Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.</p>Fórmula:C17H13F2NOPureza:99.98%Cor e Forma:SolidPeso molecular:285.29Vin-F03
CAS:<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Fórmula:C22H29N3Cor e Forma:SolidPeso molecular:335.49Bcl-2-IN-9
CAS:<p>Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.</p>Fórmula:C27H31N7O3SCor e Forma:SolidPeso molecular:533.65STAT3-IN-10
CAS:<p>STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).</p>Fórmula:C17H13NO5Cor e Forma:SolidPeso molecular:311.29VU 0364739 hydrochloride
CAS:<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Fórmula:C26H28ClFN4O2Pureza:99.36%Cor e Forma:SolidPeso molecular:482.98RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Fórmula:C32H33FN6O4Cor e Forma:SolidPeso molecular:584.64FAK-IN-5
CAS:<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Fórmula:C29H29ClF3N3O4Cor e Forma:SolidPeso molecular:576.01MMP-9-IN-3
CAS:<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Fórmula:C29H25N3O4Cor e Forma:SolidPeso molecular:479.53ZMF-10
CAS:<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Fórmula:C19H17F6N7OCor e Forma:SolidPeso molecular:473.38A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Fórmula:C16H26N4O3Pureza:96.29%Cor e Forma:SolidPeso molecular:322.4αβ-Tubulin-IN-1
CAS:<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Fórmula:C25H19N3O3Cor e Forma:SolidPeso molecular:409.44Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Fórmula:C28H28N2O2Cor e Forma:SolidPeso molecular:424.53Anticancer agent 55
CAS:<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Fórmula:C28H21Br2FN2O2Cor e Forma:SolidPeso molecular:596.294
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