Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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6-(2-Hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine
CAS:Produto Controlado<p>Applications An analogue of Olomoucine (Cat. # O567000) that acts as a potent inhibitor of Cdk 1 (IC50=100nm) and Cdk2 (IC50=80nm). Also displays antiproliferative and proapoptotic effects.<br>References Wermeulen, K., et al.: Leukemia, 16, 299(2002)<br></p>Fórmula:C18H24N6O2Cor e Forma:NeatPeso molecular:356.42Graveoline
CAS:Produto Controlado<p>Applications Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.<br></p>Fórmula:C17H13NO3Cor e Forma:NeatPeso molecular:279.29Santamarine
CAS:<p>Applications Santamarine is a sesquiterpene lactone shows anticancer properties by inhibiting proliferation and inducing apoptosis.<br>References Mehmood, T., et al.: J. Cancer, 8, 1-11 (2017)<br></p>Fórmula:C15H20O3Cor e Forma:NeatPeso molecular:248.32L-Cystathionine
CAS:<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Fórmula:C7H14N2O4SPureza:96.43% - >99.99%Cor e Forma:SolidPeso molecular:222.26NPB
CAS:<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Fórmula:C29H31Cl2N3O2Pureza:99.93%Cor e Forma:SolidPeso molecular:524.48Cot inhibitor-2
CAS:<p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>Fórmula:C26H25Cl2FN8Pureza:98.87%Cor e Forma:SolidPeso molecular:539.43SAR405838
CAS:<p>MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.</p>Fórmula:C29H34Cl2FN3O3Pureza:98.63%Cor e Forma:SolidPeso molecular:562.5Riviciclib hydrochloride
CAS:<p>Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.</p>Fórmula:C21H20ClNO5·HClPureza:99.51%Cor e Forma:SolidPeso molecular:438.3Flurochloridone
CAS:<p>Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.</p>Fórmula:C12H10Cl2F3NOPureza:99.86%Cor e Forma:SolidPeso molecular:312.12Camptothecin
CAS:<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Fórmula:C20H16N2O4Pureza:99.52% - 99.88%Cor e Forma:Solid PowderPeso molecular:348.35Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Fórmula:C22H14Pureza:99.97%Cor e Forma:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Peso molecular:278.35SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Cor e Forma:Orange PowderPeso molecular:568.09hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Fórmula:C13H13N3O6P2SCor e Forma:SolidPeso molecular:401.27IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Fórmula:C22H23N3O3S2Cor e Forma:SolidPeso molecular:441.57MYRA-A
CAS:<p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>Fórmula:C19H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:340.37AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45CCT373566
CAS:<p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.</p>Fórmula:C26H29ClF2N6O3Cor e Forma:SolidPeso molecular:547Apoptotic agent-3
CAS:<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Fórmula:C31H21N5OSCor e Forma:SolidPeso molecular:511.6CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Fórmula:C22H18N2O3Cor e Forma:SolidPeso molecular:358.39BMS-566394
CAS:<p>BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).</p>Fórmula:C22H21F3N4O4Cor e Forma:SolidPeso molecular:462.42p53 Activator 2
CAS:<p>p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.</p>Fórmula:C20H21N5O2Cor e Forma:SolidPeso molecular:363.41p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C29H32F6N4OCor e Forma:SolidPeso molecular:566.58MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Fórmula:C15H13NO5SCor e Forma:SolidPeso molecular:319.33MI-3
CAS:<p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>Fórmula:C18H25N5S2Pureza:98.66% - 99.61%Cor e Forma:SolidPeso molecular:375.55RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Fórmula:C30H30Cl2FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:614.49TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Fórmula:C30H38N6OPureza:98%Cor e Forma:SolidPeso molecular:498.66ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Fórmula:C17H15N3O2Cor e Forma:SolidPeso molecular:293.32EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Fórmula:C28H28Cl2N6OCor e Forma:SolidPeso molecular:535.47DMH2
CAS:<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Fórmula:C27H25N5O2Pureza:98%Cor e Forma:SolidPeso molecular:451.52MI-63
CAS:<p>MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.</p>Fórmula:C29H35Cl2FN4O3Cor e Forma:SolidPeso molecular:577.52Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Fórmula:C27H22ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:487.93TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Fórmula:C25H28F3N3O6Cor e Forma:SolidPeso molecular:523.5GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Fórmula:C24H28N4O3Cor e Forma:SolidPeso molecular:420.5Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Fórmula:C27H26ClNO4Cor e Forma:SolidPeso molecular:463.95RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Fórmula:C22H25FN8OPureza:98.31%Cor e Forma:SolidPeso molecular:436.49CMC2.24
CAS:<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Fórmula:C26H21NO5Cor e Forma:SolidPeso molecular:427.45Antitumor agent-57
CAS:<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Fórmula:C20H15NO5Cor e Forma:SolidPeso molecular:349.34AP23464
CAS:<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Fórmula:C26H30N5O2PCor e Forma:SolidPeso molecular:475.52CZS-241
<p>CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.</p>Fórmula:C26H24ClF2N9OCor e Forma:SolidPeso molecular:551.98AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H28N8O2Cor e Forma:SolidPeso molecular:496.56Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Fórmula:C18H13ClF3N5OCor e Forma:SolidPeso molecular:407.78Topoisomerase II inhibitor 11
CAS:<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Fórmula:C27H21BrCl2N2O2SCor e Forma:SolidPeso molecular:588.34CT-1
CAS:<p>CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.</p>Fórmula:C29H23F3N4OPureza:99.79%Cor e Forma:SolidPeso molecular:500.51CX-5011
CAS:<p>CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].</p>Fórmula:C20H12N4O2Pureza:98%Cor e Forma:SolidPeso molecular:340.33ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Fórmula:C11H13NSeCor e Forma:SolidPeso molecular:238.19DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Fórmula:C22H24N2O3SCor e Forma:SolidPeso molecular:396.5SZM-1209
CAS:<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Fórmula:C31H29F5N4O5S2Pureza:98%Cor e Forma:SolidPeso molecular:696.71PI3Kδ/γ-IN-3
CAS:<p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>Fórmula:C23H20ClN9OCor e Forma:SolidPeso molecular:473.92Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Fórmula:C20H18O5Cor e Forma:SolidPeso molecular:338.35PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Fórmula:C18H9Cl4N5OCor e Forma:SolidPeso molecular:453.11Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Fórmula:C26H23NOCor e Forma:SolidPeso molecular:365.47Anticancer agent 47
CAS:<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Fórmula:C19H14N2O4SCor e Forma:SolidPeso molecular:366.39PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Cor e Forma:SolidPeso molecular:374.97PD1-PDL1-IN 1
CAS:<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Fórmula:C14H23N7O6Pureza:98%Cor e Forma:SolidPeso molecular:385.38S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Fórmula:C27H21F3N6OPureza:98%Cor e Forma:SolidPeso molecular:502.49Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Fórmula:C22H19N3O5Cor e Forma:SolidPeso molecular:405.4Lexibulin dihydrochloride
CAS:<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Fórmula:C24H32Cl2N6O2Pureza:98%Cor e Forma:SolidPeso molecular:507.46YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Fórmula:C25H26N6OCor e Forma:SolidPeso molecular:426.51MEK-IN-5
CAS:<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Fórmula:C29H27FN4O10S2Cor e Forma:SolidPeso molecular:674.67CAY10789
CAS:<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Fórmula:C17H15NO2Cor e Forma:SolidPeso molecular:265.31Benpyrine
CAS:<p>Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.</p>Fórmula:C16H16N6OCor e Forma:SolidPeso molecular:308.34GKK1032B
CAS:<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Fórmula:C32H39NO4Cor e Forma:SolidPeso molecular:501.66Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Fórmula:C21H18F4N2O4Cor e Forma:SolidPeso molecular:438.37HBV-IN-23
CAS:<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Fórmula:C25H27N3O3SCor e Forma:SolidPeso molecular:449.57Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Fórmula:C28H28N2O2Cor e Forma:SolidPeso molecular:424.53UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Fórmula:C15H17Cl2N7O3Pureza:98%Cor e Forma:SolidPeso molecular:414.25BLM-IN-1
CAS:<p>BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.</p>Fórmula:C28H35FN4OCor e Forma:SolidPeso molecular:462.6TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59MCL-1/BCL-2-IN-3
CAS:<p>MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.</p>Fórmula:C27H25BrN2O5SCor e Forma:SolidPeso molecular:569.47MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Fórmula:C23H21Cl2FN2O3Cor e Forma:SolidPeso molecular:463.33PCAF-IN-2
CAS:<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Fórmula:C10H7F3N6Cor e Forma:SolidPeso molecular:268.2STAT3-IN-3
CAS:<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Fórmula:C27H26BrN3O6SPureza:98%Cor e Forma:SolidPeso molecular:600.48Tubulin polymerization-IN-31
CAS:<p>Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.</p>Fórmula:C18H13ClFN3Cor e Forma:SolidPeso molecular:325.77CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Fórmula:C33H38F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:609.68Ormeloxifene
CAS:estrogen receptor modulatorFórmula:C30H35NO3Pureza:98%Cor e Forma:SolidPeso molecular:457.6Fenoldopam hydrochloride
CAS:<p>Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.</p>Fórmula:C16H17Cl2NO3Cor e Forma:SolidPeso molecular:342.22Telomerase-IN-4
CAS:<p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>Fórmula:C21H18N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:406.52Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58MI-1061
CAS:<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Fórmula:C30H26Cl2FN3O4Cor e Forma:SolidPeso molecular:582.45CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Fórmula:C23H18BrN3OSPureza:98%Cor e Forma:SolidPeso molecular:464.38IMM-H004
CAS:<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Fórmula:C16H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:304.34BTK-IN-24
CAS:<p>BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.</p>Fórmula:C26H19F4N5O2Pureza:99.61%Cor e Forma:SolidPeso molecular:509.46ZINC69391
CAS:<p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>Fórmula:C14H14F3N5Pureza:99.61%Cor e Forma:SolidPeso molecular:309.29BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Fórmula:C20H21N5OPureza:99.71%Cor e Forma:SolidPeso molecular:347.41RETRA
CAS:<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Fórmula:C11H12BrNO3S2Pureza:98%Cor e Forma:SolidPeso molecular:350.25Norartocarpetin
CAS:<p>Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.</p>Fórmula:C15H10O6Cor e Forma:SolidPeso molecular:286.24Flupenthixol
CAS:<p>Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.</p>Fórmula:C23H25F3N2OSPureza:98%Cor e Forma:SolidPeso molecular:434.52HDAC-IN-39
CAS:<p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>Fórmula:C27H26N4O4SCor e Forma:SolidPeso molecular:502.58BMS-1166 hydrochloride
CAS:<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Fórmula:C36H34Cl2N2O7Pureza:98%Cor e Forma:SolidPeso molecular:677.57IV-23
CAS:<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Fórmula:C18H18BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:392.24HS56
CAS:<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Fórmula:C13H8ClN5OSCor e Forma:SolidPeso molecular:317.75Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Fórmula:C20H21Cl2NO2Cor e Forma:SolidPeso molecular:378.29Filanesib
CAS:<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Fórmula:C20H22F2N4O2SPureza:99.8%Cor e Forma:SolidPeso molecular:420.48Imofinostat
CAS:<p>Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.</p>Fórmula:C17H16N2O4SCor e Forma:SolidPeso molecular:344.38BCL6-IN-8c
CAS:<p>BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent</p>Fórmula:C20H20ClN3O5Cor e Forma:SolidPeso molecular:417.84Ivaltinostat
CAS:<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Fórmula:C24H33N3O4Pureza:98%Cor e Forma:SolidPeso molecular:427.54TP-472
CAS:<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Fórmula:C20H19N3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.38GW7845
CAS:<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Fórmula:C29H28N2O6Pureza:98%Cor e Forma:SolidPeso molecular:500.54Anticancer agent 77
CAS:<p>Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.</p>Fórmula:C25H30BrN7Cor e Forma:SolidPeso molecular:508.46RIPK3-IN-2
CAS:<p>RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.</p>Fórmula:C21H16ClN3O2S2Cor e Forma:SolidPeso molecular:441.95Flunisolide hemihydrate
CAS:<p>Flunisolide hemihydrate, a corticosteroid with anti-inflammatory properties, treats asthma and rhinitis by inducing eosinophil apoptosis.</p>Fórmula:C48H64F2O13Cor e Forma:SolidPeso molecular:887.024Anticancer agent 66
CAS:<p>Anticancer agent 66, a ciprofloxacin analog, triggers apoptosis in MCF-7 cells.</p>Fórmula:C26H23Cl2FN6O2S2Cor e Forma:SolidPeso molecular:605.53Nutlin-1
CAS:<p>Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.</p>Fórmula:C32H34Cl2N4O4Cor e Forma:SolidPeso molecular:609.54NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Fórmula:C17H17ClN2SPureza:99.28%Cor e Forma:SolidPeso molecular:316.85HDAC1/2 and CDK2-IN-1
CAS:<p>Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.</p>Fórmula:C26H22ClN7OCor e Forma:SolidPeso molecular:483.95PDE4-IN-10
CAS:<p>PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.</p>Fórmula:C18H13NCor e Forma:SolidPeso molecular:243.3Quinate
CAS:<p>Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.</p>Fórmula:C26H36N2O9Cor e Forma:SolidPeso molecular:520.579Anticancer agent 59
<p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>Fórmula:C42H59NO6Cor e Forma:SolidPeso molecular:673.92SS28
CAS:<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Fórmula:C18H20O3Pureza:98%Cor e Forma:SolidPeso molecular:284.35MI-389
CAS:<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Fórmula:C35H35FN6O6Pureza:98.12%Cor e Forma:SolidPeso molecular:654.69Oxythiamine chloride HCl
CAS:<p>Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.</p>Fórmula:C12H17Cl2N3O2SCor e Forma:SolidPeso molecular:338.25CAM 833
CAS:<p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>Fórmula:C26H26ClFN4O5Pureza:99.83%Cor e Forma:SolidPeso molecular:528.96Esuberaprost Sodium
CAS:<p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>Fórmula:C23H27FN4O2Cor e Forma:SolidPeso molecular:410.48Vin-C01
CAS:<p>Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.</p>Fórmula:C20H24N2OCor e Forma:SolidPeso molecular:308.42SMBA1
CAS:<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32VRT-043198
CAS:<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Fórmula:C22H29ClN4O6Cor e Forma:SolidPeso molecular:480.94PAK4-IN-2
CAS:<p>PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.</p>Fórmula:C18H21ClN6Cor e Forma:SolidPeso molecular:356.85Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Cor e Forma:SolidPeso molecular:592.69CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Fórmula:C11H9N3O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:247.21PD180970
CAS:<p>PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.</p>Fórmula:C21H15Cl2FN4OPureza:98.67%Cor e Forma:SolidPeso molecular:429.27LLL3
CAS:<p>LLL3 is a small molecule STAT3 inhibitor.</p>Fórmula:C16H10O4Cor e Forma:SolidPeso molecular:266.25GRI977143
CAS:<p>GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.</p>Fórmula:C22H17NO4SPureza:98.07%Cor e Forma:SolidPeso molecular:391.44BR102375
CAS:<p>BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.</p>Fórmula:C31H34N6O4Pureza:98%Cor e Forma:SolidPeso molecular:554.64Antitumor agent-44
CAS:<p>Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human</p>Fórmula:C24H15N3O3Cor e Forma:SolidPeso molecular:393.39RET-IN-12
CAS:<p>RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).</p>Fórmula:C30H30F3N5O4Cor e Forma:SolidPeso molecular:581.59VU 0364739 hydrochloride
CAS:<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Fórmula:C26H28ClFN4O2Pureza:99.36%Cor e Forma:SolidPeso molecular:482.98Topoisomerase I inhibitor 5
CAS:<p>Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.</p>Fórmula:C24H24N2O2Cor e Forma:SolidPeso molecular:372.46KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3NSC260594
CAS:<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Fórmula:C29H24N6O3Cor e Forma:SolidPeso molecular:504.54USP7-IN-4
CAS:<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Fórmula:C29H34N6O3Pureza:98.27% - 99.09%Cor e Forma:SolidPeso molecular:514.62ICG-001
CAS:<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Fórmula:C33H32N4O4Pureza:99.55% - 99.62%Cor e Forma:SolidPeso molecular:548.63Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Fórmula:C26H25N3O6SCor e Forma:SolidPeso molecular:507.56PD-1/PD-L1-IN-28
CAS:<p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>Fórmula:C24H24N4O2Cor e Forma:SolidPeso molecular:400.47Anti-inflammatory agent 17
CAS:<p>Compound 17: Orally active, potent IL-6 & TNF-α inhibitor; not cytotoxic; promising for ALI research.</p>Fórmula:C20H23NO5Cor e Forma:SolidPeso molecular:357.4HS-438
CAS:<p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>Fórmula:C17H17N3O3SCor e Forma:SolidPeso molecular:343.4EGFR-IN-56
CAS:<p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>Fórmula:C23H22N4O3SCor e Forma:SolidPeso molecular:434.51Topoisomerase IIα-IN-3
CAS:<p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>Fórmula:C29H20N6O2SCor e Forma:SolidPeso molecular:516.57MBM-17
CAS:<p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>Fórmula:C28H28N6O2Pureza:98%Cor e Forma:SolidPeso molecular:480.56VU0285655-1
CAS:<p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>Fórmula:C25H27N5O2Pureza:99.73%Cor e Forma:SolidPeso molecular:429.51EL-102
CAS:<p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>Fórmula:C19H16N2O3S2Pureza:99.34%Cor e Forma:SolidPeso molecular:384.47EGFR-IN-46
CAS:<p>EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.</p>Fórmula:C27H32F3N3O3Cor e Forma:SolidPeso molecular:503.56DX2-201
CAS:<p>DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.</p>Fórmula:C18H28N2O6S2Cor e Forma:SolidPeso molecular:432.55Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Fórmula:C20H34O5Pureza:97.94% - 98.04%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:354.48FKGK 18
CAS:<p>FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.</p>Fórmula:C16H15F3OCor e Forma:SolidPeso molecular:280.28NSC-741909
CAS:<p>NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.</p>Fórmula:C16H14ClNOPureza:98%Cor e Forma:SolidPeso molecular:271.74CPI-7c
CAS:<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39NU-8165
CAS:<p>NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.</p>Fórmula:C24H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:407.89RC-33 HCl
CAS:<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Fórmula:C21H28ClNPureza:98%Cor e Forma:SolidPeso molecular:329.91SMBA2
CAS:<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Fórmula:C8H16N4Pureza:98%Cor e Forma:SolidPeso molecular:168.24D44
CAS:<p>D44 is a Plasmodium FKBPs inhibitor.</p>Fórmula:C16H16N4OSCor e Forma:SolidPeso molecular:312.39Tryptophanamide
CAS:<p>Tryptophanamide is a chymotrypsin inhibitor.</p>Fórmula:C11H13N3OPureza:98%Cor e Forma:SolidPeso molecular:203.24NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Fórmula:C17H12F3NO3Pureza:99.981%Cor e Forma:SolidPeso molecular:335.28Ozarelix
CAS:<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Fórmula:C72H96ClN17O14Cor e Forma:SolidPeso molecular:1459.09Mitochonic Acid 35
CAS:<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Fórmula:C19H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:341.36Lemuteporfin
CAS:<p>Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.</p>Fórmula:C44H48N4O10Pureza:97.14% - 99.44%Cor e Forma:SolidPeso molecular:792.87RIPK1-IN-12
CAS:<p>RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).</p>Fórmula:C24H26N4O3SCor e Forma:SolidPeso molecular:450.55NSC-639829
CAS:<p>NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.</p>Fórmula:C21H20BrN5O3Pureza:99.53% - 99.77%Cor e Forma:SolidPeso molecular:470.32(S)-Elobixibat
CAS:<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Fórmula:C36H45N3O7S2Cor e Forma:SolidPeso molecular:695.89ABD56
CAS:<p>ABD56 inhibits osteoclast formation and activity in vitro and in vivo.</p>Fórmula:C17H18O3Cor e Forma:SolidPeso molecular:270.32MeOIstPyrd
CAS:<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Fórmula:C14H16N4O2SCor e Forma:SolidPeso molecular:304.37Tubulin polymerization-IN-14
CAS:<p>Tubulin-IN-14 (20a) inhibits polymerization (IC50=3.15μM), has anti-cancer and anti-vascular effects, inducing cell death.</p>Fórmula:C15H15ClN2O2Cor e Forma:SolidPeso molecular:290.74HDAC-IN-42
CAS:<p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.</p>Fórmula:C20H15NO7Cor e Forma:SolidPeso molecular:381.34Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Fórmula:C24H21ClF3N5OPureza:98.95% - 99.38%Cor e Forma:SolidPeso molecular:487.9Theophylline sodium glycinate
CAS:<p>Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.</p>Fórmula:C9H12N5NaO4Cor e Forma:SolidPeso molecular:277.216RET-IN-16
CAS:<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Fórmula:C31H29F3N8O2Cor e Forma:SolidPeso molecular:602.61SEC
CAS:<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Fórmula:C22H23ClN2O5Cor e Forma:SolidPeso molecular:430.88FD223
CAS:<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Fórmula:C17H12ClN5O2SCor e Forma:SolidPeso molecular:385.83CAY10773
CAS:<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Fórmula:C22H17Cl2N5OCor e Forma:SolidPeso molecular:438.31CAY10503
CAS:<p>CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.</p>Fórmula:C18H14O3Cor e Forma:SolidPeso molecular:278.3MMP-9-IN-3
CAS:<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Fórmula:C29H25N3O4Cor e Forma:SolidPeso molecular:479.53ZMF-10
CAS:<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Fórmula:C19H17F6N7OCor e Forma:SolidPeso molecular:473.38Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Fórmula:C29H38FN3O5Pureza:97.07% - 98.07%Cor e Forma:SolidPeso molecular:527.63αβ-Tubulin-IN-1
CAS:<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Fórmula:C25H19N3O3Cor e Forma:SolidPeso molecular:409.44Tigilanol tiglate
CAS:<p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>Fórmula:C30H42O10Pureza:98%Cor e Forma:SolidPeso molecular:562.65MX107
CAS:<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Fórmula:C24H28N2O2Cor e Forma:SolidPeso molecular:376.492'-Deoxyadenosine
CAS:<p>2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.</p>Fórmula:C10H13N5O3Pureza:99.71%Cor e Forma:SolidPeso molecular:251.24HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Fórmula:C27H24N4O2Pureza:97.19%Cor e Forma:SolidPeso molecular:436.51GW837016X
CAS:<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Fórmula:C25H20ClFN4OSCor e Forma:SolidPeso molecular:478.97Anti-inflammatory agent 47
CAS:<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Fórmula:C25H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:394.42PHA-680626
CAS:<p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>Fórmula:C23H26N6O2SCor e Forma:SolidPeso molecular:450.56LG308
CAS:<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Fórmula:C19H17FN2OCor e Forma:SolidPeso molecular:308.35Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Fórmula:C25H21ClN2O5Cor e Forma:SolidPeso molecular:464.9A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Fórmula:C16H26N4O3Pureza:96.29%Cor e Forma:SolidPeso molecular:322.4PI3Kδ-IN-11
CAS:<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Fórmula:C27H21N5OCor e Forma:SolidPeso molecular:431.49PI3K-IN-33
CAS:<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Fórmula:C23H21BrN6O2Cor e Forma:SolidPeso molecular:493.36VEGFR-2-IN-22
CAS:<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Fórmula:C26H24ClFN4O6Cor e Forma:SolidPeso molecular:542.94AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Fórmula:C17H15N5SCor e Forma:SolidPeso molecular:321.4ORY-1001 free base
CAS:<p>ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).</p>Fórmula:C15H22N2Pureza:98%Cor e Forma:SolidPeso molecular:230.35Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Fórmula:C31H34Cl2N6O3P2RuCor e Forma:SolidPeso molecular:772.56CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Cor e Forma:SolidPeso molecular:261.27PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Fórmula:C16H10Cl2N2OSPureza:98%Cor e Forma:SolidPeso molecular:349.23PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Fórmula:C20H22N6O4Pureza:98%Cor e Forma:SolidPeso molecular:410.43ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Fórmula:C24H32N4O3Cor e Forma:SolidPeso molecular:424.54PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5
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