Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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Desloratadine
CAS:<p>Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties.</p>Fórmula:C19H19ClN2Pureza:99.79% - >99.99%Cor e Forma:SolidPeso molecular:310.82Rosiglitazone potassium
CAS:<p>Rosiglitazone (BRL 49653) is an oral PPARγ agonist (EC50: 60 nM), TRPC5 activator (EC50: 30 μM), and TRPM3 inhibitor, used in obesity and diabetes research.</p>Fórmula:C18H18KN3O3SCor e Forma:SolidPeso molecular:395.52Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Cor e Forma:SolidPeso molecular:507.56Vandetanib trifluoroacetate
CAS:<p>Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).</p>Fórmula:C24H25BrF4N4O4Cor e Forma:SolidPeso molecular:589.386Sulindac sodium
CAS:<p>Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.</p>Fórmula:C20H16FNaO3SCor e Forma:SolidPeso molecular:378.39Fenobam hydrate
CAS:<p>Fenobam hydrate blocks mGluR5, preventing calcium mobilization, and may reduce stress, anxiety, and pain.</p>Fórmula:C11H13ClN4O3Cor e Forma:SolidPeso molecular:284.7Chloropyramine
CAS:<p>Chloropyramine: H1 antagonist for allergies like conjunctivitis, asthma; has anti-breast cancer properties.</p>Fórmula:C16H20ClN3Cor e Forma:SolidPeso molecular:289.8Brusatol
CAS:<p>Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.</p>Fórmula:C26H32O11Pureza:99.35% - 99.95%Cor e Forma:SolidPeso molecular:520.53Gefitinib dihydrochloride
CAS:<p>Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.</p>Fórmula:C22H26Cl3FN4O3Cor e Forma:SolidPeso molecular:519.82Rafoxanide
CAS:<p>Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.</p>Fórmula:C19H11Cl2I2NO3Pureza:99.47%Cor e Forma:Slight Yellowish Brown Injectable Solution &White Oral SolutionPeso molecular:626.01Pyrazoloadenine
CAS:<p>Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.</p>Fórmula:C5H5N5Pureza:99.02%Cor e Forma:Beige PowderPeso molecular:135.13Tomivosertib HCl
CAS:<p>Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.</p>Fórmula:C17H21ClN6O2Cor e Forma:SolidPeso molecular:376.845YUM70
CAS:<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Fórmula:C21H19ClN2O4Pureza:97.25%Cor e Forma:SolidPeso molecular:398.84Lanreotide acetate
CAS:<p>Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome</p>Fórmula:C56H73N11O12S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:1156.39CHIR-124
CAS:<p>CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.</p>Fórmula:C23H22ClN5OPureza:96.33% - 98.35%Cor e Forma:SolidPeso molecular:419.91Tangeretin
CAS:<p>Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective</p>Fórmula:C20H20O7Pureza:98.83% - 98.97%Cor e Forma:Yellow CrystallinePeso molecular:372.37Torkinib
CAS:<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Fórmula:C16H16N6OPureza:99.11%Cor e Forma:SolidPeso molecular:308.34Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Fórmula:C20H21N5O6·2NaH2OPureza:98.76%Cor e Forma:SolidPeso molecular:518.43Volasertib trihydrochloride
CAS:<p>Volasertib (BI 6727), a potent PLK1 inhibitor (IC50: 0.87 nM), also targets PLK2 and PLK3, causes mitotic arrest, apoptosis, and anticancer effects.</p>Fórmula:C34H53Cl3N8O3Cor e Forma:SolidPeso molecular:728.2Moexipril hydrochloride
CAS:<p>Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of</p>Fórmula:C27H34N2O7·HClPureza:97.8%Cor e Forma:A Fine White To Off-White PowderPeso molecular:535.03SKLB4771
CAS:<p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>Fórmula:C25H27N7O3S2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:537.66HLCL-61 hydrochloride
CAS:<p>HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.</p>Fórmula:C23H24N2O·ClHPureza:99.88% - 99.95%Cor e Forma:SolidPeso molecular:380.914-Hydroxybenzyl alcohol
CAS:<p>4-Hydroxybenzyl alcohol aids brain injury recovery, boosts Nrf2/Prdx6/PDI, and hinders angiogenesis, showing promise in cancer therapy.</p>Fórmula:C7H8O2Pureza:97.65% - 98.25%Cor e Forma:SolidPeso molecular:124.14Rilmenidine hemifumarate
CAS:<p>Rilmenidine hemifumarate (S-3341 hemifumarate) is an I1 imidazoline receptor and α2-adrenergic receptor agonist that induces autophagy.</p>Fórmula:C10H16N2OC4H4O4Pureza:98.14%Cor e Forma:SolidPeso molecular:238.28AX-024
CAS:<p>AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.</p>Fórmula:C21H22FNO2Cor e Forma:SolidPeso molecular:339.4Zorifertinib
CAS:<p>Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.</p>Fórmula:C22H23ClFN5O3Pureza:98.20% - 99.36%Cor e Forma:White To Off-White SolidPeso molecular:459.9TD52
CAS:<p>TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.</p>Fórmula:C24H16N4Pureza:99.5%Cor e Forma:SolidPeso molecular:360.41ABT-751
CAS:<p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Cor e Forma:SolidPeso molecular:371.41cjoc42
CAS:<p>Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.</p>Fórmula:C20H21N3O5SPureza:99.56%Cor e Forma:SolidPeso molecular:415.46Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Fórmula:C16H12ClNOPureza:99.75%Cor e Forma:SolidPeso molecular:269.73Bioymifi
CAS:<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>Fórmula:C22H12BrN3O4SPureza:98% - 99.79%Cor e Forma:SolidPeso molecular:494.32OTS514
CAS:OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.Fórmula:C21H20N2O2SPureza:99.62%Cor e Forma:SolidPeso molecular:364.462,4,6-Triiodophenol
CAS:<p>2,4,6-Triiodophenol: iodinated byproduct from sewage chlorination, disrupts thyroid function, used to study deiodinase.</p>Fórmula:C6H3I3OPureza:98.11%Cor e Forma:Grey To Tan To Brown PowderPeso molecular:471.84'-bromo-Resveratrol
CAS:<p>4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)</p>Fórmula:C14H11BrO2Pureza:99.00%Cor e Forma:SolidPeso molecular:291.142-Methoxyestradiol
CAS:<p>2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.</p>Fórmula:C19H26O3Pureza:98% - 99.95%Cor e Forma:Off-White SolidPeso molecular:302.41UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Cor e Forma:SolidPeso molecular:471.66Ibandronate sodium monohydrate
CAS:<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Fórmula:C9H24NNaO8P2Pureza:99.62%Cor e Forma:White Crystalline PowderPeso molecular:359.23Bufotalin
CAS:<p>1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.</p>Fórmula:C26H36O6Pureza:99.45% - 99.91%Cor e Forma:White To Off-White SolidPeso molecular:444.56JG-98
CAS:<p>JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM).</p>Fórmula:C24H21Cl2N3OS3Pureza:99.13%Cor e Forma:SolidPeso molecular:534.53Bomedemstat
CAS:<p>Bomedemstat (IMG-7289),Irreversible LSD1 inhibitor. Active in MPN models. Antineoplastic effects. Used in AML and myelofibrosis research.</p>Fórmula:C28H34FN7O2Pureza:99.00%Cor e Forma:SolidPeso molecular:519.61BI-3802
CAS:<p>BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM.</p>Fórmula:C24H29ClN6O3Pureza:97.93% - 98.58%Cor e Forma:SolidPeso molecular:484.98Nodinitib-1
CAS:<p>Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.</p>Fórmula:C14H13N3O2SPureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:287.34Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Fórmula:C21H17Cl3N4OSPureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:479.81Polygalacin D
CAS:<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Fórmula:C57H92O27Pureza:98.95% - ≥98%Cor e Forma:SolidPeso molecular:1209.4m-3M3FBS
CAS:<p>m-3M3FBS is a phospholipase C (PLC) activator.</p>Fórmula:C16H16F3NO2SPureza:99.66%Cor e Forma:SolidPeso molecular:343.36Isoliensinine
CAS:<p>Isoliensinine (Isoliensinin) is a natural product, a bisbenzylisoquinoline alkaloid. Isoliensinine has antitumor and antioxidant effects. Cost effective and quality assured.</p>Fórmula:C37H42N2O6Pureza:98.53% - 99.79%Cor e Forma:SolidPeso molecular:610.74ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Cor e Forma:SolidPeso molecular:375.47Evocarpine
CAS:<p>Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.</p>Fórmula:C23H33NOPureza:99.77% - 99.819%Cor e Forma:SolidPeso molecular:339.51Bacopaside II
CAS:<p>Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.</p>Fórmula:C47H76O18Pureza:98.14% - 99.86%Cor e Forma:SolidPeso molecular:929.1Thalidomide-NH-C2-PEG3-OH
CAS:<p>Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase</p>Fórmula:C21H27N3O8Pureza:99.06%Cor e Forma:SolidPeso molecular:449.45
