Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Fórmula:C45H50ClN7O7SPureza:98.00% - 99.97%Cor e Forma:SolidPeso molecular:868.44Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Fórmula:C14H19Br2ClN4SPureza:99.86%Cor e Forma:SolidPeso molecular:470.7SSE15206
CAS:<p>SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.</p>Fórmula:C19H21N3O3SPureza:98.81%Cor e Forma:SolidPeso molecular:371.45Tacedinaline
CAS:<p>Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.</p>Fórmula:C15H15N3O2Pureza:96.83% - 99.15%Cor e Forma:WhitePeso molecular:269.3Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Fórmula:C24H30N6O2Pureza:98.87%Cor e Forma:SolidPeso molecular:434.53Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:608.72OTS964 hydrochloride
CAS:<p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>Fórmula:C23H24N2O2S·HClPureza:96.5% - 98.03%Cor e Forma:SolidPeso molecular:428.97AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Fórmula:C27H32N6Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:440.583-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96Pitstop 2
CAS:<p>Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain. Pitstop2 has antitumor activity. Cost-effective, quality assurance.</p>Fórmula:C20H13BrN2O3S2Pureza:99.54%Cor e Forma:SolidPeso molecular:473.36Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Fórmula:C6H6O7Cor e Forma:SolidPeso molecular:190.11Rosiglitazone potassium
CAS:<p>Rosiglitazone (BRL 49653) is an oral PPARγ agonist (EC50: 60 nM), TRPC5 activator (EC50: 30 μM), and TRPM3 inhibitor, used in obesity and diabetes research.</p>Fórmula:C18H18KN3O3SCor e Forma:SolidPeso molecular:395.52Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Cor e Forma:White To Off-White PowderPeso molecular:362.46Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Fórmula:C22H22O7Pureza:99.65% - 99.84%Cor e Forma:SolidPeso molecular:398.413-O-Methylgallic acid
CAS:<p>3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and</p>Fórmula:C8H8O5Pureza:99.56%Cor e Forma:SolidPeso molecular:184.15Ferrostatin-1
CAS:<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Cor e Forma:SolidPeso molecular:262.35Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Fórmula:C14H21N3OPureza:99.53% - 99.87%Cor e Forma:SolidPeso molecular:247.34Thalidomide-NH-CH2-COOH
CAS:<p>Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a</p>Fórmula:C15H13N3O6Pureza:96.3800%Cor e Forma:SolidPeso molecular:331.28CVT-11127
CAS:<p>CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.</p>Fórmula:C25H23Cl2N5O3Pureza:98.32%Cor e Forma:SolidPeso molecular:512.39Trolox
CAS:<p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>Fórmula:C14H18O4Pureza:98.90% - 99.90%Cor e Forma:White To Fainly Beige Crystalline PowderPeso molecular:250.29Grape Seed Extract
CAS:<p>Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.</p>Fórmula:C32H30O11Pureza:98%Cor e Forma:SolidPeso molecular:590.581Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:<p>Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-</p>Fórmula:C17H21ClN4O5Pureza:97.13%Cor e Forma:SolidPeso molecular:396.83R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Cor e Forma:SolidPeso molecular:369.22PF-3758309 dihydrochloride
<p>PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.</p>Fórmula:C25H32Cl2N8OSCor e Forma:SolidPeso molecular:563.55Atopaxar hydrochloride
CAS:<p>Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.</p>Fórmula:C29H39ClFN3O5Cor e Forma:SolidPeso molecular:564.1WM-3835
CAS:<p>WM-3835, a specific KAT7 inhibitor, potently halts OS cell growth, migration, and induces apoptosis.</p>Fórmula:C20H17FN2O4SPureza:97.78% - 99.36%Cor e Forma:SolidPeso molecular:400.42Chromium picolinate
CAS:<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Fórmula:C18H12CrN3O6Pureza:99.64%Cor e Forma:Violet-Red Crystalline PowderPeso molecular:418.30ZZW-115 hydrochloride
CAS:<p>ZZW-115 hydrochloride inhibits the activity of NUPR1.</p>Fórmula:C24H34Cl3F3N4SPureza:99.97%Cor e Forma:SolidPeso molecular:573.97Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Cor e Forma:Off-White PowderPeso molecular:466.53Perifosine
CAS:<p>Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.</p>Fórmula:C25H52NO4PPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:461.66Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Cor e Forma:SolidPeso molecular:467.39Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:<p>Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase</p>Fórmula:C5H14Cl2N4O3Pureza:99.12% - 99.84%Cor e Forma:SolidPeso molecular:249.10TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Fórmula:C10H14O2Pureza:99.17% - 99.53%Cor e Forma:White Solid PowderPeso molecular:166.22Sulindac sodium
CAS:<p>Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.</p>Fórmula:C20H16FNaO3SCor e Forma:SolidPeso molecular:378.39Ganoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Cor e Forma:SolidPeso molecular:514.65Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Fórmula:C36H62O8Pureza:99.20% - 99.76%Cor e Forma:White PowderPeso molecular:622.87SecinH3
CAS:<p>SecinH3 is selective cytohesin inhibitor.</p>Fórmula:C24H20N4O4SPureza:97.49% - 99.37%Cor e Forma:SolidPeso molecular:460.51AZ960
CAS:<p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).</p>Fórmula:C18H16F2N6Pureza:96.02% - 98.51%Cor e Forma:SolidPeso molecular:354.36Sulforaphane
CAS:<p>Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.</p>Fórmula:C6H11NOS2Pureza:95% - 99.79%Cor e Forma:Light Yellow LiquidPeso molecular:177.29Fimepinostat
CAS:<p>Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.</p>Fórmula:C23H24N8O4SPureza:98.27% - 99.87%Cor e Forma:SolidPeso molecular:508.55Ipatasertib
CAS:<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Fórmula:C24H32ClN5O2Pureza:98.28% - 99.21%Cor e Forma:SolidPeso molecular:458CCCP
CAS:<p>CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.</p>Fórmula:C9H5ClN4Pureza:97.15% - 99.64%Cor e Forma:Yellow To Orange PowderPeso molecular:204.62NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Cor e Forma:SolidPeso molecular:242.28Almorexant
CAS:<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Cor e Forma:SolidPeso molecular:512.56Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:625.56Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Cor e Forma:SolidPeso molecular:581.49Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Cor e Forma:White Crystalline Granular OdorlessPeso molecular:299.66
