Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6222 produtos de "Apoptose"
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N-deacetylated BMS-202
CAS:N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interaction with potential anticancer activity for cancer research.Fórmula:C23H27N3O2Pureza:98.13% - 99.58%Cor e Forma:SolidPeso molecular:377.48Busulfan-d8
CAS:Busulfan-d8 (Sulphabutin-d8) is the 2H-labeled Busulfan. Busulfan is an anticancer agent with immunosuppressive and myeloablative chemotherapy activities.Fórmula:C6H6D8O6S2Cor e Forma:SolidPeso molecular:254.35Citrinin (Standard)
CAS:Citrinin (Standard) is the standard substance of Citrinin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Citrinin is a mycotoxin that causes contamination in the food and is associated with different toxic effects. Citrinin also possesses a broad spectrum of bioactivities, including antifungal, antibacterial, and potential anticancer and neuroprotective effects in vitro.Fórmula:C13H14O5Peso molecular:250.25Terfenadine (Standard)
CAS:Terfenadine (Standard) is the standard substance of Terfenadine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.Fórmula:C32H41NO2Peso molecular:471.67Pyridoclax
CAS:Pyridoclax is an inhibitor of potential Mcl-1.Fórmula:C29H22N4Pureza:98%Cor e Forma:SolidPeso molecular:426.51Saquinavir mesylate
CAS:Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFórmula:C39H54N6O8SPureza:99.19%Cor e Forma:White Or Pale Yellow PowderPeso molecular:766.9Deferasirox (Fe3+ chelate)
CAS:Deferasirox (Fe3+ chelate) is an iron chelator with anticancer activity and can be used to study iron overload.Fórmula:C21H12FeN3O4Pureza:≥98.0%Cor e Forma:SolidPeso molecular:426.18Taltirelin
CAS:Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase inFórmula:C17H23N7O5Pureza:98%Cor e Forma:SolidPeso molecular:405.41Apremilast-d5
CAS:Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast.Fórmula:C22H24N2O7SCor e Forma:SolidPeso molecular:465.535-Methoxyuridine
CAS:5-Methoxyuridine (Mo5U) is an antitumor purine analog that inhibits DNA synthesis and induces apoptosis in lymphatic cancers.
Fórmula:C10H14N2O7Pureza:99.43%Cor e Forma:SolidPeso molecular:274.23Furazolidone (Standard)
CAS:Furazolidone (Standard) is the standard substance of Furazolidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,Fórmula:C8H7N3O5Peso molecular:225.16Etoposide Phosphate
CAS:Etoposide Phosphate is a selective and orally active topoisomerase II inhibitor and anticancer chemotherapy drug that apoptosise, the p53, and G2/MFórmula:C29H33O16PCor e Forma:SolidPeso molecular:668.54K 858
CAS:Fórmula:C13H15N3O2SPureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:277.34Chlorhexidine digluconate
CAS:Chlorhexidine digluconate is a disinfectant with antibacterial activity that induces apoptosis and can be used to study bacterial infections.Fórmula:C34H54Cl2N10O14Pureza:98.53%Cor e Forma:Less To Pale Yellow Clear Liquid Colorless To Pale Yellow Clear LiquidPeso molecular:897.76Echinocystic acid
CAS:EA, a natural triterpene, is found in herbs; it has anti-inflammatory and antioxidant properties.Fórmula:C30H48O4Pureza:98% - 99.57%Cor e Forma:SolidPeso molecular:472.70FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Fórmula:C18H13N7Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:327.34Ref: TM-T1956
1mg40,00€2mg52,00€5mg81,00€1mL*10mM (DMSO)89,00€10mg131,00€25mg210,00€50mg314,00€100mg470,00€MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Cor e Forma:SolidPeso molecular:431.91Garcinol
CAS:Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).Fórmula:C38H50O6Pureza:98.59%Cor e Forma:SolidPeso molecular:602.8VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Fórmula:C19H17ClN2O5Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:388.8Ref: TM-T2258
1mg39,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg150,00€25mg250,00€50mg384,00€100mg557,00€200mg787,00€Panobinostat
CAS:Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43Ref: TM-T2383
5mg35,00€1mL*10mM (DMSO)52,00€10mg54,00€25mg82,00€50mg100,00€100mg137,00€200mg168,00€500mg344,00€AS1842856
CAS:AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Fórmula:C18H22FN3O3Pureza:99.36% - >99.99%Cor e Forma:SolidPeso molecular:347.38HS-1793
CAS:HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.Fórmula:C16H12O3Pureza:98.16% - 99.82%Cor e Forma:SolidPeso molecular:252.26Scopoletin
CAS:Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).Fórmula:C10H8O4Pureza:97.06% - 99.88%Cor e Forma:Yellow To Beige Crystalline PowderPeso molecular:192.17Necrostatin 2 racemate
CAS:Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.Fórmula:C13H12ClN3O2Pureza:98% - 99.5%Cor e Forma:SolidPeso molecular:277.71Ref: TM-T7504
1mg62,00€5mg102,00€1mL*10mM (DMSO)133,00€10mg160,00€25mg289,00€50mg500,00€100mg705,00€500mg1.431,00€Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Fórmula:C26H22N2O2Pureza:97.12% - 99.96%Cor e Forma:SolidPeso molecular:394.47Ref: TM-T6671
2mg40,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg88,00€25mg170,00€50mg324,00€100mg482,00€500mg1.063,00€Pralsetinib
CAS:Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918TFórmula:C27H32FN9O2Pureza:97.88% - 99.8%Cor e Forma:SolidPeso molecular:533.6TVB-3166
CAS:TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).Fórmula:C24H24N4OPureza:99.53% - 99.57%Cor e Forma:SolidPeso molecular:384.47Ref: TM-T17180
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg195,00€50mg334,00€100mg500,00€Selpercatinib
CAS:"Selpercatinib (LOXO-292) is a RET tyrosine kinase inhibitor with IC50s of 14.0, 24.1, 530.7 nM for different RET mutations."Fórmula:C29H31N7O3Pureza:99.89% - >99.99%Cor e Forma:SolidPeso molecular:525.6Ref: TM-T8222
2mg34,00€5mg49,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg166,00€50mg259,00€100mg477,00€200mg692,00€500mg1.035,00€BMS-1166
CAS:BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.Fórmula:C36H33ClN2O7Pureza:99.22%Cor e Forma:SolidPeso molecular:641.11Ref: TM-T5697
1mg71,00€5mg146,00€1mL*10mM (DMSO)197,00€10mg213,00€25mg406,00€50mg602,00€100mg893,00€200mg1.198,00€Oroxin B
CAS:Oroxin B (Hypocretin-2) has antioxidant activity.Fórmula:C27H30O15Pureza:98.22% - 99.87%Cor e Forma:SolidPeso molecular:594.52Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Fórmula:C32H46O8Pureza:97.1% - 99.93%Cor e Forma:SolidPeso molecular:558.70Larotrectinib sulfate
CAS:Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).Fórmula:C21H22F2N6O2·H2O4SPureza:98.62% - 99.76%Cor e Forma:SolidPeso molecular:526.51Ref: TM-T6880
2mg37,00€5mg54,00€1mL*10mM (DMSO)63,00€10mg88,00€25mg124,00€50mg155,00€100mg259,00€500mg623,00€2'-OMe-Guanosine
CAS:2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Fórmula:C11H15N5O5Pureza:99.93%Cor e Forma:White SolidPeso molecular:297.27Choline
CAS:Choline is a ubiquitous water soluble nutrient, often associated with the B vitaminsFórmula:C5H15NO2Pureza:85% - ≥98%Cor e Forma:LiquidPeso molecular:121.18Eprinomectin
CAS:Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.Fórmula:C50H75NO14Pureza:97.84% - ≥95%Cor e Forma:SolidPeso molecular:914.13MPTP hydrochloride
CAS:MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Fórmula:C12H16ClNPureza:96.35% - >99.99%Cor e Forma:SolidPeso molecular:209.72Ref: TM-T4081
5mg34,00€1mL*10mM (DMSO)50,00€10mg52,00€25mg80,00€50mg131,00€100mg177,00€200mg281,00€500mg447,00€Cynaroside
CAS:Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.Fórmula:C21H20O11Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:448.38Ref: TM-T3376
1mg34,00€5mg71,00€1mL*10mM (DMSO)80,00€10mg98,00€25mg192,00€50mg339,00€100mg505,00€200mg717,00€CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Fórmula:C18H17F3N6O2Pureza:99.50%Cor e Forma:SolidPeso molecular:406.36Ref: TM-T9521
1mg60,00€5mg122,00€1mL*10mM (DMSO)142,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFórmula:C20H19N3O·CH4O3SPureza:99.58% - 99.88%Cor e Forma:SolidPeso molecular:413.49A-1155463
CAS:A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2, BCL-W and MCL-1.Fórmula:C35H32FN5O4S2Pureza:96.1% - 99%Cor e Forma:SolidPeso molecular:669.79RIPA-56
CAS:RIPA-56 is an inhibitor of RIP1Fórmula:C13H19NO2Pureza:99.53% - 99.93%Cor e Forma:SolidPeso molecular:221.3Ref: TM-T7795
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg89,00€50mg129,00€100mg202,00€200mg299,00€500mg504,00€Anagrelide hydrochloride
CAS:Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.
Fórmula:C10H7Cl2N3O·HClPureza:99.58%Cor e Forma:Off-White PowderPeso molecular:292.55A-1210477
CAS:A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).Fórmula:C46H55N7O7SPureza:99.17% - 99.37%Cor e Forma:SolidPeso molecular:850.04(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Fórmula:C13H14N2O3Pureza:98.41%Cor e Forma:SolidPeso molecular:246.26Ref: TM-T5379
1mg38,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg122,00€25mg198,00€50mg295,00€100mg424,00€200mg593,00€Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Fórmula:C10H16O8Pureza:99.2% - 99.92%Cor e Forma:SolidPeso molecular:264.23NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Fórmula:C24H35N7·3HClPureza:96.48% - 99.54%Cor e Forma:SolidPeso molecular:530.96Ref: TM-T6342
2mgA consultar5mg55,00€1mL*10mM (DMSO)64,00€10mg88,00€25mg145,00€50mg260,00€100mg380,00€CCT007093
CAS:CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Fórmula:C15H12OS2Pureza:98% - 99.88%Cor e Forma:SolidPeso molecular:272.39PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Fórmula:C16H19N5Pureza:99% - 99.88%Cor e Forma:Off-White To Grey SolidPeso molecular:281.36Ref: TM-T6196
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)89,00€10mg112,00€25mg190,00€50mg268,00€100mg421,00€500mg945,00€5-Geranoxy-7-methoxycoumarin
CAS:5-Geranoxy-7-methoxycoumarin shows antifungal activity.Fórmula:C20H24O4Pureza:98.94% - 99.99%Cor e Forma:SolidPeso molecular:328.4Ref: TM-TN3110
1mg99,00€5mg231,00€1mL*10mM (DMSO)244,00€10mg343,00€25mg575,00€50mg802,00€100mg1.108,00€NSC622608
CAS:NSC622608, a VISTA ligand, modulates T-cell tumor attacks as an immune checkpoint.Fórmula:C9H12BrN3OS2Pureza:98.48%Cor e Forma:SolidPeso molecular:322.24
