Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Thalidomide-NH-CH2-COOH
CAS:<p>Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a</p>Fórmula:C15H13N3O6Pureza:96.3800%Cor e Forma:SolidPeso molecular:331.28Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Fórmula:C6H6O7Cor e Forma:SolidPeso molecular:190.11Apocynin
CAS:<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Fórmula:C9H10O3Pureza:99.71% - 99.98%Cor e Forma:Yellowish To Brown PowderPeso molecular:166.17Eltrombopag Olamine
CAS:<p>Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin</p>Fórmula:C29H36N6O6Pureza:99.59% - 99.89%Cor e Forma:SolidPeso molecular:564.63ISRIB (trans-isomer)
CAS:<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Fórmula:C22H24Cl2N2O4Pureza:97.86% - 99.27%Cor e Forma:SolidPeso molecular:451.34Thalidomide 4-fluoride
CAS:<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Fórmula:C13H9FN2O4Pureza:99.12%Cor e Forma:SolidPeso molecular:276.22Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.</p>Fórmula:C21H27ClN4O6Pureza:97.33%Cor e Forma:SolidPeso molecular:466.915Periplocin
CAS:<p>Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.</p>Fórmula:C36H56O13Pureza:99.66% - 99.74%Cor e Forma:SolidPeso molecular:696.82TrxR1-IN-B19
CAS:<p>TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress</p>Fórmula:C21H22O5Pureza:98.6%Cor e Forma:SolidPeso molecular:354.4Thalidomide-O-amido-C3-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.</p>Fórmula:C20H21F3N4O8Pureza:98.47%Cor e Forma:SolidPeso molecular:502.4Thalidomide-O-COOH
CAS:<p>Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.</p>Fórmula:C15H12N2O7Pureza:98% - 98.29%Cor e Forma:SolidPeso molecular:332.27Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Fórmula:C13H10N2O5Pureza:99.59%Cor e Forma:SolidPeso molecular:274.23Thalidomide-NH-C4-NH-Boc
CAS:<p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>Fórmula:C22H28N4O6Pureza:98.87%Cor e Forma:SolidPeso molecular:444.48Methoxyamine HCl
CAS:<p>Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.</p>Fórmula:CH6ClNOPureza:≥98%Cor e Forma:SolidPeso molecular:83.51Alogliptin Benzoate
CAS:<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Fórmula:C25H27N5O4Pureza:99.94% - >99.99%Cor e Forma:White PowderPeso molecular:461.51OICR-9429
CAS:<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Fórmula:C29H32F3N5O3Pureza:97.07% - 99.93%Cor e Forma:SolidPeso molecular:555.59Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS:<p>Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.</p>Fórmula:C25H31F3N4O11Pureza:99.82%Cor e Forma:SolidPeso molecular:620.54Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Fórmula:C19H26O7Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:366.41PK11000
CAS:<p>PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.</p>Fórmula:C6H5ClN2O4SPureza:99.70%Cor e Forma:SolidPeso molecular:236.63Abacavir monosulfate
CAS:<p>Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.</p>Fórmula:C14H20N6O5SCor e Forma:SolidPeso molecular:384.41Benidipine hydrochloride
CAS:<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Fórmula:C28H32ClN3O6Pureza:99.80%Cor e Forma:SolidPeso molecular:542.03Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Fórmula:C23H27F3N4O10Pureza:95.74% - 99%Cor e Forma:SolidPeso molecular:576.48MS7972
CAS:<p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>Fórmula:C14H13NO2Pureza:99.78%Cor e Forma:SolidPeso molecular:227.26KX2-361
CAS:<p>KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma</p>Fórmula:C24H24FN3O2Pureza:99.64% - 99.68%Cor e Forma:SolidPeso molecular:405.46Fipronil
CAS:<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:Solid PowderPeso molecular:437.15Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Cor e Forma:SolidPeso molecular:612.74Crebanine
CAS:<p>Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.</p>Fórmula:C20H21NO4Pureza:99.17% - 99.77%Cor e Forma:SolidPeso molecular:339.39Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.66Mitochonic acid 5
CAS:<p>MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.</p>Fórmula:C18H13F2NO3Pureza:98.85%Cor e Forma:SolidPeso molecular:329.3Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Fórmula:C44H51ClF3N5O5S3Pureza:99.87%Cor e Forma:SolidPeso molecular:918.55Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Fórmula:C10H7Cl2N3O·HClPureza:99.58%Cor e Forma:Off-White PowderPeso molecular:292.55Lercanidipine hydrochloride
CAS:<p>Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.</p>Fórmula:C36H41N3O6·HClPureza:99.86% - 99.91%Cor e Forma:Pale-Yellow PowderPeso molecular:648.194-Oxofenretinide
CAS:<p>4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.</p>Fórmula:C26H31NO3Pureza:96.89%Cor e Forma:SolidPeso molecular:405.53Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C19H32N2O4Pureza:99.26%Cor e Forma:CoaPeso molecular:352.471-(1-Naphthyl) piperazine hydrochloride
CAS:<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Fórmula:C14H17ClN2Pureza:98.27%Cor e Forma:SolidPeso molecular:248.75Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Fórmula:C32H43NO4Pureza:97.81% - 99.09%Cor e Forma:SolidPeso molecular:505.692-Bromohexadecanoic acid
CAS:<p>2-Bromohexadecanoic acid (2-BP) is a PPARδ agonist, and a palmitoylation inhibitor, inhibiting DHHC-mediated palmitoylation. Cost-effective and quality-assured.</p>Fórmula:C16H31BrO2Pureza:97% - 98.3%Cor e Forma:White Crystalline PowderPeso molecular:335.32Vildagliptin dihydrate
CAS:<p>Vildagliptin dihydrate: potent, selective DPP-IV inhibitor with 3.5 nM IC50, high oral bioavailability, effective against hyperglycemia.</p>Fórmula:C17H29N3O4Cor e Forma:SolidPeso molecular:339.436Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Fórmula:C19H20O5Pureza:97.22% - 99.84%Cor e Forma:SolidPeso molecular:328.36Deguelin
CAS:<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Fórmula:C23H22O6Pureza:96.39% - 99.29%Cor e Forma:SolidPeso molecular:394.42JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Fórmula:C19H17ClN4O2SPureza:99.14% - 99.9%Cor e Forma:SolidPeso molecular:400.88Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:487.53Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Fórmula:C16H14F2N3NaO4SPureza:96.92% - 99.81%Cor e Forma:White To Off-White SolidPeso molecular:405.35Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Fórmula:C10H8O10S3Pureza:99.85%Cor e Forma:SolidPeso molecular:384.36Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-PEG-C2-NH2 HCl is a cereblon ligand-linker for PROTAC synthesis.</p>Fórmula:C19H23ClN4O7Pureza:95%Cor e Forma:SolidPeso molecular:454.862Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Fórmula:C16H14F3IN2O4Pureza:99.11% - 99.63%Cor e Forma:White PowderPeso molecular:482.19BTR-1
CAS:<p>5-Benzylidene-3-ethyl rhodanine(BTR-1 (5-Benzylidene-3-ethyl rhodanine)) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.</p>Fórmula:C12H11NOS2Pureza:98%Cor e Forma:SolidPeso molecular:249.35Picrocrocin
CAS:<p>Picrocrocin is a natural product</p>Fórmula:C16H26O7Pureza:98.4%Cor e Forma:SolidPeso molecular:330.374-Methylbenzylidene camphor
CAS:<p>4-Methylbenzylidene camphor: UVB blocker in sunscreens, cosmetics; exhibits estrogenic activity.</p>Fórmula:C18H22OPureza:99.92%Cor e Forma:White SolidPeso molecular:254.37Necroptosis-IN-1
CAS:<p>Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.</p>Fórmula:C12H10ClN3O2Pureza:99.73% - 99.8%Cor e Forma:SolidPeso molecular:263.68
