Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFórmula:C25H35N7O9S4Pureza:99.63%Cor e Forma:SolidPeso molecular:705.85Lexatumumab
CAS:Lexatumumab (GHS-ETR2), a human antibody, targets TRAILR2 for anticancer effects and apoptosis in mesothelioma.
Pureza:> 95%Cor e Forma:LiquidPeso molecular:143.48 kDaConatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145.44 kDaCDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Fórmula:C33H45F3N2O3Pureza:95.61% - 99.59%Cor e Forma:SolidPeso molecular:574.72Ref: TM-T13604
1mg66,00€2mg96,00€5mg144,00€10mg241,00€25mg485,00€50mg700,00€100mg982,00€500mg1.953,00€1mL*10mM (DMSO)177,00€Risedronic Acid
CAS:Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.Fórmula:C7H11NO7P2Pureza:99.85% - 99.87%Cor e Forma:White Crystalline PowderPeso molecular:283.11Moroxydine hydrochloride
CAS:Moroxydine hydrochloride (ABOB hydrochloride) is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines.
Fórmula:C6H13N5O·HClPureza:99.15%Cor e Forma:White Crystalline PowderPeso molecular:207.66Prucalopride
CAS:Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.Fórmula:C18H26ClN3O3Pureza:99.99% - >99.99%Cor e Forma:SolidPeso molecular:367.87Primidone
CAS:Primidone (NCI-C56360) is a potent anticonvulsant agent.Fórmula:C12H14N2O2Pureza:99.91%Cor e Forma:Crystals (Ntp 1992)Peso molecular:218.25Ibandronate sodium
CAS:Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.Fórmula:C9H22NNaO7P2Pureza:98.13%Cor e Forma:SolidPeso molecular:341.21Probucol
CAS:Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.Fórmula:C31H48O2S2Pureza:99.89% - 99.95%Cor e Forma:SolidPeso molecular:516.84Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Cor e Forma:SolidPeso molecular:288.82Tetraethylenepentamine Pentahydrochloride
CAS:Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.Fórmula:C8H23N5·5HClPureza:≥95%Cor e Forma:SolidPeso molecular:371.61Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Fórmula:C11H16O2Pureza:99.54% - 99.63%Cor e Forma:White Solid WaxyPeso molecular:180.25BLU-222
CAS:BLU-222 is a potent, selective and orally active CDK2 inhibitor. BLU-222 shows robust antitumor activity.
Fórmula:C15H17F2N7O2Pureza:99.17% - 99.92%Cor e Forma:SoildPeso molecular:365.34Sodium 4-phenylbutyrate
CAS:Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.Fórmula:C10H11NaO2Pureza:99.02% - >99.99%Cor e Forma:SolidPeso molecular:186.18RMC-7977
CAS:RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.Fórmula:C47H60N8O6SPureza:97.11% - 99.86%Cor e Forma:SolidPeso molecular:865.09Ref: TM-T81263
1mg231,00€5mg580,00€10mg888,00€25mg1.378,00€50mg1.783,00€100mg2.512,00€1mL*10mM (DMSO)888,00€Serplulimab
CAS:Serplulimab (HLX 10) is a humanized monoclonal anti-antibody to PD-1.
Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.06 kDaGCN2iB
CAS:GCN2iB is an ATP-competitive inhibitor of serine/threonine protein kinase, stress-responsive kinase (GCN2).Cost-effective and quality-assured.Fórmula:C18H12ClF2N5O3SPureza:99.08%Cor e Forma:SolidPeso molecular:451.83Ref: TM-T11375
1mg80,00€5mg166,00€10mg259,00€25mg518,00€50mg742,00€100mg1.018,00€1mL*10mM (DMSO)177,00€Levonorgestrel
CAS:Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device.Fórmula:C21H28O2Pureza:99.42% - 99.44%Cor e Forma:Crystals From Methanol SolidPeso molecular:312.45Lonidamine
CAS:Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-Fórmula:C15H10Cl2N2O2Pureza:97.90%Cor e Forma:White To Light Yellow CrystalPeso molecular:321.16Ref: TM-T0239
1g500,00€2mg37,00€5mg50,00€10mg60,00€25mg78,00€50mg109,00€100mg141,00€500mg335,00€1mL*10mM (DMSO)52,00€Dequalinium chloride
CAS:Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.
Fórmula:C30H40Cl2N4Pureza:99.79% - 99.9%Cor e Forma:SolidPeso molecular:527.59Tolperisone hydrochloride
CAS:Tolperisone hydrochloride (Muscalm) is a muscle relaxant for treating muscle tone disorders from neurological diseases.Fórmula:C16H24ClNOPureza:99.51%Cor e Forma:White SolidPeso molecular:281.82SLU-PP-1072
CAS:SLU-PP-1072: inverse agonist for ERRα/γ, disrupts PCa metabolism, induces apoptosis, studies prostate cancer.Fórmula:C18H12N2O3SPureza:97.66%Cor e Forma:SoildPeso molecular:336.36Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Fórmula:C10H8N2O2S2ZnPureza:99.09% - 99.70%Cor e Forma:Off-White To Tan PowderPeso molecular:317.71Human RANKL(Receptor Activator of Nuclear factor-kB Ligand) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RANKL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RANKL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human RANKL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human RANKL in the samples is then determined by comparing the OD of the samples to the standard curve.Cor e Forma:Colourless TransparentliquidSemapimod tetrahydrochloride
CAS:Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor.Fórmula:C34H56Cl4N18O2Pureza:97.21% - 99.8%Cor e Forma:SolidPeso molecular:890.74GPI-1046
CAS:GPI-1046: immunophilin ligand, no antibiotic effect, reduces ethanol intake by boosting GLT1 in PFC and NAc-core.
Fórmula:C20H28N2O4Pureza:99.69%Cor e Forma:SolidPeso molecular:360.45Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Fórmula:C8H9ClN4Pureza:99.85% - 99.86%Cor e Forma:Yellow Crystals White Crystalline SolidPeso molecular:196.64Ref: IN-DA006YB9
1gA consultar1mg50,00€5mg52,00€10mg68,00€25mg129,00€50mg150,00€100mg163,00€250mg555,00€Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Fórmula:C21H27NO3Pureza:99.02%Cor e Forma:SolidPeso molecular:341.44ROS-generating agent 1
CAS:Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR.
Fórmula:C21H15F6NOPureza:99.67%Cor e Forma:SoildPeso molecular:411.34Cemiplimab
CAS:Cemiplimab, a human antibody, blocks PD-1 to inhibit T-cell suppression in metastatic and skin cancer studies.
Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.2%Cor e Forma:LiquidPeso molecular:143.81 kDa(E)-Methyl 4-coumarate
CAS:(E)-Methyl 4-coumarate (OMpCA) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of methyl 3-phenylprop-2-enoate.Fórmula:C10H10O3Pureza:99.68% - 99.97%Cor e Forma:White Crystal PowderPeso molecular:178.18Ecabet Sodium
CAS:Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.Fórmula:C20H27NaO5SPureza:99.90%Cor e Forma:SolidPeso molecular:402.48(R)-HTS-3
CAS:(R)-HTS-3 is a LPCAT3 inhibitor that remodels the polyunsaturated phospholipid content of human cells and prevents iron death.
Fórmula:C17H18F2N2OPureza:98.89%Cor e Forma:SoildPeso molecular:304.33ACHP
CAS:ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β.Fórmula:C21H24N4O2Pureza:98.77%Cor e Forma:SolidPeso molecular:364.44Ref: TM-T22021
1mg50,00€5mg101,00€10mg150,00€25mg241,00€50mg353,00€100mg602,00€200mg982,00€500mg1.963,00€Human sHLA-G(soluble human leucocyte antigen G) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human sHLA-G. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human sHLA-G. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human sHLA-G, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human sHLA-G in the samples is then determined by comparing the OD of the samples to the standard curve.Vitamin K4
CAS:Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4.Fórmula:C15H14O4Pureza:99.84%Cor e Forma:White Crystalline PowderPeso molecular:258.27Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56Ref: TM-T14381
1mg70,00€5mg152,00€10mg236,00€25mg432,00€50mg647,00€100mg964,00€1mL*10mM (DMSO)166,00€AP20187
CAS:AP20187: Cell-permeable ligand dimerizing FKBP fusion proteins for signaling and gene expression control.Fórmula:C82H107N5O20Pureza:99.05% - 99.80%Cor e Forma:SolidPeso molecular:1482.75Gboxin
CAS:Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.Fórmula:C22H33ClN2O2Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:392.96Ref: TM-T15373
1mg42,00€2mg55,00€5mg88,00€10mg126,00€25mg245,00€50mg385,00€100mg612,00€200mg850,00€1mL*10mM (DMSO)87,00€Lilotomab
CAS:Lilotomab (HH1), a murine anti-CD37 monoclonal antibody, demonstrates anti-tumor activity by reducing clonogenic survival [1].
Pureza:97.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 97.4% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:LiquidSodium butanoate
CAS:Sodium butanoate (Sodium Butyrate) is the sodium salt of butyrate with potential antineoplastic activity.
Fórmula:C4H7NaO2Pureza:98.02% - 99.79%Cor e Forma:White PowderPeso molecular:110.09Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Cor e Forma:Fine Off-White Crystalline PowderPeso molecular:243.22Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Cor e Forma:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Vorinostat
CAS:Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.Fórmula:C14H20N2O3Pureza:99.47% - 99.65%Cor e Forma:White Crystalline SolidPeso molecular:264.32HPPH
CAS:HPPH (Photochlor) (Photochlor) is a second-generation photosensitizer. It is used as photodynamic therapy (PDT) agent.Fórmula:C39H48N4O4Pureza:99.72%Cor e Forma:Black Solid PowderPeso molecular:636.82Ref: TM-T15501
1mg63,00€2mg92,00€5mg137,00€10mg236,00€25mg409,00€50mgA consultar1mL*10mM (DMSO)177,00€Lornoxicam
CAS:Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, andFórmula:C13H10ClN3O4S2Pureza:98.74% - 99.28%Cor e Forma:Crystalline SolidPeso molecular:371.82Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Fórmula:C27H30O7Pureza:95.84% - 99.4%Cor e Forma:SolidPeso molecular:466.52Ref: TM-T16324
1mg67,00€5mg167,00€10mg289,00€25mg595,00€50mg820,00€100mg1.108,00€200mg1.440,00€1mL*10mM (DMSO)180,00€
