Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Ifabotuzumab
CAS:<p>Ifabotuzumab (KB-004) is an antibody targeting EphA3+ cells, significantly reducing CCR10+ cells and improving pulmonary fibrosis in humanized NSG mice.</p>Pureza:>95%Cor e Forma:LiquidIsatuximab
CAS:<p>Isatuximab targets CD38 in blood cancers, with high expression in multiple myeloma, inducing apoptosis and impairing cellular functions.</p>Pureza:SDS-PAGE:97.4%;SEC-HPLC:98.4%Cor e Forma:LiquidPeso molecular:145.21 kDaTrifluridine
CAS:<p>Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.</p>Fórmula:C10H11F3N2O5Pureza:99.39% - 99.82%Cor e Forma:White Crystalline PowderPeso molecular:296.2S-allyl-L-cysteine
CAS:<p>S-allyl-L-cysteine (S-Allylcysteine), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.</p>Fórmula:C6H11NO2SPureza:97.84% - 99.87%Cor e Forma:SolidPeso molecular:161.22Theophylline monohydrate
CAS:<p>Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium</p>Fórmula:C7H8N4O2·H2OPureza:99.78%Cor e Forma:SolidPeso molecular:198.18FSEN1
CAS:<p>FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.</p>Fórmula:C22H22BrN5OSPureza:98.56% - 99.54%Cor e Forma:SolidPeso molecular:484.41(E)-Cardamonin
CAS:<p>(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera.</p>Fórmula:C16H14O4Pureza:99.07% - 99.84%Cor e Forma:SolidPeso molecular:270.28Dacarbazine
CAS:<p>Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.</p>Fórmula:C6H10N6OPureza:99.78% - 99.87%Cor e Forma:Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)Peso molecular:182.18Ulocuplumab
CAS:<p>Ulocuplumab is a human anti-CXCR4 IgG4 antibody tackling AML, NHL, and multiple myeloma; induces CLL apoptosis.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:96.2%Cor e Forma:LiquidPeso molecular:146.23 kDaTea polyphenol
CAS:<p>Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.</p>Fórmula:C17H19N3OPureza:98%Cor e Forma:Yelloish Green Free Flowing PowderPeso molecular:281.36Ketoprofen
CAS:<p>Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects.</p>Fórmula:C16H14O3Pureza:99.67% - 99.97%Cor e Forma:SolidPeso molecular:254.28Conatumumab
CAS:<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145 kDa (average)UCB-9260
CAS:<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Fórmula:C26H25N5OPureza:98.39% - 99.24%Cor e Forma:SolidPeso molecular:423.51iFSP1
CAS:<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Fórmula:C20H13N5Pureza:98.74% - 99.74%Cor e Forma:SolidPeso molecular:323.35Lonidamine
CAS:<p>Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-</p>Fórmula:C15H10Cl2N2O2Pureza:97.90%Cor e Forma:White To Light Yellow CrystalPeso molecular:321.16Lidocaine Hydrochloride hydrate
CAS:<p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Cor e Forma:SolidPeso molecular:288.82Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Fórmula:C8H12ClNO3Pureza:98.34% - 99.85%Cor e Forma:Physical Description Beige Solid (Ntp 1992)Peso molecular:205.64Sunitinib
CAS:<p>Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).</p>Fórmula:C22H27FN4O2Pureza:98% - 99.67%Cor e Forma:Yellow SolidPeso molecular:398.47Lornoxicam
CAS:<p>Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and</p>Fórmula:C13H10ClN3O4S2Pureza:98.74% - 99.28%Cor e Forma:Crystalline SolidPeso molecular:371.82Dabuzalgron
CAS:<p>Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence.</p>Fórmula:C12H16ClN3O3SPureza:98.35%Cor e Forma:SolidPeso molecular:317.79Cytarabine
CAS:<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Cor e Forma:Fine Off-White Crystalline PowderPeso molecular:243.22Vorinostat
CAS:<p>Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.</p>Fórmula:C14H20N2O3Pureza:99.47% - 99.65%Cor e Forma:White Crystalline SolidPeso molecular:264.32Budigalimab
CAS:<p>Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.</p>Pureza:97% (SDS-PAGE); 98.8% (SEC-HPLC) - 97% (SDS-PAGE); 98.8% (SEC-HPLC)Cor e Forma:LiquidCyclamic acid
CAS:<p>Cyclamic acid, a synthetic sweetener (NSC-220327), often used as Na/Ca cyclamate. Banned in USA over disputed cancer risk.</p>Fórmula:C6H13NO3SPureza:98.42%Cor e Forma:White CrystalsPeso molecular:179.24Linagliptin
CAS:<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Fórmula:C25H28N8O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:472.54Benazepril hydrochloride
CAS:<p>Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension.</p>Fórmula:C24H29ClN2O5Pureza:99.68% - ≥95%Cor e Forma:Crystalline SolidPeso molecular:460.95Cemiplimab
CAS:<p>Cemiplimab, a human antibody, blocks PD-1 to inhibit T-cell suppression in metastatic and skin cancer studies.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.2%Cor e Forma:LiquidPeso molecular:143.81 kDaChlorhexidine
CAS:<p>Chlorhexidine is a biguanide antiseptic targeting bacteria, damaging cell membranes and causing cell death, more effective against gram-positive types.</p>Fórmula:C22H30Cl2N10Pureza:98% - 99.85%Cor e Forma:Crystals From Methanol SolidPeso molecular:505.45Quinacrine dihydrochloride
CAS:<p>Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic</p>Fórmula:C23H30CLN3O·2HClPureza:98.24% - 99.80%Cor e Forma:Yellow Crystals Or PowderPeso molecular:472.88Nifuratel
CAS:<p>Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.</p>Fórmula:C10H11N3O5SPureza:99.76% - 99.87%Cor e Forma:Fresh Yellow Crystalline Or Yellow PowderPeso molecular:285.28Docetaxel
CAS:<p>Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM).</p>Fórmula:C43H53NO14Pureza:98.6% - 99.29%Cor e Forma:Off-White CrystPeso molecular:807.88Acesulfame Potassium
CAS:<p>Acesulfame potassium is a non-nutritive sweetener.</p>Fórmula:C4H4KNO4SPureza:99.65%Cor e Forma:White Solid CrystallinePeso molecular:201.24JTE-013
CAS:<p>JTE-013 is an effective and specific antagonist of S1P2.</p>Fórmula:C17H19Cl2N7OPureza:97.69%Cor e Forma:SolidPeso molecular:408.29Milnacipran hydrochloride
CAS:<p>Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders.</p>Fórmula:C15H23ClN2OPureza:99.7% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:282.81Prucalopride
CAS:<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.</p>Fórmula:C18H26ClN3O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:367.87Tizanidine hydrochloride
CAS:<p>Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.</p>Fórmula:C9H9Cl2N5SPureza:99.96%Cor e Forma:Solid WhitePeso molecular:290.17Diethylstilbestrol
CAS:<p>Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.</p>Fórmula:C18H20O2Pureza:97.77% - 98.78%Cor e Forma:White Crystalline Powder Physical Description Odorless Tasteless White Crystalline Powder (Ntp 1992)Peso molecular:268.35Ac-FLTD-CMK
CAS:<p>Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.</p>Fórmula:C26H37ClN4O8Pureza:95.17%Cor e Forma:SolidPeso molecular:569.05Probucol
CAS:<p>Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.</p>Fórmula:C31H48O2S2Pureza:99.89% - 99.95%Cor e Forma:SolidPeso molecular:516.84Diclofenac diethylamine
CAS:<p>Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).</p>Fórmula:C18H22Cl2N2O2Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:369.29Bithionol
CAS:<p>Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to</p>Fórmula:C12H6Cl4O2SPureza:99.04%Cor e Forma:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Peso molecular:356.05Butylhydroxyanisole
CAS:<p>BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.</p>Fórmula:C11H16O2Pureza:99.54% - 99.63%Cor e Forma:White Solid WaxyPeso molecular:180.25Benzydamine hydrochloride
CAS:<p>Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.</p>Fórmula:C19H23N3O·HClPureza:99.01%Cor e Forma:The White Crystalline PowderPeso molecular:345.87Olsalazine disodium
CAS:<p>Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.</p>Fórmula:C14H8N2Na2O6Pureza:99.47% - 99.52%Cor e Forma:Yellow Crystalline PowderPeso molecular:346.2Penfluridol
CAS:<p>Penfluridol (TLP-607) is a highly potent antipsychotic.</p>Fórmula:C28H27ClF5NOPureza:98.9% - 99.87%Cor e Forma:Off-White To White Crystalline PowderPeso molecular:523.97Chlorquinaldol
CAS:<p>Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is an antimicrobial agent with potential for study of topical skin conditions and vaginal infections.</p>Fórmula:C10H7Cl2NOPureza:98.22% - 99.77%Cor e Forma:Yellow To Brown Crystalline PowderPeso molecular:228.07Ascorbyl palmitate
CAS:<p>Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C.</p>Fórmula:C22H38O7Pureza:99.52%Cor e Forma:White Or Yellowish White Powder White Or Yellowish-White Powder With A Citrus-Like OdourPeso molecular:414.53Minocycline hydrochloride
CAS:<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Cor e Forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94Mevastatin
CAS:<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Fórmula:C23H34O5Pureza:99.12%Cor e Forma:White-Yellowish To Yellow Powder Solid PowderPeso molecular:390.51Certolizumab pegol
CAS:<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Pureza:95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:Liquid
