Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6222 produtos de "Apoptose"
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L-Theanine
CAS:L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.Fórmula:C7H14N2O3Pureza:99.31% - 99.38%Cor e Forma:White Crystals From Ethanol + Water White Crystalline SolidPeso molecular:174.20Glaucocalyxin A
CAS:Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.Fórmula:C20H28O4Pureza:99.55% - 99.80%Cor e Forma:SolidPeso molecular:332.43Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Fórmula:C18H15N5OPureza:97.03%Cor e Forma:SolidPeso molecular:317.34Pyroxamide
CAS:Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
Fórmula:C13H19N3O3Pureza:98.46%Cor e Forma:SolidPeso molecular:265.31Pinoresinol
CAS:Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injuryFórmula:C20H22O6Pureza:98.67%Cor e Forma:SolidPeso molecular:358.39Ref: TM-TN2080
1mg54,00€5mg114,00€1mL*10mM (DMSO)128,00€10mg177,00€25mg295,00€50mg442,00€100mg620,00€1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Fórmula:C21H13ClF3N3O2Pureza:99.41%Cor e Forma:SolidPeso molecular:431.8Ref: TM-T22424
1mg42,00€2mg55,00€5mg88,00€1mL*10mM (DMSO)99,00€10mg127,00€25mg264,00€50mg432,00€100mg622,00€200mg873,00€2-Deoxy-D-glucose
CAS:2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.Fórmula:C6H12O5Pureza:98% - ≥98%Cor e Forma:White PowderPeso molecular:164.16BX-912
CAS:BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.Fórmula:C20H23BrN8OPureza:98.29% - 99.34%Cor e Forma:SolidPeso molecular:471.35Ref: TM-T1837
1mg50,00€2mg71,00€5mg85,00€1mL*10mM (DMSO)88,00€10mg137,00€25mg281,00€50mg470,00€100mg632,00€Supinoxin
CAS:Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).Fórmula:C22H24FN5O4Pureza:99.83% - 99.95%Cor e Forma:SolidPeso molecular:441.46Ref: TM-T16961
1mg107,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64CCT128930 hydrochloride
CAS:CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.Fórmula:C18H21Cl2N5Pureza:98.55%Cor e Forma:SolidPeso molecular:378.3Ref: TM-T6303L
1mg49,00€5mg92,00€1mL*10mM (DMSO)104,00€10mg148,00€25mg240,00€50mg359,00€100mg523,00€200mg772,00€Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Fórmula:C9H18N2O3PtPureza:98.00%Cor e Forma:SolidPeso molecular:397.33L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Fórmula:NAPureza:97%Cor e Forma:SolidPeso molecular:N/ASGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Fórmula:C20H22F3N5OPureza:99.3% - >99.99%Cor e Forma:SolidPeso molecular:405.42Ref: TM-T3078
1mgA consultar5mg90,00€1mL*10mM (DMSO)94,00€10mg145,00€25mg281,00€50mg409,00€100mg528,00€Elesclomol
CAS:Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier.Fórmula:C19H20N4O2S2Pureza:97.17% - 99.51%Cor e Forma:SolidPeso molecular:400.52Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Fórmula:C10H19N2O5PPureza:99.99% - ≥95%Cor e Forma:SolidPeso molecular:278.24Ref: TM-T6641
1mg34,00€5mg67,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg152,00€50mg230,00€100mg363,00€200mg528,00€HO-3867
CAS:HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.Fórmula:C28H30F2N2O2Pureza:91.18% - 99.21%Cor e Forma:SolidPeso molecular:464.55LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69kauran-16,17-diol
CAS:Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7Fórmula:C20H34O2Pureza:99.93%Cor e Forma:SolidPeso molecular:306.48Ref: TM-T4951
1mg64,00€1mL*10mM (DMSO)163,00€5mg170,00€10mg245,00€25mg371,00€50mg504,00€100mg675,00€200mg900,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47NSC 95397
CAS:NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).Fórmula:C14H14O4S2Pureza:98.66%Cor e Forma:SolidPeso molecular:310.39Diffractaic Acid
CAS:Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.Fórmula:C20H22O7Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:374.38SKI II
CAS:SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.Fórmula:C15H11ClN2OSPureza:99.34% - 99.93%Cor e Forma:SolidPeso molecular:302.78[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Fórmula:C17H26O4Pureza:98% - 99.66%Cor e Forma:Light Yellow OilinessPeso molecular:294.39STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:98.66%Cor e Forma:SolidPeso molecular:461.53GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Cor e Forma:SolidPeso molecular:333.36GMB-475
CAS:GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Cor e Forma:SolidPeso molecular:861.93Ref: TM-T8488
1mg50,00€2mg66,00€5mg99,00€1mL*10mM (DMSO)152,00€10mg160,00€25mg281,00€50mg416,00€100mg600,00€200mg835,00€2-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Fórmula:C15H12O2Pureza:99.6%Cor e Forma:SolidPeso molecular:224.25Pracinostat
CAS:Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oralFórmula:C20H30N4O2Pureza:99.15% - 99.67%Cor e Forma:SolidPeso molecular:358.48Ref: TM-T1890
1mg48,00€2mg64,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg152,00€25mg268,00€50mg401,00€100mg592,00€200mg835,00€Phellamurin
CAS:Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.Fórmula:C26H30O11Pureza:97.91%Cor e Forma:SolidPeso molecular:518.51Ref: TM-TN4761
1mg155,00€5mg304,00€1mL*10mM (DMSO)389,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€Astragalin
CAS:Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.Fórmula:C21H20O11Pureza:98.8% - ≥95%Cor e Forma:SolidPeso molecular:448.38Ref: TM-T6S1101
1mg34,00€5mg62,00€1mL*10mM (DMSO)73,00€10mg86,00€25mg126,00€50mg178,00€100mg263,00€500mg645,00€Dinaciclib
CAS:Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).Fórmula:C21H28N6O2Pureza:98.21% - 99.75%Cor e Forma:SolidPeso molecular:396.49Etidronic acid
CAS:Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.Fórmula:C2H8O7P2Pureza:99.93% - ≥95%Cor e Forma:Liquid SyrupPeso molecular:206.03Nafamostat mesylate
CAS:Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitisFórmula:C19H17N5O2·2CH4O3SPureza:97.36% - 99.76%Cor e Forma:Tan To Pale Orange SolidPeso molecular:539.58KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Fórmula:C20H20N4OPureza:98.43% - 99.69%Cor e Forma:SolidPeso molecular:332.4WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Fórmula:C20H20N2O3SPureza:99.77%Cor e Forma:SolidPeso molecular:368.45Amentoflavone
CAS:Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Fórmula:C30H18O10Pureza:98.21% - 99.22%Cor e Forma:Odourless Whitish SolidPeso molecular:538.46Ref: TM-T3417
2mg34,00€5mg50,00€1mL*10mM (DMSO)59,00€10mg80,00€25mg126,00€50mg215,00€100mg349,00€200mg512,00€BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting
Fórmula:C20H18N6O3Pureza:98.72%Cor e Forma:SolidPeso molecular:390.4Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 99.99%Cor e Forma:SolidPeso molecular:510.61Ref: TM-T9497
5mg57,00€1mL*10mM (DMSO)66,00€10mg82,00€25mg111,00€50mg137,00€100mg205,00€200mg309,00€500mg515,00€Sacubitril/Valsartan
CAS:Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for treatment of hypertension and heart failure.Fórmula:C48H55N6O8Na3·5H2OPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:957.99Ref: TM-T2318
2mg43,00€5mg63,00€10mg88,00€1mL*10mM (DMSO)93,00€25mg117,00€50mg147,00€100mg178,00€500mg442,00€SKI-178
CAS:SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM.Fórmula:C21H22N4O4Pureza:97.09%Cor e Forma:SolidPeso molecular:394.42Ref: TM-T9014
2mg46,00€5mg69,00€1mL*10mM (DMSO)75,00€10mg108,00€25mg203,00€50mg326,00€100mg492,00€500mg1.054,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:718.08Etretinate
CAS:Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.Fórmula:C23H30O3Pureza:97.89%Cor e Forma:Crystals Crystalline SolidPeso molecular:354.48Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Cor e Forma:SolidPeso molecular:443.26Psoralen
CAS:Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
Fórmula:C11H6O3Pureza:99.3% - 99.87%Cor e Forma:Crystals From Ether Crystalline SolidPeso molecular:186.16Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63Isolongifolene
CAS:Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, andFórmula:C15H24Pureza:90.13% - 99.46%Cor e Forma:Colorless Or Light Yellow LiquidPeso molecular:204.35ERK1/2 inhibitor 2
CAS:ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.Fórmula:C29H31ClFN5O5Pureza:98.99%Cor e Forma:SolidPeso molecular:584.04
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