Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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5-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Fórmula:C5H10ClNO3Pureza:98% - 99.97%Cor e Forma:White To Pale Yellow Crystals OrPeso molecular:167.59PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Fórmula:C16H14BrN5O4S·HClPureza:97.82%Cor e Forma:SolidPeso molecular:488.74Tauroursodeoxycholate sodium
CAS:<p>Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.</p>Fórmula:C26H44NNaO6SPureza:97.90%Cor e Forma:SolidPeso molecular:521.69Y-320
CAS:<p>Y-320 is a new phenylpyrazoleanilide immunomodulator.</p>Fórmula:C27H29ClN6O2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:505.01Tetramethylcurcumin
CAS:<p>Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also</p>Fórmula:C25H28O6Pureza:97.69% - 99.94%Cor e Forma:SolidPeso molecular:424.49Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Fórmula:C7H7NO2Pureza:97.585% - 99.49%Cor e Forma:Prisms Aqueous From Alcohol + Water SolidPeso molecular:137.14Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Cor e Forma:SolidPeso molecular:1031.18INH6
CAS:<p>INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.</p>Fórmula:C19H18N2OSPureza:98.81%Cor e Forma:SolidPeso molecular:322.42Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Fórmula:C15H12O5Pureza:98.76% - >99.99%Cor e Forma:SolidPeso molecular:272.25Tebufenozide
CAS:<p>Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.</p>Fórmula:C22H28N2O2Pureza:98%Cor e Forma:SolidPeso molecular:352.47Sincalide
CAS:<p>Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.</p>Fórmula:C49H62N10O16S3Pureza:98.32%Cor e Forma:SolidPeso molecular:1143.27INCB-057643
CAS:<p>INCB057643 is a potent, selective and orally bioavailable BET inhibitor.</p>Fórmula:C20H21N3O5SPureza:99.5%Cor e Forma:SolidPeso molecular:415.46JIB-04
CAS:<p>JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.</p>Fórmula:C17H13ClN4Pureza:98.02% - 98.87%Cor e Forma:SolidPeso molecular:308.76Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Fórmula:C45H72O16Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:869.04Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Fórmula:C12H14O2Pureza:96.03% - 98.14%Cor e Forma:Yellow Brown PowderPeso molecular:190.24Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H20N4O3Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:376.41Poncirin
CAS:<p>Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.</p>Fórmula:C28H34O14Pureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:594.56Vandetanib hydrochloride
CAS:<p>Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).</p>Fórmula:C22H25BrClFN4O2Cor e Forma:SolidPeso molecular:511.81Zoledronic acid disodium tetrahydrate
CAS:<p>Zoledronic Acid, a potent bisphosphonate, inhibits osteoclasts and has anti-cancer effects.</p>Fórmula:C5H16N2Na2O11P2Cor e Forma:SolidPeso molecular:388.113Cucurbitacin IIb
CAS:<p>Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.</p>Fórmula:C30H48O7Pureza:98.66% - >99.99%Cor e Forma:SolidPeso molecular:520.7Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Fórmula:C24H30N6O2Pureza:98.87%Cor e Forma:SolidPeso molecular:434.53β-mangostin
CAS:<p>β-Mangostin: a xanthone in Cratoxylum arborescens, fights bacteria, malaria, tuberculosis (MIC 6.25μg/mL), and cancer.</p>Fórmula:C25H28O6Pureza:98.01% - 99.69%Cor e Forma:Faintly Yellow PowderPeso molecular:424.49Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:608.72D-Pantothenic acid sodium
CAS:<p>D-Pantothenic acid sodium, a sodium salt of D-pantothenate, is a vital B5 derivative, aiding fat, carb, and amino acid oxidation.</p>Fórmula:C9H16NNaO5Pureza:97.98%Cor e Forma:White PowderPeso molecular:241.22Sophoridine
CAS:Sophoridine, a natural Chinese anticancer drug, has a potent derivative 6b targeting DNA topoisomerase I in tumor cells, inducing apoptosis.Fórmula:C15H24N2OPureza:97.33% - 99.28%Cor e Forma:SolidPeso molecular:248.36DBEQ
CAS:<p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>Fórmula:C22H20N4Pureza:98.93% - ≥95%Cor e Forma:SolidPeso molecular:340.42Ziyuglycoside I
CAS:<p>Ziyuglycoside I (Gouguside 7) has anti-inflammatory activity, could be used as an active ingredient for cosmetics.</p>Fórmula:C41H66O13Pureza:98.987% - ≥95%Cor e Forma:SolidPeso molecular:766.95AZD5582 acetate (1258392-53-8 free base)
<p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>Fórmula:C60H82N8O10Pureza:97.76%Cor e Forma:SolidPeso molecular:1075.363-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96PHA-793887
CAS:<p>PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.</p>Fórmula:C19H31N5O2Pureza:98.02% - >99.99%Cor e Forma:SolidPeso molecular:361.48Avadomide
CAS:<p>Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.</p>Fórmula:C14H14N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:286.29Dipyrithione
CAS:<p>Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity</p>Fórmula:C10H8N2O2S2Pureza:99.9%Cor e Forma:Beige Crystalline PowderPeso molecular:252.31Phenoxodiol
CAS:<p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>Fórmula:C15H12O3Pureza:98.07%Cor e Forma:SolidPeso molecular:240.25SBI-0640756
CAS:<p>SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.</p>Fórmula:C23H14ClFN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:404.82Anisomycin
CAS:<p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>Fórmula:C14H19NO4Pureza:98.33% - 99.81%Cor e Forma:White Crystalline SolidPeso molecular:265.3Tofacitinib
CAS:<p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>Fórmula:C16H20N6OPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:312.37Onvansertib
CAS:<p>Onvansertib (NMS-1286937) is a PLK1 inhibitor with high selectivity and oral activity. Onvansertib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C24H27F3N8O3Pureza:98.3% - 99.88%Cor e Forma:SolidPeso molecular:532.52Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Fórmula:C21H24O6Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:372.41Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Cor e Forma:White To Off-White PowderPeso molecular:362.46ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Fórmula:C22H29ClN4O3Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:432.94Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Fórmula:C14H21N3OPureza:99.53% - 99.87%Cor e Forma:SolidPeso molecular:247.34R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78Prexasertib Mesylate Hydrate
CAS:<p>Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.</p>Fórmula:C19H25N7O6SCor e Forma:SolidPeso molecular:479.51CA-5f
CAS:<p>CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.</p>Fórmula:C24H24N2O3Pureza:99.69%Cor e Forma:SolidPeso molecular:388.46Atopaxar hydrochloride
CAS:<p>Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.</p>Fórmula:C29H39ClFN3O5Cor e Forma:SolidPeso molecular:564.1M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Fórmula:C13H16O4Pureza:97.8%Cor e Forma:SolidPeso molecular:236.26Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Cor e Forma:SolidPeso molecular:467.39Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:625.56R547
CAS:<p>R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.</p>Fórmula:C18H21F2N5O4SPureza:90% - 99.64%Cor e Forma:SolidPeso molecular:441.45
