Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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Rapanone
CAS:<p>Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.</p>Fórmula:C19H30O4Pureza:99.56%Cor e Forma:SolidPeso molecular:322.44HS-173
CAS:<p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>Fórmula:C21H18N4O4SPureza:99.33% - 99.64%Cor e Forma:SolidPeso molecular:422.46RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Fórmula:C22H17F2N2·CH3O4SPureza:99.72%Cor e Forma:SolidPeso molecular:458.48Fidaxomicin
CAS:<p>Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.</p>Fórmula:C52H74Cl2O18Pureza:99.76% - 99.82%Cor e Forma:SolidPeso molecular:1058.04Leachianone A
CAS:<p>Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.</p>Fórmula:C26H30O6Pureza:98.53% - 99.79%Cor e Forma:SolidPeso molecular:438.51S55746 hydrochloride
CAS:<p>S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.</p>Fórmula:C43H43ClN4O6Pureza:98%Cor e Forma:SolidPeso molecular:747.28L-Glutamic acid monosodium salt
CAS:<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Fórmula:C5H8NO4·NaPureza:99.93%Cor e Forma:White Solid CrystallinePeso molecular:169.11Kevetrin hydrochloride
CAS:<p>Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential</p>Fórmula:C5H10ClN3SPureza:99.32% - 99.93%Cor e Forma:SolidPeso molecular:179.67Parthenolide
CAS:<p>Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.</p>Fórmula:C15H20O3Pureza:98.19% - 99.46%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:248.323-O-Acetyloleanolic acid
CAS:<p>3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells.</p>Fórmula:C32H50O4Pureza:98% - 99.57%Cor e Forma:SolidPeso molecular:498.74PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Fórmula:C19H15F3O5Pureza:99.78%Cor e Forma:SolidPeso molecular:380.31Alofanib
CAS:<p>Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.</p>Fórmula:C19H15N3O6SPureza:99.53% - 99.81%Cor e Forma:SolidPeso molecular:413.4Citric acid
CAS:<p>Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits, a food additive and a natural preservative. High-Quality, Low-Cost!</p>Fórmula:C6H8O7Pureza:98.88%Cor e Forma:White Solid CrystallinePeso molecular:192.12Curcumol
CAS:<p>Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.</p>Fórmula:C15H24O2Pureza:98.99% - 99.87%Cor e Forma:SolidPeso molecular:236.35ONO-4059 analog
CAS:<p>ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.</p>Fórmula:C25H24N6O3Pureza:99.25%Cor e Forma:SolidPeso molecular:456.5Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Cor e Forma:Off-White To Light Yellow PowdPeso molecular:958.22Galgravin
CAS:<p>Galgravin combats inflammation, safeguards neurons, promotes neurite growth, and resists Abeta25-35 and MPP+ toxicity.</p>Fórmula:C22H28O5Pureza:99.75% - 99.88%Cor e Forma:SolidPeso molecular:372.45Ursonic Acid
CAS:<p>Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton.</p>Fórmula:C30H46O3Pureza:98.90% - >99.99%Cor e Forma:SolidPeso molecular:454.68Dinoprost tromethamine salt
CAS:<p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>Fórmula:C24H45NO8Pureza:99.73%Cor e Forma:Natural Form Crystals SolidPeso molecular:475.62SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Fórmula:C21H13ClF3N3O2Pureza:98.44%Cor e Forma:SolidPeso molecular:431.8Sanguinarine
CAS:<p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>Fórmula:C20H14NO4Pureza:99.04% - 99.76%Cor e Forma:SolidPeso molecular:332.33Puromycin aminonucleoside
CAS:<p>Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.</p>Fórmula:C12H18N6O3Pureza:99.85% - 99.9%Cor e Forma:SolidPeso molecular:294.31Clovamide
CAS:<p>Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T.</p>Fórmula:C18H17NO7Pureza:97.12% - 97.68%Cor e Forma:SolidPeso molecular:359.33Polydatin
CAS:<p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>Fórmula:C20H22O8Pureza:97.2% - 98.94%Cor e Forma:White Fine PowderPeso molecular:390.38Salermide
CAS:<p>Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.</p>Fórmula:C26H22N2O2Pureza:97.09% - 99.55%Cor e Forma:SolidPeso molecular:394.47RX-3117
CAS:<p>RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.</p>Fórmula:C10H12FN3O4Pureza:97.46%Cor e Forma:SolidPeso molecular:257.22Piperlongumine
CAS:<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Fórmula:C17H19NO5Pureza:97.03% - 99.90%Cor e Forma:SolidPeso molecular:317.34Quercetin Dihydrate
CAS:<p>Quercetin Dihydrate (Sophoretin) is a flavonoid natural product that activates or inhibits the activity of many proteins. It activates SIRT1 and inhibits PI3K.</p>Fórmula:C15H10O7·2H2OPureza:97.77%Cor e Forma:Yellow SolidPeso molecular:338.27LY2409881 trihydrochloride
CAS:<p>LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.</p>Fórmula:C24H32Cl4N6OSPureza:≥95%Cor e Forma:SolidPeso molecular:594.43ODQ
CAS:<p>ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.</p>Fórmula:C9H5N3O2Pureza:98.98%Cor e Forma:Off-White To Light Yellow PowderPeso molecular:187.15Cycleanine
CAS:<p>Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.</p>Fórmula:C38H42N2O6Pureza:98.04% - 99.57%Cor e Forma:SolidPeso molecular:622.75AMAROGENTIN
CAS:<p>Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.</p>Fórmula:C29H30O13Pureza:99.98% - ≥95%Cor e Forma:SolidPeso molecular:586.54PS47
CAS:<p>PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.</p>Fórmula:C17H15ClO2Pureza:99.09%Cor e Forma:SolidPeso molecular:286.75Epothilone B
CAS:<p>Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum.</p>Fórmula:C27H41NO6SPureza:99.79% - 99.84%Cor e Forma:White PowderPeso molecular:507.68Atractylenolide II
CAS:<p>Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.</p>Fórmula:C15H20O2Pureza:99.89% - 99.93%Cor e Forma:SolidPeso molecular:232.32Pitavastatin calcium
CAS:<p>Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.</p>Fórmula:C50H46CaF2N2O8Pureza:98.89% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:880.98D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Fórmula:C23H18N4O3Pureza:99.7% - 99.96%Cor e Forma:SolidPeso molecular:398.41Capsazepine
CAS:<p>Capsazepine, a TRPV1 antagonist (IC50: 562 nM), blocks capsaicin-induced heat pain.</p>Fórmula:C19H21ClN2O2SPureza:98% - 99.78%Cor e Forma:White To Off-White PowderPeso molecular:376.9API-1
CAS:<p>API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .</p>Fórmula:C13H15N5O6Pureza:97.15%Cor e Forma:SolidPeso molecular:337.29RIPGBM
CAS:<p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>Fórmula:C26H21FN2O3Pureza:99.45%Cor e Forma:SolidPeso molecular:428.45L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13Pectolinarin
CAS:<p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>Fórmula:C29H34O15Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:622.57SC144
CAS:<p>SC144 is an orally active small-molecule gp130 inhibitor.</p>Fórmula:C16H11FN6OPureza:99.20%Cor e Forma:SolidPeso molecular:322.3PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Cor e Forma:SolidPeso molecular:501.5SIRT7 inhibitor 97491
CAS:<p>SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.</p>Fórmula:C15H12ClN3OPureza:99.79%Cor e Forma:SolidPeso molecular:285.73Dapivirine
CAS:<p>Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H19N5Pureza:98% - 99.77%Cor e Forma:SolidPeso molecular:329.4MIRA-1
CAS:<p>MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activity</p>Fórmula:C8H9NO4Pureza:99.94%Cor e Forma:SolidPeso molecular:183.16Lonicerin
CAS:<p>Lonicerin: antioxidant, anti-arthritic, antifungal; potential for combined fungal arthritis treatment from C. albicans.</p>Fórmula:C27H30O15Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:594.52DIM-C-pPhOH
CAS:<p>CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.</p>Fórmula:C23H18N2OPureza:98.61%Cor e Forma:SolidPeso molecular:338.4Bafetinib
CAS:<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Fórmula:C30H31F3N8OPureza:94.16% - 99.68%Cor e Forma:SolidPeso molecular:576.62
