Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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Iberdomide
CAS:<p>Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).</p>Fórmula:C25H27N3O5Pureza:97.01%Cor e Forma:SolidPeso molecular:449.5Tivantinib
CAS:<p>Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.</p>Fórmula:C23H19N3O2Pureza:98% - 99.41%Cor e Forma:SolidPeso molecular:369.42Fulvestrant
CAS:<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>Fórmula:C32H47F5O3SPureza:99.1% - >99.99%Cor e Forma:White PowderPeso molecular:606.77YK-4-279
CAS:<p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>Fórmula:C17H13Cl2NO4Pureza:99.80% - ≥95%Cor e Forma:SolidPeso molecular:366.2NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Fórmula:C38H47ClN4O4Pureza:98.77%Cor e Forma:SolidPeso molecular:659.26Cobimetinib
CAS:<p>Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H21F3IN3O2Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:531.31YH239-EE
CAS:<p>YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.</p>Fórmula:C25H27Cl2N3O4Pureza:99.61%Cor e Forma:SolidPeso molecular:504.41SCR7 pyrazine
CAS:<p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>Fórmula:C18H12N4OSPureza:98.72% - 99.85%Cor e Forma:SolidPeso molecular:332.38Penicillic acid
CAS:<p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>Fórmula:C8H10O4Pureza:98%Cor e Forma:Needles From Petroleum Ether Slight Yellow PowderPeso molecular:170.16MK-4101
CAS:<p>MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.</p>Fórmula:C24H24F5N5OPureza:98.2% - 99.13%Cor e Forma:SolidPeso molecular:493.47Vistusertib
CAS:<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Fórmula:C25H30N6O3Pureza:97.08% - 99.06%Cor e Forma:SolidPeso molecular:462.54Domatinostat
CAS:<p>Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).</p>Fórmula:C23H21N5O3SPureza:99.57% - 99.74%Cor e Forma:SolidPeso molecular:447.51Suberoyl bis-hydroxamic acid
CAS:<p>SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.</p>Fórmula:C8H16N2O4Pureza:99.88%Cor e Forma:SolidPeso molecular:204.22JX06
CAS:<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Fórmula:C10H16N2O2S4Pureza:99.4%Cor e Forma:SolidPeso molecular:324.51MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Fórmula:C25H23Cl2N5OPureza:99.228% - 99.94%Cor e Forma:SolidPeso molecular:480.39Geranyl acetate
CAS:<p>Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.</p>Fórmula:C12H20O2Pureza:98% - 99.36%Cor e Forma:Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Peso molecular:196.29Isosilybin A
CAS:<p>Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (</p>Fórmula:C25H22O10Pureza:98.79%Cor e Forma:SolidPeso molecular:482.44CIL56
CAS:<p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>Fórmula:C23H27N3O5S2Pureza:99.46% - 99.91%Cor e Forma:SolidPeso molecular:489.61TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Fórmula:C26H28N6Pureza:98% - 99.72%Cor e Forma:White Crystalline PowderPeso molecular:424.542,5-dimethyl Celecoxib
CAS:<p>2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.</p>Fórmula:C18H16F3N3O2SPureza:99.85%Cor e Forma:SolidPeso molecular:395.4dl-Maackiain
CAS:<p>1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.</p>Fórmula:C16H12O5Pureza:97.36% - 99.89%Cor e Forma:SolidPeso molecular:284.26Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Fórmula:C20H18O10Pureza:98.8% - 99.33%Cor e Forma:SolidPeso molecular:418.35Oxibendazole
CAS:<p>Oxibendazole: a benzimidazole antiparasitic for horses and pets against various worms.</p>Fórmula:C12H15N3O3Pureza:99.3% - 99.88%Cor e Forma:Crystalline SolidPeso molecular:249.27CCI-007
CAS:<p>CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485</p>Fórmula:C15H16N2O5SPureza:97.61%Cor e Forma:SolidPeso molecular:336.36SZL P1-41
CAS:<p>SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.</p>Fórmula:C24H24N2O3SPureza:99.60% - 99.87%Cor e Forma:SolidPeso molecular:420.52HS-1793
CAS:<p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>Fórmula:C16H12O3Pureza:98.16% - 99.82%Cor e Forma:SolidPeso molecular:252.265-Geranoxy-7-methoxycoumarin
CAS:<p>5-Geranoxy-7-methoxycoumarin shows antifungal activity.</p>Fórmula:C20H24O4Pureza:98.94% - 99.99%Cor e Forma:SolidPeso molecular:328.4FX1
CAS:<p>FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).</p>Fórmula:C14H9ClN2O4S2Pureza:97.59%Cor e Forma:SolidPeso molecular:368.82GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.131A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Fórmula:C16H16F3N3Pureza:99.71%Cor e Forma:SolidPeso molecular:307.31Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Fórmula:C14H14N2O4SPureza:97.67% - >99.99%Cor e Forma:Yellow CrystallinePeso molecular:306.34TJ191
CAS:<p>TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.</p>Fórmula:C13H21NO2SPureza:99.28%Cor e Forma:SolidPeso molecular:255.38BTZO-1
CAS:<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Fórmula:C13H8N2OSPureza:99.46%Cor e Forma:SolidPeso molecular:240.28Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Fórmula:C50H83NO21Pureza:98.42% - 99.94%Cor e Forma:White To Light YellowPeso molecular:1034.19MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Fórmula:C20H37N3O4Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:383.53Serdemetan
CAS:<p>Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.</p>Fórmula:C21H20N4Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:328.41BC-1258
CAS:<p>BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.</p>Fórmula:C22H22N4S2Pureza:97.48% - 99.64%Cor e Forma:SolidPeso molecular:406.57Dubermatinib
CAS:<p>Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.</p>Fórmula:C24H30ClN7O2SPureza:98.65% - 99.58%Cor e Forma:SolidPeso molecular:516.06R406
CAS:<p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Cor e Forma:SolidPeso molecular:628.63PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Fórmula:C24H25ClN6OPureza:99.13%Cor e Forma:SolidPeso molecular:448.95Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Cor e Forma:SolidPeso molecular:439.38Ginkgolide B
CAS:<p>Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.</p>Fórmula:C20H24O10Pureza:98.66% - 99.81%Cor e Forma:White Crystal PowderPeso molecular:424.4Tripterin
CAS:<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Fórmula:C29H38O4Pureza:98.56% - 99.8%Cor e Forma:Red Crystalline PowderPeso molecular:450.61AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:381.43Solasodine
CAS:<p>Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.</p>Fórmula:C27H43NO2Pureza:99.64% - 99.94%Cor e Forma:SolidPeso molecular:413.64Tamibarotene
CAS:<p>Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic</p>Fórmula:C22H25NO3Pureza:98.55% - 99.73%Cor e Forma:Crystalline SolidPeso molecular:351.44MI-136
CAS:<p>MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.</p>Fórmula:C23H21F3N6SPureza:98.63% - 99.12%Cor e Forma:SolidPeso molecular:470.51S55746 hydrochloride
CAS:<p>S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.</p>Fórmula:C43H43ClN4O6Pureza:98%Cor e Forma:SolidPeso molecular:747.28
