Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(137 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(94 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6231 produtos de "Apoptose"
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Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Fórmula:C56H87NO16Pureza:97.76% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:1030.29Calcimycin
CAS:Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.Fórmula:C29H37N3O6Pureza:98%Cor e Forma:SolidPeso molecular:523.62Amantadine
CAS:Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.Fórmula:C10H17NPureza:99.73% - 99.94%Cor e Forma:Hexakistetrahedral Crystals By Sublimation SolidPeso molecular:151.25Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Fórmula:C21H22O5Pureza:99.03% - 99.9%Cor e Forma:SolidPeso molecular:354.4Inecalcitol
CAS:Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity.Cost-effective and quality-assured.Fórmula:C26H40O3Pureza:99.96%Cor e Forma:SolidPeso molecular:400.59GSK1324726A
CAS:GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
Fórmula:C25H23ClN2O3Pureza:98.34% - 99.85%Cor e Forma:SolidPeso molecular:434.91MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Cor e Forma:SolidPeso molecular:314.38MPI-0479605
CAS:MPI-0479605 is an ATP competitive and selective inhibitor.Fórmula:C22H29N7OPureza:97.59% - >99.99%Cor e Forma:SolidPeso molecular:407.51(-)-Alkannin
CAS:(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.Fórmula:C16H16O5Pureza:98.18% - 98.8%Cor e Forma:White Or Slightly Yellow Crystalline Powder SolidPeso molecular:288.3(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Fórmula:C19H18ClN5OSPureza:99.01% - 99.92%Cor e Forma:SolidPeso molecular:399.9Ref: TM-T6026
2mg34,00€5mg55,00€1mL*10mM (DMSO)58,00€10mg89,00€25mg170,00€50mg269,00€100mg424,00€200mg593,00€C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Fórmula:C24H19N3O6Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:445.42Ref: TM-T2452
2mg46,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg92,00€25mg185,00€50mg360,00€100mg532,00€500mg1.144,00€Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Fórmula:C18H18N2O4Pureza:96.74% - 99.45%Cor e Forma:SolidPeso molecular:326.35Ref: TM-T6980
5mg67,00€1mL*10mM (DMSO)74,00€10mg92,00€25mg193,00€50mg358,00€100mg537,00€500mg1.134,00€Aniline mustard
CAS:Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.Fórmula:C10H13Cl2NPureza:99.54%Cor e Forma:SolidPeso molecular:218.12Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Fórmula:C19H19FO4Pureza:97.58% - 98%Cor e Forma:SolidPeso molecular:330.35Glycitein
CAS:1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.Fórmula:C16H12O5Pureza:99.23% - 99.94%Cor e Forma:White PowderPeso molecular:284.26Ref: TM-T6S0325
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg65,00€25mg92,00€50mg137,00€100mg193,00€200mg286,00€Sodium taurodeoxycholate hydrate
CAS:Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations ofFórmula:C26H44NO6S·Na·H2OPureza:99.78%Cor e Forma:SolidPeso molecular:539.70Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably
Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Cor e Forma:SolidPeso molecular:530.5NSC 73150
CAS:6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.Fórmula:C12H12N4O2Pureza:99.84%Cor e Forma:SolidPeso molecular:244.25Ref: TM-T9398
1mg93,00€1mL*10mM (DMSO)166,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C23H20N6OPureza:99.71%Cor e Forma:SolidPeso molecular:396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFórmula:C30H33ClN4O2Pureza:98% - 99.09%Cor e Forma:SolidPeso molecular:517.06Ref: TM-T2103
2mg46,00€5mg74,00€1mL*10mM (DMSO)85,00€10mg112,00€25mg200,00€50mg320,00€100mg528,00€200mg755,00€BMS-833923
CAS:BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).Fórmula:C30H27N5OPureza:99.47% - 99.76%Cor e Forma:SolidPeso molecular:473.57Ref: TM-T2299
5mg52,00€1mL*10mM (DMSO)56,00€10mg77,00€25mg120,00€50mg187,00€100mg339,00€200mg497,00€500mg790,00€EI1
CAS:EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.Fórmula:C23H26N4O2Pureza:99.93%Cor e Forma:SolidPeso molecular:390.484-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Fórmula:C16H19N5SPureza:97.18%Cor e Forma:SolidPeso molecular:313.42Ref: TM-T8794
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€pimpinellin
CAS:Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
Fórmula:C13H10O5Pureza:99.85% - ≥95%Cor e Forma:SolidPeso molecular:246.22β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Fórmula:C15H14O3Pureza:99.76% - 99.88%Cor e Forma:SolidPeso molecular:242.27MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Cor e Forma:SolidPeso molecular:474.57Ref: TM-T3653
2mg39,00€5mg58,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg167,00€50mg260,00€100mg409,00€200mg590,00€DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Cor e Forma:White SolidPeso molecular:432.46Ref: TM-T6202
2mg38,00€5mg55,00€1mL*10mM (DMSO)56,00€10mg94,00€25mg157,00€50mg264,00€100mg358,00€200mg490,00€Isatin
CAS:Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.Fórmula:C8H5NO2Pureza:98.92%Cor e Forma:Yellow To Reddish Crystalline SolidPeso molecular:147.13BDA-366
CAS:BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies itsFórmula:C24H29N3O4Pureza:98.61%Cor e Forma:SoildPeso molecular:423.53BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Fórmula:C18H17NO5Pureza:97.76%Cor e Forma:SolidPeso molecular:327.33Ref: TM-T14033
1mg34,00€2mg44,00€5mg64,00€1mL*10mM (DMSO)71,00€10mg92,00€25mg195,00€50mg313,00€100mg467,00€UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Fórmula:C32H43N5O2Pureza:98% - 99.04%Cor e Forma:SolidPeso molecular:529.72H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Fórmula:C23H38N10O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:614.61Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Cor e Forma:White PowderPeso molecular:150.92AES-350
CAS:AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.Fórmula:C18H20N2O3Pureza:98.82%Cor e Forma:SolidPeso molecular:312.36N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Fórmula:C21H31N3O5SPureza:98.69% - 98.69%Cor e Forma:SolidPeso molecular:437.55Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Fórmula:C30H48O5Pureza:96.91% - 99.97%Cor e Forma:SolidPeso molecular:488.70Ref: TM-T5S0506
2mg34,00€5mg49,00€1mL*10mM (DMSO)49,00€10mg75,00€25mg137,00€50mg215,00€100mg319,00€200mg474,00€Medicarpin
CAS:Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.Fórmula:C16H14O4Pureza:99.32% - 99.86%Cor e Forma:SolidPeso molecular:270.28Ref: TM-TN1918
1mg109,00€1mL*10mM (DMSO)235,00€5mg260,00€10mg385,00€25mg628,00€50mg872,00€100mg1.153,00€200mg1.584,00€Isobavachalcone
CAS:Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury inFórmula:C20H20O4Pureza:98% - 99.76%Cor e Forma:SolidPeso molecular:324.37Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Fórmula:C22H24N2O7SPureza:98.13% - 99.95%Cor e Forma:SolidPeso molecular:460.50FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Fórmula:C28H32O6Pureza:97% - 97.90%Cor e Forma:SolidPeso molecular:464.55Ref: TM-T6838
2mg43,00€5mg63,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Cor e Forma:SolidPeso molecular:387.86Polyporenic acid C
CAS:Polyporenic acid C shows inhibitory activity against human collagenase.Fórmula:C31H46O4Pureza:96.84% - 99.90%Cor e Forma:SolidPeso molecular:482.69Ref: TM-TN1153
1mg66,00€5mg177,00€1mL*10mM (DMSO)212,00€10mg304,00€25mg509,00€50mg710,00€100mg982,00€RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Fórmula:C14H12O3S2Pureza:98.49% - 99.55%Cor e Forma:SolidPeso molecular:292.37Ref: TM-T1798
1mg35,00€5mg66,00€1mL*10mM (DMSO)89,00€10mg96,00€25mg187,00€50mg279,00€100mg420,00€200mg607,00€Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Cor e Forma:Yellow SolidPeso molecular:384.24Ref: TM-T2399
5mg50,00€1mL*10mM (DMSO)50,00€10mg60,00€25mg75,00€50mg92,00€100mg137,00€200mg213,00€500mg353,00€IACS-010759
CAS:IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.Fórmula:C25H25F3N6O4SPureza:99.54% - 99.73%Cor e Forma:SolidPeso molecular:562.56Ref: TM-T5337
1mg49,00€2mg70,00€5mg107,00€1mL*10mM (DMSO)141,00€10mg165,00€25mg334,00€50mg485,00€100mg710,00€200mg964,00€Ketorolac
CAS:Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.Fórmula:C15H13NO3Pureza:99.68%Cor e Forma:White Crystalline Or White PowderPeso molecular:255.27TPCA-1
CAS:TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinasesFórmula:C12H10FN3O2SPureza:95.03% - 97.86%Cor e Forma:SolidPeso molecular:279.29Oxysophoridine
CAS:Oxysophoridine protects against brain ischemia and heart damage through antioxidant, anti-apoptotic, and anti-inflammatory effects.Fórmula:C15H24N2O2Pureza:98.15% - >99.99%Cor e Forma:SolidPeso molecular:264.36ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Cor e Forma:SolidPeso molecular:477.4Ref: TM-T8970
1mg43,00€5mg85,00€1mL*10mM (DMSO)92,00€10mg110,00€25mg215,00€50mg334,00€100mg467,00€200mg672,00€Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Fórmula:C23H21Cl2FN4O3Pureza:98.69% - 99.78%Cor e Forma:SolidPeso molecular:491.34
