Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(142 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(138 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(14 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(56 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5903 produtos de "Apoptose"
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Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Fórmula:C22H14Pureza:99.97%Cor e Forma:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Peso molecular:278.35Flurochloridone
CAS:Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.Fórmula:C12H10Cl2F3NOPureza:99.86%Cor e Forma:SolidPeso molecular:312.12Riviciclib hydrochloride
CAS:Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.Fórmula:C21H20ClNO5·HClPureza:99.51%Cor e Forma:SolidPeso molecular:438.3SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Cor e Forma:Orange PowderPeso molecular:568.09Camptothecin
CAS:Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.Fórmula:C20H16N2O4Pureza:99.52% - 99.88%Cor e Forma:Solid PowderPeso molecular:348.35NPB
CAS:NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)Fórmula:C29H31Cl2N3O2Pureza:99.93%Cor e Forma:SolidPeso molecular:524.48SAR405838
CAS:MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.Fórmula:C29H34Cl2FN3O3Pureza:98.63%Cor e Forma:SolidPeso molecular:562.5L-Cystathionine
CAS:<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Fórmula:C7H14N2O4SPureza:96.43% - >99.99%Cor e Forma:SolidPeso molecular:222.26Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Fórmula:C23H18F4N6O2Pureza:99.05% - 99.51%Cor e Forma:SolidPeso molecular:486.42Mcl1-IN-11
CAS:Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.Fórmula:C38H41N3O5S2Pureza:98%Cor e Forma:SolidPeso molecular:683.88KS106
CAS:KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3STAT3-IN-11
CAS:STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35Propiomazine
CAS:Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.Fórmula:C20H24N2OSPureza:98.5%Cor e Forma:SolidPeso molecular:340.48EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Fórmula:C36H38F2O2Pureza:98.11% - 98.11%Cor e Forma:SolidPeso molecular:540.68AZD-5991 Racemate
CAS:<p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>Fórmula:C35H34ClN5O3S2Cor e Forma:SolidPeso molecular:672.26DNL343
CAS:DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.Fórmula:C20H19ClF3N3O4Pureza:99.96%Cor e Forma:SolidPeso molecular:457.83Allethrin
CAS:Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.Fórmula:C19H26O3Pureza:99.52%Peso molecular:302.41VU 0364739 hydrochloride
CAS:VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.Fórmula:C26H28ClFN4O2Pureza:99.36%Cor e Forma:SolidPeso molecular:482.98Declopramide
CAS:Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.Fórmula:C13H20ClN3OPureza:98.53%Cor e Forma:SolidPeso molecular:269.77MI-389
CAS:MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.Fórmula:C35H35FN6O6Pureza:98.12%Cor e Forma:SolidPeso molecular:654.69Bax activator-1
CAS:Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].Fórmula:C29H36N4O3Cor e Forma:SolidPeso molecular:488.62Anticancer agent 47
CAS:Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.Fórmula:C19H14N2O4SCor e Forma:SolidPeso molecular:366.39BRD0476
CAS:BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76Verticillin A
CAS:Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.Fórmula:C30H28N6O6S4Pureza:98%Cor e Forma:SolidPeso molecular:696.84SK-7041
CAS:SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.Fórmula:C19H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:339.39Fomesafen
CAS:Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).Fórmula:C15H10ClF3N2O6SPureza:99.91% - 99.93%Cor e Forma:White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicidePeso molecular:438.76PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Cor e Forma:SolidPeso molecular:374.97GSK962
CAS:<p>GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.</p>Fórmula:C14H18N2OPureza:99.75%Cor e Forma:SolidPeso molecular:230.31GW-3333
CAS:GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.Fórmula:C22H36N4O4Pureza:98%Cor e Forma:SolidPeso molecular:420.55Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Fórmula:C29H38FN3O5Pureza:97.07% - 98.07%Cor e Forma:SolidPeso molecular:527.63Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Fórmula:C29H30N6O2Cor e Forma:SolidPeso molecular:494.59p-DDAP
CAS:p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.Fórmula:C18H31NOPureza:98%Cor e Forma:SolidPeso molecular:277.44PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43Tryptophanamide
CAS:Tryptophanamide is a chymotrypsin inhibitor.Fórmula:C11H13N3OPureza:98%Cor e Forma:SolidPeso molecular:203.24HDAC6-IN-4
CAS:HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.Fórmula:C30H38N2O5Cor e Forma:SolidPeso molecular:506.63Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Fórmula:C26H21ClF3N5O3S2Cor e Forma:SolidPeso molecular:608.05NHI-2
CAS:NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.Fórmula:C17H12F3NO3Pureza:99.981%Cor e Forma:SolidPeso molecular:335.28MG-262
CAS:<p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>Fórmula:C25H42BN3O6Cor e Forma:SolidPeso molecular:491.43M199
CAS:M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.Fórmula:C17H17N3OPureza:98%Cor e Forma:SolidPeso molecular:279.34AZD 1152 (hydrochloride)
CAS:AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.Fórmula:C26H33Cl2FN7O6PCor e Forma:SolidPeso molecular:660.47BMS-242
CAS:BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.Fórmula:C28H35NO4Pureza:98%Cor e Forma:SolidPeso molecular:449.58VU0424465
CAS:VU0424465 is a mGlu5-selective allosteric agonist.Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36Mitochonic Acid 35
CAS:Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.Fórmula:C19H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:341.36SCAL-266
CAS:SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.Fórmula:C27H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:511.54DC-5163
CAS:DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.Fórmula:C18H20ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:361.89CAY10747
CAS:CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.Fórmula:C42H48FNO6Cor e Forma:SolidPeso molecular:681.83CDK9-IN-18
CAS:CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5Dipin
CAS:Dipin is an Antineoplastic.Fórmula:C12H24N6O2P2Pureza:98%Cor e Forma:SolidPeso molecular:346.31Gemcitabine monophosphate
CAS:R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Fórmula:C9H12F2N3O7PCor e Forma:SolidPeso molecular:343.18
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