Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5618 produtos de "Apoptose"
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Sabizabulin
CAS:<p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>Fórmula:C21H19N3O4Pureza:98.10% - 99.79%Cor e Forma:SolidPeso molecular:377.39CBS9106
CAS:<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Fórmula:C18H21ClF3N3O3Pureza:98.98%Cor e Forma:SolidPeso molecular:419.83HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Cor e Forma:SolidPeso molecular:388.41HTH-01-091
CAS:<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Fórmula:C26H28Cl2N4O2Pureza:98.4%Cor e Forma:SolidPeso molecular:499.43UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Fórmula:C22H21N3OPureza:98.76%Cor e Forma:SolidPeso molecular:343.42RET-IN-23
CAS:<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Fórmula:C28H28FN11Pureza:97.46%Cor e Forma:SolidPeso molecular:537.59UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Fórmula:C27H45N7O3Pureza:99.80%Cor e Forma:SolidPeso molecular:515.69TNIK-IN-3
CAS:<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Fórmula:C23H18FN3O2Pureza:98.39%Cor e Forma:SolidPeso molecular:387.41Gallium maltolate
CAS:Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.Fórmula:C18H15GaO9Pureza:99.61% - 99.67%Cor e Forma:SolidPeso molecular:445.03K-8012
CAS:<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Fórmula:C23H23FN4Pureza:99.72%Cor e Forma:SolidPeso molecular:374.45GCN2-IN-1
CAS:<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Fórmula:C19H18N10OPureza:99.49% - 99.64%Cor e Forma:SolidPeso molecular:402.41TT01001
CAS:<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Fórmula:C15H19Cl2N3O2SPureza:99.93%Cor e Forma:SolidPeso molecular:376.3Triparanol
CAS:<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Fórmula:C27H32ClNO2Pureza:99.72%Cor e Forma:SolidPeso molecular:438Dasatinib hydrochloride
CAS:<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Fórmula:C22H27Cl2N7O2SPureza:99.88% - 99.98%Cor e Forma:SolidPeso molecular:524.47NecroX-7
CAS:<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Fórmula:C24H29N3O3SPureza:98.22%Cor e Forma:SolidPeso molecular:439.57CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Fórmula:C20H20N2O4Pureza:98.78% - 99.79%Cor e Forma:SolidPeso molecular:352.38UK-101
CAS:<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Fórmula:C25H48N2O5SiPureza:99.08% - 99.25%Cor e Forma:SolidPeso molecular:484.74EGFR-IN-11
CAS:<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Fórmula:C29H35N9O2SPureza:99.93%Cor e Forma:SolidPeso molecular:573.71OR-1896
CAS:OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Fórmula:C13H15N3O2Pureza:99.33%Cor e Forma:SolidPeso molecular:245.28CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Fórmula:C25H22ClFN2OPureza:99.82%Cor e Forma:SolidPeso molecular:420.91Etomoxir
CAS:<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Fórmula:C17H23ClO4Pureza:98% - 99.39%Cor e Forma:SolidPeso molecular:326.82GSK2593074A
CAS:<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Fórmula:C27H23N5OSPureza:99.76%Cor e Forma:SolidPeso molecular:465.57MBM-55
CAS:<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Fórmula:C28H27FN6O2Pureza:99.83%Cor e Forma:SolidPeso molecular:498.55TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Fórmula:C24H21N3O3SPureza:99.58%Cor e Forma:SolidPeso molecular:431.51Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Fórmula:C14H13ClN4Pureza:99.29% - 99.85%Cor e Forma:SolidPeso molecular:272.73GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Fórmula:C18H19ClN6O4S2Pureza:98.79%Cor e Forma:SolidPeso molecular:482.96Benitrobenrazide
CAS:Benitrobenrazide (Hexokinase 2 inhibitor 1) is a novel orally available hexokinase 2 (HK2) inhibitor with anticancer and antitumor activity for cancer research.Fórmula:C14H11N3O6Pureza:96.87%Cor e Forma:SolidPeso molecular:317.25BCL6-IN-7
CAS:<p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>Fórmula:C18H15ClN6OPureza:99.03%Cor e Forma:SolidPeso molecular:366.8Ro 90-7501
CAS:<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Fórmula:C20H16N6Pureza:97.21% - 99.72%Cor e Forma:SolidPeso molecular:340.38C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Fórmula:C24H47NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:397.63Tubulin inhibitor 32
CAS:<p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>Fórmula:C18H19N3O3Pureza:99.92%Cor e Forma:SolidPeso molecular:325.36Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Fórmula:C19H21N5O3Pureza:99.72%Cor e Forma:SolidPeso molecular:367.4XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Fórmula:C18H12N2O2Pureza:97.01%Cor e Forma:SolidPeso molecular:288.3CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Fórmula:C31H30Br2N4O2Pureza:98.63%Cor e Forma:SolidPeso molecular:650.4NSC49652
CAS:<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Fórmula:C14H11NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:225.24CMLD-2
CAS:CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Fórmula:C31H31NO6Pureza:99.99%Cor e Forma:SolidPeso molecular:513.58D609
CAS:D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.Fórmula:C11H15KOS2Pureza:97.67% - 99.56%Cor e Forma:Off-White PowderPeso molecular:266.46SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Fórmula:C17H20N4O2Pureza:99.86%Cor e Forma:SolidPeso molecular:312.37AZA1
CAS:<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Fórmula:C22H20N6Pureza:99.75%Cor e Forma:SolidPeso molecular:368.43LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Fórmula:C8H5Cl3FNOPureza:98.99%Cor e Forma:SolidPeso molecular:256.49RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Fórmula:C15H9ClN2O2S3Pureza:98.12%Cor e Forma:SolidPeso molecular:380.89Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Fórmula:C29H27F3N6OPureza:99.64%Cor e Forma:SolidPeso molecular:532.56Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Fórmula:C10H22N4O2S2Pureza:98.83%Cor e Forma:SolidPeso molecular:294.44FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Fórmula:C22H27F3N4O2SPureza:99.44%Cor e Forma:SolidPeso molecular:468.54Imipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Fórmula:C19H24N2Pureza:99.4%Cor e Forma:White To Off-White /Hydrochloride/ SolidPeso molecular:280.41RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Fórmula:C29H25FN4O4Pureza:98.27%Cor e Forma:SolidPeso molecular:512.53BC 11 hydrobromide
CAS:<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Fórmula:C8H12BBrN2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:290.97TL4-12
CAS:TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.Fórmula:C25H27F3N6O2Pureza:98.38%Cor e Forma:SolidPeso molecular:500.52Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Fórmula:C42H50FN7O8S2Pureza:99.05%Cor e Forma:SolidPeso molecular:864.02Ro 41-5253
CAS:<p>Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.</p>Fórmula:C28H36O5SPureza:98%Cor e Forma:SolidPeso molecular:484.65
