Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
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AP-III-a4
CAS:AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.Fórmula:C31H43FN8O3Pureza:98.24% - 99.90%Cor e Forma:SolidPeso molecular:594.72Ref: TM-T6759
1mg49,00€2mg73,00€5mg114,00€1mL*10mM (DMSO)148,00€10mg178,00€25mg349,00€50mg557,00€100mg888,00€200mg1.305,00€ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Fórmula:C12H22ClN3OSPureza:99.3%Cor e Forma:SolidPeso molecular:291.84Ref: TM-T8931L
5mg34,00€1mL*10mM (DMSO)34,00€10mg50,00€25mg90,00€50mg138,00€100mg198,00€200mg296,00€500mg469,00€ON1231320
CAS:ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.Fórmula:C22H15F2N5O3SPureza:97.31%Cor e Forma:SolidPeso molecular:467.45Ref: TM-T19664
1mg46,00€5mg88,00€1mL*10mM (DMSO)95,00€10mg132,00€25mg259,00€50mg404,00€100mg592,00€200mg843,00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Fórmula:C23H27N7O3S2Pureza:98.69% - 99.97%Cor e Forma:SolidPeso molecular:513.64Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Fórmula:C17H11NO4Pureza:98.98% - 99.96%Cor e Forma:SolidPeso molecular:293.27Ref: TM-T3S1227
1mg57,00€5mg133,00€1mL*10mM (DMSO)172,00€10mg205,00€25mg350,00€50mg515,00€100mg735,00€Nimustine Hydrochloride
CAS:Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.Fórmula:C9H14Cl2N6O2Pureza:98.80%Cor e Forma:SolidPeso molecular:309.15Ref: TM-T5017
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg71,00€25mg92,00€50mg152,00€100mg268,00€200mg398,00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Fórmula:C28H25ClFN3O5Pureza:99.97%Cor e Forma:SolidPeso molecular:537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Fórmula:C23H25N2·C2HO4C2H2O4Cor e Forma:Dark Green Crystals With A Metallic LusterPeso molecular:463.51HYPOCRELLIN B
CAS:HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.Fórmula:C30H24O9Pureza:98% - 98.87%Cor e Forma:SolidPeso molecular:528.51Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Fórmula:C22H19F2N3O4SPureza:98.74% - 99.32%Cor e Forma:SolidPeso molecular:459.47Ref: TM-T3712
1mg55,00€2mg78,00€5mg92,00€1mL*10mM (DMSO)94,00€10mg150,00€25mg244,00€50mg437,00€100mg625,00€PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Fórmula:C18H11F3N2OPureza:95.49% - 99.16%Cor e Forma:SolidPeso molecular:328.29Ref: TM-T3105
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg170,00€50mg259,00€100mg409,00€Larotrectinib sulfate
CAS:Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).Fórmula:C21H22F2N6O2·H2O4SPureza:98.62% - 99.76%Cor e Forma:SolidPeso molecular:526.51Ref: TM-T6880
2mg37,00€5mg54,00€1mL*10mM (DMSO)63,00€10mg88,00€25mg124,00€50mg155,00€100mg259,00€500mg623,00€VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Fórmula:C19H17ClN2O5Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:388.8Ref: TM-T2258
1mg39,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg150,00€25mg250,00€50mg384,00€100mg557,00€200mg787,00€MSC 2032964A
CAS:MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.
Fórmula:C16H13F3N6OPureza:99.76%Cor e Forma:SolidPeso molecular:362.31Ref: TM-T33514
1mg84,00€2mg97,00€5mg158,00€10mg240,00€25mg393,00€50mg560,00€100mg753,00€200mg1.035,00€CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Fórmula:C19H22ClN5OPureza:98% - 99.9%Cor e Forma:SolidPeso molecular:371.86LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Fórmula:C26H29NO5Pureza:98.1% - 98.22%Cor e Forma:SolidPeso molecular:435.51Ref: TM-T3494
2mg44,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Fórmula:C21H26N6O2Pureza:96.01% - ≥98%Cor e Forma:SolidPeso molecular:394.47α-Hederin
CAS:Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.Fórmula:C41H66O12Pureza:99.44% - 99.89%Cor e Forma:SolidPeso molecular:750.96Ref: TM-T3368
1mg37,00€5mg69,00€10mg88,00€1mL*10mM (DMSO)88,00€25mg144,00€50mg205,00€100mg303,00€200mg445,00€BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFórmula:C25H26ClN5O3Pureza:99.02%Cor e Forma:SolidPeso molecular:479.96RO8994
CAS:RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).Fórmula:C31H31Cl2FN4O4Pureza:99.31% - 99.44%Cor e Forma:SolidPeso molecular:613.51Ref: TM-T3517
1mg38,00€2mg50,00€5mg82,00€1mL*10mM (DMSO)100,00€10mg120,00€25mg219,00€50mg344,00€100mg512,00€
