Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
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RA375
CAS:RA375 inhibits RPN13, enhances UPR, ROS, apoptosis, and is 10x more potent against cancer than RA190 due to nitro rings and chloroacetamide.Fórmula:C30H25ClN4O7Pureza:99.56%Cor e Forma:SolidPeso molecular:588.99Atractylenolide II
CAS:Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.Fórmula:C15H20O2Pureza:99.89% - 99.93%Cor e Forma:SolidPeso molecular:232.32Ref: TM-T5S0168
1mg37,00€5mg71,00€1mL*10mM (DMSO)84,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Fórmula:C50H46CaF2N2O8Pureza:98.89% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:880.98SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Fórmula:C25H27N7O3S2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€1mL*10mM (DMSO)148,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€4-Hydroxybenzyl alcohol
CAS:4-Hydroxybenzyl alcohol aids brain injury recovery, boosts Nrf2/Prdx6/PDI, and hinders angiogenesis, showing promise in cancer therapy.Fórmula:C7H8O2Pureza:97.65% - 98.25%Cor e Forma:SolidPeso molecular:124.14API-1
CAS:API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .Fórmula:C13H15N5O6Pureza:97.15%Cor e Forma:SolidPeso molecular:337.29Ref: TM-T8969
1mg56,00€5mg118,00€1mL*10mM (DMSO)126,00€10mg197,00€25mg356,00€50mg532,00€100mg745,00€200mg982,00€RIPGBM
CAS:RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).Fórmula:C26H21FN2O3Pureza:99.45%Cor e Forma:SolidPeso molecular:428.45Ref: TM-T16754
2mg35,00€5mg54,00€1mL*10mM (DMSO)60,00€10mg93,00€25mg177,00€50mg318,00€100mg530,00€200mg677,00€Thalidomide-5-OH
CAS:Thalidomide-5-OH (2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBNFórmula:C13H10N2O5Pureza:98.94%Cor e Forma:SolidPeso molecular:274.23Buprofezin
CAS:Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.Fórmula:C16H23N3OSPureza:99.02% - 99.73%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:305.44Desloratadine
CAS:Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties.Fórmula:C19H19ClN2Pureza:99.79% - >99.99%Cor e Forma:SolidPeso molecular:310.82L-Glutamic acid
CAS:L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13Fenoldopam mesylate
CAS:Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties.Fórmula:C16H16ClNO3·CH4O3SPureza:99.19% - 99.94%Cor e Forma:SolidPeso molecular:401.86SC144
CAS:SC144 is an orally active small-molecule gp130 inhibitor.Fórmula:C16H11FN6OPureza:99.20%Cor e Forma:SolidPeso molecular:322.3SIRT7 inhibitor 97491
CAS:SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.Fórmula:C15H12ClN3OPureza:99.79%Cor e Forma:SolidPeso molecular:285.73Ref: TM-T39233
1mg96,00€5mg235,00€1mL*10mM (DMSO)259,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Fórmula:C30H31F3N8OPureza:94.16% - 99.68%Cor e Forma:SolidPeso molecular:576.62Ref: TM-T6311
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)95,00€10mg98,00€25mg150,00€50mg178,00€100mg333,00€200mg432,00€PHT-427
CAS:PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).Fórmula:C20H31N3O2S2Pureza:97.54% - >99.99%Cor e Forma:SolidPeso molecular:409.61ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Cor e Forma:SolidPeso molecular:371.414'-bromo-Resveratrol
CAS:4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)Fórmula:C14H11BrO2Pureza:99.00%Cor e Forma:SolidPeso molecular:291.14Chrysosplenol D
CAS:Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.Fórmula:C18H16O8Pureza:97.87% - 99.98%Cor e Forma:SolidPeso molecular:360.31NAE-IN-M22
CAS:NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.Fórmula:C20H24Cl2N2Pureza:97.65%Cor e Forma:SolidPeso molecular:363.32Ref: TM-T8816
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg305,00€25mg518,00€50mg742,00€100mg1.018,00€500mg2.062,00€
