Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(128 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6172 produtos de "Apoptose"
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Toripalimab
CAS:Toripalimab is a humanized anti-PD-1 monoclonal antibody used as an immune checkpoint inhibitor in research for advanced malignancies like nasopharyngeal carcinoma.Pureza:95% - 95.2% (SDS-PAGE); 96.8% (SEC-HPLC)Cor e Forma:LiquidIvuxolimab
CAS:Ivuxolimab is a human IgG2 antibody that acts as an OX40 agonist, promoting T cell responses for anti-tumor immunity research.Pureza:95% - 96.0% (SDS-PAGE); 96.7% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.18 kDaMicrotubule inhibitor 8
CAS:Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].Fórmula:C21H15N3O2SCor e Forma:SolidPeso molecular:373.43Pifithrin-β
CAS:potent p53 inhibitorFórmula:C16H16N2SPureza:98%Cor e Forma:SolidPeso molecular:268.38Exlinkibart
CAS:Exlinkibart (LVGN-6051) is a humanised monoclonal antibody and agonist targeting CD137/TNFRSF9, inducing cytotoxic T lymphocyte (CTL) proliferation.Pureza:95% - 97.7% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.44 kDaAfelimomab
CAS:Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].Cor e Forma:LiquidIratumumab
CAS:Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Cor e Forma:LiquidMDM2-p53-IN-18
CAS:MDM2-p53-IN-18, also known as Compd A-7b, is an inhibitor of the MDM2-p53 interaction [1].Fórmula:C19H16Cl2FN3O4Cor e Forma:SolidPeso molecular:440.25Pucotenlimab
CAS:Pucotenlimab (HX008) is an anti-PD-1 mAb that blocks PD-1/PD-L1/2 interactions, restoring immune function against solid tumours.Pureza:95%Cor e Forma:LiquidPeso molecular:144.77 kDaPQA-18
CAS:PQA-18, an inhibitor of p21-activated kinase 2 (PAK2; IC50 = 10 nM), is derived from Ppc-1 (product number 42352) and exhibits immunosuppressive properties. It inhibits IL-2 production in Jurkat T cells induced by Concanavalin A (product number 14951) with an IC50 of 400 nM. Topically applied at 0.1%, PQA-18 reduces the severity of atopic dermatitis, serum IgE levels, and skin thickness in the NC/Nga mouse model. A lower concentration of 0.05% also decreases skin nerve fiber density in NC/Nga mice. Additionally, PQA-18 administered at 4 mg/kg improves graft survival in a rat small intestine transplantation model.Fórmula:C25H31NO4Cor e Forma:SolidPeso molecular:409.52Gilvetmab
CAS:Gilvetmab is a caninized anti-PD-1 antibody approved for veterinary use, researched for stage I-III mast cell tumors and stage II-III melanoma in dogs.Pureza:95% - 97.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:147.95 kDaTavolixizumab
CAS:Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancerCor e Forma:LiquidInezetamab
CAS:Inezetamab is a bispecific monoclonal antibody functioning as an MSLN inhibitor and CD40 agonist, suitable for investigating solid tumours.Pureza:95% - 99.1% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:195.98 kDaLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Cor e Forma:LiquidRemtolumab
CAS:Remtolumab (ABT-122) is a dual inhibitor of TNFα and IL-17A for rheumatoid arthritis research.Cor e Forma:LiquidBoserolimab
CAS:Boserolimab, Humanized anti-CD27 agonistic mAb, blocks CD70 binding to CD27, used for lung cancer research.Pureza:95% - 95%Cor e Forma:LiquidAnti-Mouse VEGFR-2 Antibody (DC101)
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.Pureza:99%Cor e Forma:LiquidPeso molecular:150 kDaAnti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12)
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is an IgG2a, κ antibody inhibitor derived from mice, targeting phosphorylated PD-1/CD279 in both mice and humans.Cor e Forma:Odour LiquidAnti-Mouse PD-1 Antibody (S-5001)
Anti-MousePD-1Antibody (S-5001) is an IgG1 antibody inhibitor that targets mouse PD-1.Cor e Forma:Odour LiquidCosibelimab
CAS:Cosibelimab, a fully human monoclonal antibody, blocks PD-L1, enabling ADCC and CDC against cancer cells.Cor e Forma:Liquid
